Stefan L. Marklund - Publications, H-index & Citations

Stefan L. Marklund

Department of Medical Biosciences

87H指数

393论文数

3.5W被引数

收录论文 89

发表时间

Seeds from ALS patients homozygous for the SOD1 D90A mutation transmit two types of SOD1 aggregation and motor neuron disease ALS患者中SOD1 D90A纯合突变携带者的种子细胞传递两种类型的SOD1聚集和运动神经元疾病

Acta Neuropathologica

IF9.3

2026-09-01

OAAI

Caitlin Henne; Isabelle Sigfridsson; Thomas Brännström; Karin M. E. Forsberg; Stefan L. Marklund; Per Zetterström; Peter M. Andersen

N-Truncated Superoxide Dismutase-1 in Cerebrospinal Fluid Is Folded and Active 脑脊液中截断型超氧化物歧化酶-1是折叠且具有活性的

Journal of Neurochemistry

IF4

2026-02-10

OAAI

Laura Leykam; Karin M. E. Forsberg; Peter M. Andersen; Thomas Brännström; Sophia Weiner; John Rönnholm; Kaj Blennow; Henrik Zetterberg; Stefan L. Marklund; Johan Gobom; Per Zetterström

Diverse effects of coexpression of human SOD1 variants on motor neuron disease 人类SOD1变体共表达对运动神经元疾病的多样化影响

HUMAN MOLECULAR GENETICS

IF3.2

2025-06-01

OAAI

Tokuda, Eiichi; Leykam, Laura; Zetterstrom, Per; Brannstrom, Thomas; Andersen, Peter M.; Marklund, Stefan L.

Specific analysis of SOD1 enzymatic activity in CSF from ALS patients with and without SOD1 mutations

NEUROBIOLOGY OF DISEASE

IF5.6

2024-11-01

OAAI

Leykam, Laura; Forsberg, Karin M. E.; Nordstrom, Ulrika; Hjertkvist, Karin; Oberg, Agneta; Jonsson, Eva; Andersen, Peter M.; Marklund, Stefan L.; Zetterstrom, Per

Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis

CELL REPORTS

IF6.9

2023-10-01

OAAI

Tsioras, Konstantinos; Smith, Kevin C.; Edassery, Seby L.; Garjani, Mehraveh; Li, Yichen; Williams, Chloe; Mckenna, Elizabeth D.; Guo, Wenxuan; Wilen, Anika P.; Hark, Timothy J.; Marklund, Stefan L.; Ostrow, Lyle W.; Gilthorpe, Jonathan D.; Ichida, Justin K.; Kalb, Robert G.; Savas, Jeffrey N.; Kiskinis, Evangelos

The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1

BRAIN COMMUNICATIONS

IF4.5

2023-01-27

OAAI

Park, Julien H.; Nordstroem, Ulrika; Tsiakas, Konstantinos; Keskin, Isil; Elpers, Christiane; Mannil, Manoj; Heller, Raoul; Nolan, Melinda; Alburaiky, Salam; Zetterstroem, Per; Hempel, Maja; Schara-Schmidt, Ulrike; Biskup, Saskia; Steinacker, Petra; Otto, Markus; Weishaupt, Jochen; Hahn, Andreas; Santer, Rene; Marquardt, Thorsten; Marklund, Stefan L.; Andersen, Peter M.

Widespread CNS pathology in amyotrophic lateral sclerosis homozygous for the D90A SOD1 mutation

ACTA NEUROPATHOLOGICA

IF9.3

2022-11-16

OAAI

Forsberg, Karin M.; Graffmo, Karin S.; Stenvall, Erica; Tabikh, Naima; Marklund, Stefan L.; Brannstrom, Thomas; Andersen, Peter M.

Alteration of Mitochondrial Integrity as Upstream Event in the Pathophysiology of SOD1-ALS 线粒体完整性的改变是SOD1-ALS病理生理中的上游事件

CELLS

IF5.2

2022-04-06

OAAI

Guenther, Rene; Pal, Arun; Williams, Chloe; Zimyanin, Vitaly L.; Liehr, Maria; von Neubeck, Clare; Krause, Mechthild; Parab, Mrudula G.; Petri, Susanne; Kalmbach, Norman; Marklund, Stefan L.; Sterneckert, Jared; Andersen, Peter Munch; Wegner, Florian; Gilthorpe, Jonathan D.; Hermann, Andreas

Infantile SOD1 deficiency syndrome caused by a homozygous SOD1 variant with absence of enzyme activity

BRAIN

IF11.7

2021-11-11

OAAI

Ezer, Shlomit; Daana, Muhannad; Park, Julien H.; Yanovsky-Dagan, Shira; Nordstrom, Ulrika; Basal, Adily; Edvardson, Simon; Saada, Ann; Otto, Markus; Meiner, Vardiella; Marklund, Stefan L.; Andersen, Peter Munch; Harel, Tamar

Peripheral administration of SOD1 aggregates does not transmit pathogenic aggregation to the CNS of SOD1 transgenic mice

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2021-06-22

OAAI

Keskin, Isil; Ekhtiari Bidhendi, Elaheh; Marklund, Matthew; Andersen, Peter M.; Brannstrom, Thomas; Marklund, Stefan L.; Nordstrom, Ulrika

Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2020-09-14

OAAI

Lehmann, Manuela; Marklund, Matthew; Bolender, Anna-Lena; Bidhendi, Elaheh E.; Zetterstrom, Per; Andersen, Peter M.; Brannstrom, Thomas; Marklund, Stefan L.; Gilthorpe, Jonathan D.; Nordstrom, Ulrika

The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension

ACTA NEUROPATHOLOGICA

IF9.3

2019-03-12

OAAI

Keskin, Isil; Forsgren, Elin; Lehmann, Manuela; Andersen, Peter M.; Brannstrom, Thomas; Lange, Dale J.; Synofzik, Matthis; Nordstrom, Ulrika; Zetterstrom, Per; Marklund, Stefan L.; Gilthorpe, Jonathan D.

A novel p.Ser108LeufsTer15 SOD1 mutation leading to the formation of a premature stop codon in an apparently sporadic ALS patient: insights into the underlying pathomechanisms

NEUROBIOLOGY OF AGING

IF3.5

2018-12-01

OAAI

Canosa, Antonio; De Marco, Giovanni; Lomartire, Annarosa; Rinaudo, Maria Teresa; Di Cunto, Ferdinando; Turco, Emilia; Barberis, Marco; Brunetti, Maura; Casale, Federico; Moglia, Cristina; Calvo, Andrea; Marklund, Stefan L.; Andersen, Peter M.; Mora, Gabriele; Chio, Adriano

Mutant superoxide dismutase aggregates from human spinal cord transmit amyotrophic lateral sclerosis

ACTA NEUROPATHOLOGICA

IF9.3

2018-10-03

OAAI

Bidhendi, Elaheh Ekhtiari; Bergh, Johan; Zetterstrom, Per; Forsberg, Karin; Pakkenberg, Bente; Andersen, Peter M.; Marklund, Stefan L.; Brannstrom, Thomas

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis 散发性肌萎缩性侧索硬化症的错误折叠SOD1病理

SCIENTIFIC REPORTS

IF3.9

2018-09-21

110

OAAI

Pare, Bastien; Lehmann, Manuela; Beaudin, Marie; Nordstrom, Ulrika; Saikali, Stephan; Julien, Jean-Pierre; Gilthorpe, Jonathan D.; Marklund, Stefan L.; Cashman, Neil R.; Andersen, Peter M.; Forsberg, Karin; Dupre, Nicolas; Gould, Peter; Brannstrom, Thomas; Gros-Louis, Francois

Pyrimethamine Significantly Lowers Cerebrospinal Fluid Cu/Zn Superoxide Dismutase in Amyotrophic Lateral Sclerosis Patients with SOD1 Mutations

ANNALS OF NEUROLOGY

IF7.7

2017-06-09

OAAI

Lange, Dale J.; Shahbazi, Mona; Silani, Vincenzo; Ludolph, Albert C.; Weishaupt, Jochen H.; Ajroud-Driss, Senda; Fields, Kara G.; Remanan, Rahul; Appel, Stanley H.; Morelli, Claudia; Doretti, Alberto; Maderna, Luca; Messina, Stefano; Weiland, Ulrike; Marklund, Stefan L.; Andersen, Peter M.

Loss of miR-514a-3p regulation of PEG3 activates the NF-kappa B pathway in human testicular germ cell tumors

CELL DEATH & DISEASE

IF9.6

2017-05-04

OAAI

Ozata, Deniz Mahmut; Li, Xidan; Lee, Linkiat; Liu, Jikai; Warsito, Dudi; Hajeri, Praveensingh; Hultman, Isabell; Fotouhi, Omid; Marklund, Stefan; Ahrlund-Richter, Lars; Juhlin, Carl Christofer; Larsson, Catharina; Lui, Weng-Onn

Two superoxide dismutase prion strains transmit amyotrophic lateral sclerosis-like disease

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2016-05-03

OAAI

Bidhendi, Elaheh Ekhtiari; Bergh, Johan; Zetterstrom, Per; Andersen, Peter M.; Marklund, Stefan L.; Brannstrom, Thomas

NMR analysis of the CSF and plasma metabolome of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects

METABOLOMICS

IF3.3

2016-05-02

PREAI

Wu, Junfang; Wuolikainen, Anna; Trupp, Miles; Jonsson, Par; Marklund, Stefan L.; Andersen, Peter M.; Forsgren, Lars; Ohman, Anders