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IL-1β stimulates a novel axis within the NFκB pathway in endothelial cells regulated by IKKα and TAK-1 Craig, Rachel; Mcintosh, Kathryn; Ho, Ka Ho; Mcculloch, Ashley; Riley, Christopher; Lawson, Christopher; Mackay, Simon P.; Paul, Andrew; Coats, Paul; Plevin, Robin 分享 收藏
Design and Synthesis of Novel Aminoindazole-pyrrolo[2,3-b]pyridine Inhibitors of IKKα That Selectively Perturb Cellular Non-Canonical NF-κB Signalling Riley, Christopher; Ammar, Usama; Alsfouk, Aisha; Anthony, Nahoum G.; Baiget, Jessica; Berretta, Giacomo; Breen, David; Huggan, Judith; Lawson, Christopher; McIntosh, Kathryn; Plevin, Robin; Suckling, Colin J.; Young, Louise C.; Paul, Andrew; Mackay, Simon P. 分享 收藏
DRD2 activation inhibits choroidal neovascularization in patients with Parkinson's disease and age-related macular degeneration Mathis, Thibaud; Baudin, Florian; Mariet, Anne-Sophie; Augustin, Sebastien; Bricout, Marion; Przegralek, Lauriane; Roubeix, Christophe; Benzenine, Eric; Blot, Guillaume; Nous, Caroline; Kodjikian, Laurent; Mauget-Faysse, Martine; Sahel, Jose-Alain; Plevin, Robin; Zeitz, Christina; Delarasse, Cecile; Guillonneau, Xavier; Creuzot-Garcher, Catherine; Quantin, Catherine; Hunot, Stephane; Sennlaub, Florian 分享 收藏
IL-1β stimulates a novel, IKKα-dependent, NIK-independent activation of non-canonical NFκB signalling McIntosh, Kathryn; Khalaf, Yousif H.; Craig, Rachel; West, Christopher; McCulloch, Ashley; Waghmare, Ajay; Lawson, Christopher; Chan, Edmond Y. W.; Mackay, Simon; Paul, Andrew; Plevin, Robin 分享 收藏
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Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells 蛋白酶激活受体2 (PAR2) 拮抗作用可减少支气管上皮细胞中促炎性细胞因子的产生 Bailo, Mariarca; Dunning, L.; Brzeszczynska, J.; Mcintosh, K.; Plevin, R.; Martin, S. L.; Sergeant, G. P.; Goodyear, C. S.; Litherland, G. S.; Lockhart, J. C.; Crilly, A. 分享 收藏
REDUCTION OF INFLAMMATORY CYTOKINE PRODUCTION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) EPITHELIAL CELLS BY PROTEASE ACTIVATED RECEPTOR 2 (PAR2) ANTAGONISM Bailo, M.; Dunning, L.; Brzeszczynska, J.; McIntosh, K.; Plevin, R.; Martin, S. L.; Sergeant, G. P.; Goodyear, C. S.; Litherland, G. J.; Lockhart, J. C.; Crilly, A. 分享 收藏
Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis Chen, Ming; Zhang, Jiangwen; Berger, Alice H.; Diolombi, Moussa S.; Ng, Christopher; Fung, Jacqueline; Bronson, Roderick T.; Castillo-Martin, Mireia; Thin, Tin Htwe; Cordon-Cardo, Carlos; Plevin, Robin; Pandolfi, Pier Paolo 分享 收藏
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The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover Wilkinson, David J.; Desilets, Antoine; Lin, Hua; Charlton, Sarah; Arques, Maria del Carmen; Falconer, Adrian; Bullock, Craig; Hsu, Yu-Chen; Birchall, Kristian; Hawkins, Alastair; Thompson, Paul; Ferrell, William R.; Lockhart, John; Plevin, Robin; Zhang, Yadan; Blain, Emma; Lin, Shu-Wha; Leduc, Richard; Milner, Jennifer M.; Rowan, Andrew D. 分享 收藏
Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers Anthony, Nahoum G.; Baiget, Jessica; Berretta, Giacomo; Boyd, Marie; Breen, David; Edwards, Joanne; Gamble, Carly; Gray, Alexander I.; Harvey, Alan L.; Hatziieremia, Sophia; Ho, Ka Ho; Huggan, Judith K.; Lang, Stuart; Llona-Minguez, Sabin; Luo, Jia Lin; McIntosh, Kathryn; Paul, Andrew; Plevin, Robin J.; Robertson, Murray N.; Scott, Rebecca; Suckling, Colin J.; Sutcliffe, Oliver B.; Young, Louise C.; Mackay, Simon P. 分享 收藏
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Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology Huesa, Carmen; Ortiz, Ana C.; Dunning, Lynette; McGavin, Laura; Bennett, Louise; McIntosh, Kathryn; Crilly, Anne; Kurowska-Stolarska, Mariola; Plevin, Robin; van't Hof, Rob J.; Rowan, Andrew D.; McInnes, Iain B.; Goodyear, Carl S.; Lockhart, John C.; Ferrell, William R. 分享 收藏
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