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G

Gunda I. Georg

university of minnesota

51H指数
619论文数
1.1W被引数
收录论文 262
发表时间
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Development of TSSK1 and TSSK2 Targeted Degraders Reveals Sperm Machinery for Protein Degradation and Potential for Nonhormonal Male Contraception靶向TSSK1和TSSK2降解剂的开发揭示了精子蛋白质降解机制及非激素男性避孕的潜力
errJournal of Medicinal Chemistry
IF6.8
err2026-06-02
err0
errOAAI
errJerrett A. Holdaway; Lokesh Saini; Raven Coil-Otto; Saman Nayyab; Mahboubeh Taghavi; Pablo Visconti; Gunda I. Georg
err分享
err收藏
LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet-Induced Ferroptosis, and These Effects are Enhanced by mTOR InhibitionLKB1丢失使肺肿瘤球体对米托坦诱导的铁死亡敏感，且这些效应被mTOR抑制增强
errMolecular Carcinogenesis
IF3.2
err2026-05-15
err0
errOAAI
errXueqing Liang; Ali Nakhi; Peter I. Dosa; Gunda I. Georg; Fekadu Kassie
err分享
err收藏
Development of a Second-Generation RARα Selective Antagonist as an Orally Bioavailable; Effective; Safe; and Reversible Male Contraceptive开发一种第二代RARα选择性拮抗剂作为口服生物利用度高、有效、安全且可逆的男性避孕药
errJournal of Medicinal Chemistry
IF6.8
err2026-05-11
err0
errOAAI
errRui Shi; Kristen John; Xuan Qin; Ehfazul Haque; Taimeng Liang; Narsihmulu Cheryala; Feng Li; Henry L. Wong; Gunda I. Georg
err分享
err收藏
Pharmacokinetic and Pharmacological Characterization of Novel Agmatine-Based Anti-hyperalgesic Compounds新型胍丁胺基抗超敏化化合物的药代动力学和药理学表征
errthe journal of pharmacology and experimental therapeutics
IF0
err2026-04-20
err0
PREAI
errBenjamin M. Clements; Cristina D. Peterson; Parker Jones; Kelley F. Kitto; Lukas D. Caye; Cecilia Barajas; Sudhakar R. Jakkaraj; Eyup Akgün; Gunda I. Georg; George L. Wilcox; Carolyn A. Fairbanks
err分享
err收藏
Structural Basis for BD1-Preferring 2; 4-Disubstituted Pyrimidine BRDT InhibitorsBD1-Preferring 2; 4-双取代嘧啶BRDT抑制剂的分子结构基础
errJournal of Medicinal Chemistry
IF6.8
err2026-04-15
err0
errOAAI
errTaimeng Liang; Xianghong Guan; Alice Chan; Prakriti Kalra; Rui Shi; Jonathan Solberg; Logan H. Sigua; Jun Qi; William C. K. Pomerantz; Ernst Schönbrunn; Jon E. Hawkinson; Gunda I. Georg
err分享
err收藏
Wee1-targeting inhibitors: From virtual screening to lead discoveryWee1靶向抑制剂：从虚拟筛选到先导化合物发现
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2026-03-31
err0
PREAI
errJochem Nelen; Bidisha Sarkar; Javier Jiménez-Bernad; Antonia C. Darragh; Andrew M. Hanna; Nicole B. Servant; Mirza Jahic; José Manuel Villalgordo-Soto; Gunda I. Georg; Horacio Pérez-Sánchez
err分享
err收藏
Correction to “From Discovery to Clinical Trial: YCT-529; an Oral NonHormonal Male Contraceptive Targeting the Retinoic Acid Receptor Alpha”更正：“从发现到临床试验：YCT-529；一种靶向视黄酸受体α的口服非激素男性避孕药”
errJournal of Medicinal Chemistry
IF6.8
err2026-03-03
err0
errOAAI
errRui Shi; Md Abdullah Al Noman; Nadja Mannowetz; Narsihmulu Cheryala; Ehfazul Haque; Noha Taher; Soma Maitra; Tahmina Naqvi; Sanny S. W. Chung; Akash Bakshi; Jon E. Hawkinson; Henry L. Wong; Debra J. Wolgemuth; Gunda I. Georg
err分享
err收藏
From Discovery to Clinical Trial: YCT-529, an Oral NonHormonal Male Contraceptive Targeting the Retinoic Acid Receptor Alpha
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2026-01-01
err0
PREAI
errShi, Rui; Al Noman, Md Abdullah; Mannowetz, Nadja; Cheryala, Narsihmulu; Haque, Ehfazul; Maitra, Soma; Naqvi, Tahmina; Chung, Sanny S. W.; Bakshi, Akash; Hawkinson, Jon E.; Wong, Henry L.; Wolgemuth, Debra J.; Georg, Gunda I.
err分享
err收藏
Progress towards a prodrug/enzyme intranasal delivery system for rapid prevention/reversal of seizure emergency开发一种前药/酶鼻内递送系统，以快速预防/逆转癫痫发作紧急情况
errJournal of Controlled Release
IF11.5
err2025-09-20
err0
PREAI
errRonald A. Siegel; Davin Rautiola; Narsihmulu Cheryala; Gunda I. Georg; James C. Cloyd
err分享
err收藏
From concept to the clinic: Retinoic acid receptor α antagonist YCT-529, an oral non-hormonal male contraceptive从概念到临床：视黄酸受体α拮抗剂YCT-529，一种口服非激素类男性避孕药
errAndrology
IF3.4
err2025-08-12
err0
PREAI
errNoha Taher; Ehfazul Haque; Gunda I. Georg
err分享
err收藏
Targeting the retinoid signaling pathway with YCT-529 for effective and reversible oral contraception in mice and primates
errCOMMUNICATIONS MEDICINE
IF6.3
err2025-03-13
err0
errOAAI
errMannowetz, Nadja; Chung, Sanny S. W.; Maitra, Soma; Noman, Md Abdullah Al; Wong, Henry L.; Cheryala, Narsihmulu; Bakshi, Akash; Wolgemuth, Debra J.; Georg, Gunda I.
err分享
err收藏
Targeting cyclin-dependent kinase 2 (CDK2) interactions with cyclins and Speedy 1 (Spy1) for cancer and male contraception
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-03-01
err0
PREAI
errGiarolla, Jeanine; Holdaway, Kelsey A.; Nazari, Maryam; Aiad, Laila; Sarkar, Bidisha; Georg, Gunda I.
err分享
err收藏
Development of the retinoic acid receptor alpha-specific antagonist YCT-529 for male contraception: A brief review维甲酸受体α特异性拮抗剂YCT-529的开发用于男性避孕：简要综述
errCONTRACEPTION
IF2.3
err2025-01-01
err0
errOAAI
errShi, Rui; Wolgemuth, Debra J.; Georg, Gunda I.
err分享
err收藏
Mechanisms of endocrine resistance to letrozole, fulvestrant, and palbociclib are associated with increased sensitivity to hexyl-cuban-1-yl biguanide inhibitors of CYP3A4 mediated epoxyeicosatrienoic acid biosynthesis
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errGuo, Zhijun; Lei, Jianxun; Makovec, Allison; Jayaraman, Swaathi; Hawse, John R.; Lange, Carol; Ambrose, Elizabeth; Georg, Gunda I.; D'Assoro, Tony; Matthew, Goetz P.; Potter, David A.
err分享
err收藏
Empowering Voices: Inspiring Women in Medicinal Chemistry
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-03-08
err0
errOAAI
errBlanco, Maria-Jesus; Bronson, Joanne J.; Dimauro, Erin F.; Dzierba, Carolyn; Eggen, Marijean; Garner, Amanda L.; Georg, Gunda; Giarolla, Jeanine; Goodwin, Nicole C.; Grenier-Davies, Melissa C.; Haskell-Luevano, Carrie; Holzgrabe, Ulrike; Huang, Rong; Lagiakos, H. Rachel; Leftheris, Katerina; Martin, Yvonne; Matos, Maria Joao; May-Dracka, Tricia L.; Muller, Christa E.; Newman, Amy H.; Parmee, Emma; Petter, Jennifer C.; Tamayo, Nuria A.; Wexler, Ruth R.; Bolognesi, Maria Laura; Ripka, Amy; Young, Wendy
err分享
err收藏
Empowering Voices: Inspiring Women in Medicinal Chemistry
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-03-08
err0
errOAAI
errBlanco, Maria-Jesus; Bronson, Joanne J.; DiMauro, Erin F.; Dzierba, Carolyn; Eggen, Marijean; Garner, Amanda L.; Georg, Gunda; Giarolla, Jeanine; Goodwin, Nicole C.; Grenier-Davies, Melissa C.; Haskell-Luevano, Carrie; Holzgrabe, Ulrike; Huang, Rong; Lagiakos, H. Rachel; Leftheris, Katerina; Martin, Yvonne; Matos, Maria Joao; May-Dracka, Tricia L.; Muller, Christa E.; Newman, Amy H.; Parmee, Emma; Petter, Jennifer C.; Tamayo, Nuria A.; Wexler, Ruth R.; Bolognesi, Maria Laura; Ripka, Amy; Young, Wendy
err分享
err收藏
Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-12-01
err4
errOAAI
errAl Noman, Md Abdullah; Cuellar, Rebecca A. D.; Kyzer, Jillian L.; Chung, Sanny S. W.; Cheryala, Narsihmulu; Holth, Trinh A. D.; Maitra, Soma; Naqvi, Tahmina; Wong, Henry L.; Schonbrunn, Ernst; Hawkinson, Jon E.; Wolgemuth, Debra J.; Georg, Gunda I.
err分享
err收藏
Patrick M. Woster Memorial Commentary
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-10-03
err0
PREAI
errRotella, David P.; Georg, Gunda
err分享
err收藏
Patrick M. Woster Memorial Commentary
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-09-08
err0
PREAI
errRotella, David P.; Georg, Gunda
err分享
err收藏
In Memory of Professor Hualiang Jiang纪念蒋华良教授
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-30
err0
PREAI
errDing, Ke; Wang, Shaomeng; Georg, Gunda; Portoghese, Philip; Lindsley, Craig
err分享
err收藏

研究方向

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