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Swi4-dependent SWI4 transcription couples cell size to cell cycle commitment Swi4依赖性SWI4转录将细胞大小与细胞周期决定耦合 Goswami, Pooja; Ghimire, Abhishek; Coffin, Carleton; Cheng, Jing; Coulombe-Huntington, Jasmin; Ghazal, Ghada; Thattikota, Yogitha; Guerra, Maria Florencia; Tyers, Mike; Tolllis, Sylvain; Royer, Catherine A. 分享 收藏
Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition Wilson, Gemma A.; Vuina, Karla; Sava, Georgina; Huard, Caroline; Meneguello, Leticia; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Maizels, Rory J.; Lauring, Josh; Kriston-Vizi, Janos; Tyers, Mike; Ali, Simak; Bertoli, Cosetta; de Bruin, Robertus A. M. 分享 收藏
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Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality Navare, Arti T.; Mast, Fred D.; Olivier, Jean Paul; Bertomeu, Thierry; Neal, Maxwell L.; Carpp, Lindsay N.; Kaushansky, Alexis; Coulombe-Huntington, Jasmin; Tyers, Mike; Aitchison, John D. 分享 收藏
Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia Krosl, Jana; Bordeleau, Marie-Eve; Moison, Celine; MacRae, Tara; Boivin, Isabel; Mayotte, Nadine; Gracias, Deanne; Baccelli, Irene; Lavallee, Vincent-Philippe; Bisaillon, Richard; Lehnertz, Bernhard; Mendoza-Sanchez, Rodrigo; Ruel, Rejean; Bertomeu, Thierry; Coulombe-Huntington, Jasmin; Boucher, Genevieve; Noronha, Nandita; Pabst, Caroline; Tyers, Mike; Gendron, Patrick; Lemieux, Sebastien; Barabe, Frederic; Marinier, Anne; Hebert, Josee; Sauvageau, Guy 分享 收藏
Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex St-Cyr, Daniel; Ceccarelli, Derek F.; Orlicky, Stephen; van der Sloot, Almer M.; Tang, Xiaojing; Kelso, Susan; Moore, Susan; James, Clint; Posternak, Ganna; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Marinier, Anne; Sicheri, Frank; Tyers, Mike 分享 收藏
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells Sohail, Muhammad; Shkreta, Lulzim; Toutant, Johanne; Rabea, Safwat; Babeu, Jean-Philippe; Huard, Caroline; Coulombe-Huntington, Jasmin; Delannoy, Aurelie; Placet, Morgane; Geha, Sameh; Gendron, Fernand-Pierre; Boudreau, Francois; Tyers, Mike; Grierson, David S.; Chabot, Benoit 分享 收藏
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition Benslimane, Yahya; Sanchez-Osuna, Maria; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Henry, Danielle; Huard, Caroline; Bonneil, Eric; Thibault, Pierre; Tyers, Mike; Harrington, Lea 分享 收藏
PRMT5 inhibition disrupts splicing and stemness in glioblastoma Sachamitr, Patty; Ho, Jolene C.; Ciamponi, Felipe E.; Ba-Alawi, Wail; Coutinho, Fiona J.; Guilhamon, Paul; Kushida, Michelle M.; Cavalli, Florence M. G.; Lee, Lilian; Rastegar, Naghmeh; Vu, Victoria; Sanchez-Osuna, Maria; Coulombe-Huntington, Jasmin; Kanshin, Evgeny; Whetstone, Heather; Durand, Mathieu; Thibault, Philippe; Hart, Kirsten; Mangos, Maria; Veyhl, Joseph; Chen, Wenjun; Tran, Nhat; Duong, Bang-Chi; Aman, Ahmed M.; Che, Xinghui; Lan, Xiaoyang; Whitley, Owen; Zaslaver, Olga; Barsyte-Lovejoy, Dalia; Richards, Laura M.; Restall, Ian; Caudy, Amy; Rost, Hannes L.; Bonday, Zahid Quyoom; Bernstein, Mark; Das, Sunit; Cusimano, Michael D.; Spears, Julian; Bader, Gary D.; Pugh, Trevor J.; Tyers, Mike; Lupien, Mathieu; Haibe-Kains, Benjamin; Luchman, H. Artee; Weiss, Samuel; Massirer, Katlin B.; Prinos, Panagiotis; Arrowsmith, Cheryl H.; Dirks, Peter B. 分享 收藏
UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex Chagraoui, Jalila; Girard, Simon; Spinella, Jean-Francois; Simon, Laura; Bonneil, Eric; Mayotte, Nadine; MacRae, Tara; Coulombe-Huntington, Jasmin; Bertomeu, Thierry; Moison, Celine; Tomellini, Elisa; Thibault, Pierre; Tyers, Mike; Marinier, Anne; Sauvageau, Guy 分享 收藏
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells Benslimane, Yahya; Bertomeu, Thierry; Coulombe-Huntington, Jasmin; McQuaid, Mary; Sanchez-Osuna, Maria; Papadopoli, David; Avizonis, Daina; Russo, Mariana De Sa Tavares; Huard, Caroline; Topisirovic, Ivan; Wurtele, Hugo; Tyers, Mike; Harrington, Lea 分享 收藏
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality Mast, Fred D.; Navare, Arti T.; van der Sloot, Almer M.; Coulombe-Huntington, Jasmin; Rout, Michael P.; Baliga, Nitin S.; Kaushansky, Alexis; Chait, Brian T.; Aderem, Alan; Rice, Charles M.; Sali, Andrej; Tyers, Mike; Aitchison, John D. 分享 收藏
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development Jacques, Samuel; van der Sloot, Almer M.; Huard, Caroline; Coulombe-Huntington, Jasmin; Tsao, Sarah; Tollis, Sylvain; Bertomeu, Thierry; Culp, Elizabeth J.; Pallant, Daniel; Cook, Michael A.; Bonneil, Eric; Thibault, Pierre; Wright, Gerard D.; Tyers, Mike 分享 收藏
Robust cullin-RING ligase function is established by a multiplicity of polyubiquitylation pathways Hill, Spencer; Reichermeier, Kurt; Scott, Daniel C.; Samentar, Lorena; Coulombe-Huntington, Jasmin; Izzi, Luisa; Tang, Xiaojing; Ibarra, Rebeca; Bertomeu, Thierry; Moradian, Annie; Sweredoski, Michael J.; Caberoy, Nora; Schulman, Brenda A.; Sicheri, Frank; Tyers, Mike; Kleiger, Gary 分享 收藏
The BioGRID interaction database: 2019 update BioGRID交互数据库: 2019更新 Oughtred, Rose; Stark, Chris; Breitkreutz, Bobby-Joe; Rust, Jennifer; Boucher, Lorrie; Chang, Christie; Kolas, Nadine; O'Donnell, Lara; Leung, Genie; McAdam, Rochelle; Zhang, Frederick; Dolma, Sonam; Willems, Andrew; Coulombe-Huntington, Jasmin; Chatr-aryamontri, Andrew; Dolinski, Kara; Tyers, Mike 分享 收藏
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Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer Li, Yongsheng; Sahni, Nidhi; Pancsa, Rita; McGrail, Daniel J.; Xu, Juan; Hua, Xu; Coulombe-Huntington, Jasmin; Ryan, Michael; Tychhon, Boranai; Sudhakar, Dhanistha; Hu, Limei; Tyers, Michael; Jiang, Xiaoqian; Lin, Shiaw-Yih; Babu, M. Madan; Yi, Song 分享 收藏
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