Robert J. Riley - Publications, H-index & Citations

Robert J. Riley

AstraZeneca

40H指数

108论文数

5.5K被引数

收录论文 15

发表时间

Studying the right transporter at the right time: an in vitro strategy for assessing drug-drug interaction risk during drug discovery and development

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2022-11-01

OAAI

Elsby, Robert; Atkinson, Hayley; Butler, Philip; Riley, Robert J.

The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development

ARCHIVES OF TOXICOLOGY

IF6.9

2020-05-06

OAAI

Walker, Paul A.; Ryder, Stephanie; Lavado, Andrea; Dilworth, Clive; Riley, Robert J.

Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2019-09-20

PREAI

Lucas, Adam J.; Sproston, Joanne L.; Barton, Patrick; Riley, Robert J.

The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice

ARCHIVES OF TOXICOLOGY

IF6.9

2018-05-02

PREAI

Wilson, C. E.; Dickie, A. P.; Schreiter, K.; Wehr, R.; Wilson, E. M.; Bial, J.; Scheer, N.; Wilson, I. D.; Riley, R. J.

Hepatic transporter drug-drug interactions: an evaluation of approaches and methodologies

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2017-11-23

PREAI

Williamson, Beth; Riley, Robert J.

The pharmacokinetics and metabolism of lumiracoxib in chimeric humanized and murinized FRG mice

BIOCHEMICAL PHARMACOLOGY

IF5.6

2017-07-01

OAAI

Dickie, A. P.; Wilson, C. E.; Schreiter, K.; Wehr, R.; Wilson, E. M.; Bial, J.; Scheer, N.; Wilson, I. D.; Riley, R. J.

Hepatic drug transporters: the journey so far

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2016-01-08

PREAI

Riley, R. J.; Foley, S. A.; Barton, P.; Soars, M. G.; Williamson, B.

Cytochrome P450 time-dependent inhibition and induction: advances in assays, risk analysis and modelling

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2015-02-08

PREAI

Riley, Robert J.; Wilson, Claire E.

Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells

ACTA PHARMACOLOGICA SINICA

IF8.4

2010-01-05

OAAI

Martin, Philip; Riley, Robert; Thompson, Paul; Williams, Dominic; Back, David; Owen, Andrew

Mechanism-based inhibition of cytochrome P450 enzymes: An evaluation of early decision making in vitro approaches and drug-drug interaction prediction methods

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2009-02-01

PREAI

Grime, Kenneth H.; Bird, James; Ferguson, Douglas; Riley, Robert J.

Discovery of potent and selective adamantane-based small-molecule P2X7 receptor antagonists/interleukin-1β,6 inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-10-27

PREAI

Furber, Mark; Alcaraz, Lilian; Bent, Janice E.; Beyerbach, Armin; Bowers, Keith; Braddock, Martin; Caffrey, Moya V.; Cladingboel, David; Collington, John; Donald, David K.; Fagura, Malbinder; Ince, Frank; Kinchin, Elizabeth C.; Laurent, Celine; Lawson, Mandy; Luker, Timothy J.; Mortimore, Michael M. P.; Pimm, Austen D.; Riley, Robert J.; Roberts, Nicola; Robertson, Mark; Theaker, Jill; Thorne, Philip V.; Weaver, Richard; Webborn, Peter; Willis, Paul

Time-dependent CYP inhibition

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY

IF3.4

2007-02-01

110

PREAI

Riley, Robert J.; Grime, Ken; Weaver, Richard

Predictice ADMET studies, the challenges and the opportunities

CURRENT OPINION IN CHEMICAL BIOLOGY

IF6.1

2004-08-01

PREAI