未登录 Application of an Interdisciplinary Approach to Form Selection in Drug Development Reid, Darren L.; Faul, Margaret M.; Lopez-Mejias, Vilmali; Agarwal, Prashant; Bergauer, Markus; Blue, Laura E.; Chaves, Mary K.; Chung, John; Cooke, Melanie; Farrell, Robert P.; Huckle, James E.; Kelly, Ron C.; Kiang, Y. -h.; Li, Weikun; Ortiz, Adrian; Wu, Qiong 分享 收藏
Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRASG12C Inhibitor Zhang, Liang; Griffin, Daniel J.; Beaver, Matthew G.; Blue, Laura E.; Borths, Christopher J.; Brown, Derek B.; Caille, Seb; Chen, Ying; Cherney, Alan H.; Cochran, Brian M.; Colyer, John T.; Corbett, Michael T.; Correll, Tiffany L.; Crockett, Richard D.; Dai, Xi-Jie; Dornan, Peter K.; Farrell, Robert P.; Hedley, Simon J.; Hsieh, Hsiao-Wu; Huang, Liang; Huggins, Seth; Liu, Min; Lovette, Michael A.; Quasdorf, Kyle; Powazinik, William; Reifman, Jonathan; Robinson, Jo Anna; Sangodkar, Rahul P.; Sharma, Sonika; Kumar, Srividya Sharvan; Smith, Austin G.; St-Pierre, Gabrielle; Tedrow, Jason S.; Thiel, Oliver R.; Truong, Jonathan V.; Walker, Shawn D.; Wei, Carolyn S.; Wilsily, Ashraf; Xie, Yong; Yang, Ning; Parsons, Andrew T. 分享 收藏
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Discovery of 6-(2,4-Difluorophenoxy)-2[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase Goldstein, David M.; Soth, Michael; Gabriel, Tobias; Dewdney, Nolan; Kuglstatter, Andreas; Arzeno, Humberto; Chen, Jeffrey; Bingenheimer, William; Dalrymple, Stacie A.; Dunn, James; Farrell, Robert; Frauchiger, Sandra; La Fargue, JoAnn; Ghate, Manjiri; Graves, Bradford; Hill, Ronald J.; Li, Fujun; Litman, Renee; Loe, Brad; McIntosh, Joel; McWeeney, Daniel; Papp, Eva; Park, Jaehyeon; Reese, Harlan F.; Roberts, Richard T.; Rotstein, David; Pablo, Bong San; Sarma, Keshab; Stahl, Martin; Sung, Man-Ling; Suttman, Rebecca T.; Sjogren, Eric B.; Tan, Yunchou; Trejo, Alejandra; Welch, Mary; Weller, Paul; Wong, Brian R.; Zecic, Hasim 分享 收藏
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