Javier del Pino - Publications, H-index & Citations

Javier del Pino

complutense university of madrid

21H指数

135论文数

1.4K被引数

收录论文 47

发表时间

Cholinergic Transmission Dysregulation and Neurodegeneration Induced by Thyroid Signaling Disruption Following Butylparaben Single and Repeated Treatment 丁基对羟基苯甲酸酯单次和重复处理后甲状腺信号紊乱引起的胆碱能传递失调和神经退行性变

Biology

IF3.5

2026-03-03

OAAI

Paula Moyano; Andrea Flores; Javier Sanjuan; Jose Carlos Plaza; Lucía Guerra-Menéndez; Luisa Abascal; Olga Mateo; Javier del Pino

Neurodegeneration, Oxidative Stress, NGF/TrkA/P75NTR, and PGE2 Dysregulation Induced by PFOS Single and Repeated Treatment: Partial Protection by T3 and Other Therapeutic Approaches PFOS单次和重复处理诱导的神经退行性变、氧化应激、NGF/TrkA/P75NTR及PGE2失调：T3和其他治疗方法的局部保护作用

Pharmaceutics

IF5.5

2026-02-27

OAAI

Paula Moyano; Andrea Flores; Javier Sanjuan; José Carlos Plaza; Lucía Guerra-Menéndez; María Victoria Naval; Luisa Abascal; Olga Mateo-Sierra; Javier del Pino

Imidacloprid unique and repeated treatment produces cholinergic transmission disruption and apoptotic cell death in SN56 cells 吡虫啉独特和重复治疗在SN56细胞中产生胆碱能传递破坏和凋亡细胞死亡

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2024-11-01

OAAI

Moyano, Paula; Flores, Andrea; San Juan, Javier; Garcia, Jimena; Anadon, Maria Jose; Plaza, Jose Carlos; Naval, Maria Victoria; Fernandez, Maria de la Cabeza; Guerra-Menendez, Lucia; del Pino, Javier

Thyroid Hormone Neuroprotection Against Perfluorooctane Sulfonic Acid Cholinergic and Glutamatergic Disruption and Neurodegeneration Induction

BIOMEDICINES

IF3.9

2024-10-24

OAAI

Moyano, Paula; Guzman, Gabriela; Flores, Andrea; Garcia, Jimena; Guerra-Menendez, Lucia; Sanjuan, Javier; Plaza, Jose Carlos; Abascal, Luisa; Mateo, Olga; Del Pino, Javier

Neurodegenerative Proteinopathies Induced by Environmental Pollutants: Heat Shock Proteins and Proteasome as Promising Therapeutic Tools

PHARMACEUTICS

IF5.5

2023-07-30

OAAI

Moyano, Paula; Sola, Emma; Naval, Maria Victoria; Guerra-Menendez, Lucia; Fernandez, Maria De la Cabeza; del Pino, Javier

Bisphenol-A Neurotoxic Effects on Basal Forebrain Cholinergic Neurons In Vitro and In Vivo 双酚a对基底前脑胆碱能神经元的神经毒性作用

BIOLOGY-BASEL

IF3.5

2023-05-28

OAAI

Flores, Andrea; Moyano, Paula; Sola, Emma; Garcia, Jose Manuel; Garcia, Jimena; Frejo, Maria Teresa; Guerra-Menendez, Lucia; Labajo, Elena; Lobo, Ines; Abascal, Luisa; del Pino, Javier

Insulin Signaling Disruption and INF-? Upregulation Induce A?1-42 and Hyperphosphorylated-Tau Proteins Synthesis and Cell Death after Paraquat Treatment of Primary Hippocampal Cells

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2022-11-17

OAAI

Abascal, Maria Luisa; Sanjuan, Javier; Moyano, Paula; Sola, Emma; Flores, Andrea; Garcia, Jose Manuel; Garcia, Jimena; Frejo, Maria Teresa; del Pino, Javier

Neuroprotective mechanisms of multitarget 7-aminophenanthridin-6 (5H)-one derivatives against metal-induced amyloid proteins generation and aggregation

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2022-09-01

OAAI

Moyano, Paula; Vicente-Zurdo, David; Blazquez-Barbadillo, Cristina; Menendez, J. Carlos; Gonzalez, Juan F.; Rosales-Conrado, Noelia; del Pino, Javier

Cadmium-induced neurotoxic effects on rat basal forebrain cholinergic system through thyroid hormones disruption

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

IF4.2

2022-02-01

OAAI

Sola, Emma; Moyano, Paula; Flores, Andrea; Garcia, Jimena; Manuel Garcia, Jose; Anadon, Maria Jose; Teresa Frejo, Maria; Pelayo, Adela; de la Cabeza Fernandez, Maria; del Pino, Javier

Neuroprotective Action of Multitarget 7-Aminophenanthridin-6(5H)-one Derivatives against Metal-Induced Cell Death and Oxidative Stress in SN56 Cells

ACS CHEMICAL NEUROSCIENCE

IF3.9

2021-08-30

OAAI

Moyano, Paula; Vicente-Zurdo, David; Blazquez-Barbadillo, Cristina; Carlos Menendez, J.; Gonzalez, Juan F.; Rosales-Conrado, Noelia; del Pino, Javier

Aryl Hydrocarbon Receptor Activation Produces Heat Shock Protein 90 and 70 Overexpression, Prostaglandin E2/Wnt/β-Catenin Signaling Disruption, and Cell Proliferation in MCF-7 and MDA-MB-231 Cells after 24 h and 14 Days of Chlorpyrifos Treatment

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2021-08-23

OAAI

Moyano, Paula; Manuel Garcia, Jose; Garcia, Jimena; Pelayo, Adela; Munoz-Calero, Pilar; Teresa Frejo, Maria; Flores, Andrea; del Pino, Javier

Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt/β-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment 毒死蜱通过单次和重复治疗后胆碱能和Wnt/β-catenin信号通路破坏，ache-r上调和氧化应激产生，诱导MCF-7和MDA-MB-231细胞增殖

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2021-06-01

PREAI

Moyano, Paula; Manuel Garcia, Jose; Garcia, Jimena; Pelayo, Adela; Munoz-Calero, Pilar; Teresa Frejo, Maria; Jose Anadon, Maria; Victoria Naval, Maria; Flores, Andrea; Alejandra Mirat, Vega; Del Pino, Javier

Discovery of 7-aminophenanthridin-6-one as a new scaffold for matrix metalloproteinase inhibitors with multitarget neuroprotective activity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-01-01

PREAI

Rocchi, Damiano; Blazquez-Barbadillo, Cristina; Agamennone, Mariangela; Laghezza, Antonio; Tortorella, Paolo; Vicente-Zurdo, David; Rosales-Conrado, Noelia; Moyano, Paula; del Pino, Javier; Gonzalez, Juan F.; Menendez, J. Carlos

Paraquat Treatment Compromises the Clearance of β-Amyloid and Tau Proteins and Induces Primary Hippocampal Neuronal Cell Death through HSP70, P20S, and TFEB Disruption

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2020-11-06

PREAI

Moyano, Paula; Sanjuna, Javier; Manuel Garcia, Jose; Garcia, Jimena; Teresa Frejo, Maria; Victoria Naval, Maria; del Pino, Javier

Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

IF6.1

2020-10-01

PREAI

Moyano, Paula; Manuel Garcia, Jose; Garcia, Jimena; Jose Anadon, Maria; Victoria Naval, Maria; Teresa Frejo, Maria; Sola, Emma; Pelayo, Adela; Del Pino, Javier

Dysregulation of prostaglandine E2 and BDNF signaling mediated by estrogenic dysfunction induces primary hippocampal neuronal cell death after single and repeated paraquat treatment

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2020-10-01

PREAI

Moyano, Paula; Sanjuan, Javier; Manuel Garcia, Jose; Jose Anadon, Maria; Victoria Naval, Maria; Sola, Emma; Garcia, Jimena; Teresa Frejo, Maria; del Pino, Javier

Primary hippocampal estrogenic dysfunction induces synaptic proteins alteration and neuronal cell death after single and repeated paraquat exposure

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2020-02-01

PREAI

Moyano, Paula; Sanjuan, Javier; Garcia, Jose Manuel; Anadon, Maria Jose; Lobo, Margarita; Pelayo, Adela; Garcia, Jimena; Frejoa, Maria Teresa; del Pino, Javier

Proteasome 20S and Rab5 Alteration after 24 h and 14 Days Chlorpyrifos Exposure Lead to β-Amyloid and Tau Protein Level Increases and SN56 Neuronal Cell Death

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2019-10-03

PREAI

Moyano, Paula; Manuel Garcia, Jose; Teresa Frejo, Maria; Lobo, Margarita; Garcia, Jimena; del Pino, Javier

Oxidative stress and cell death induction by amitraz and its metabolite BTS-27271 mediated through cytochrome P450 and NRF2 pathway alteration in primary hippocampal cell

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2019-07-01

PREAI

Moyano, Paula; Ruiz, Matilde; Manuel Garcia, Jose; Teresa Frejo, Maria; Anadon Baselga, Maria Jose; Lobo, Margarita; Garcia, Jimena; Del Pino, Javier

Manganese induced ROS and AChE variants alteration leads to SN56 basal forebrain cholinergic neuronal loss after acute and long-term treatment

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2019-03-01

PREAI

Moyano, Paula; Manuel Garcia, Jose; Jose Anadon, Maria; Lobo, Margarita; Garcia, Jimena; Teresa Frejo, Maria; Sola, Emma; Pelayo, Adela; del Pino, Javier

研究方向