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A

Anke Unger

lead discovery center gmbh
H指数:16
被引数:1,401

个人简介

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荣誉奖项

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Design, Synthesis, and Structural Evolution of Pseudo-Natural Product IDO1 Inhibitors and Degraders

设计、合成及结构演化的伪天然产物IDO1抑制剂与降解剂的研制

Angewandte Chemie International Edition
IF16.9
2025-11-270
OAAI
Dr. Xiu-Fen Cheng; Dr. Belén Lucas; Dr. Philipp Lampe; Prof. Stefano Ugel; Dr. Suyuan Chen; Dr. Anke Unger; Dr. Matthias Bischoff; Dr. Soheila Rezaei Adariani; Dr. Kesava Reddy Naredla; Dr. Kamal Kumar; Annika Schmidt; Prof. Carsten Strohmann; Dr. Petra Janning; Dr. Raphael Gasper; Dr. María Lucas; Dr. Malte Gersch; Dr. Sonja Sievers; Prof. Vincenzo Bronte; Dr. Slava Ziegler; Prof. Herbert Waldmann
Highly potent quinoxalinediones inhibit a-hemolysin and ameliorate Staphylococcus aureus lung infections

高活性的喹喔啉二酮类化合物能够抑制α-溶血素并改善金黄色葡萄球菌肺部感染

CELL HOST & MICROBE
IF18.7
2025-04-011
OAAI
Shekhar, Aditya; Di Lucrezia, Raffaella; Jerye, Karoline; Korotkov, Vadim S.; Harmrolfs, Kirsten; Rox, Katharina; Weich, Herbert A.; Ghai, Ishan; Delhommel, Florent; Becher, Isabelle; Degenhart, Carsten; Fansa, Eyad; Unger, Anke; Habenberger, Peter; Klebl, Bert; Lukat, Peer; Schmelz, Stefan; Henke, Steffi; Borgert, Sebastian; Lang, Julia C.; Sasse, Florenz; Diestel, Randi; Richter, Clementine; Schneider-Daum, Nicole; Hinkelmann, Bettina; Niemz, Jana; Lehr, Claus-Michael; Jaensch, Lothar; Huehn, Jochen; Alm, Richard; Savitski, Mikhail; Welte, Tobias; Hesterkamp, Thomas; Sattler, Michael; Winterhalter, Mathias; Blankenfeldt, Wulf; Medina, Eva; Bilitewski, Ursula; Dinkel, Klaus; Broenstrup, Mark
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis

基于四唑哒嗪的小分子作为MACC1-driven肿瘤转移抑制剂的发现

BIOMEDICINE & PHARMACOTHERAPY
IF7.5
2023-12-013
OAAI
Yan, Shixian; Schoepe, Paul Curtis; Lewis, Joe; Putzker, Kerstin; Uhrig, Ulrike; Specker, Edgar; von Kries, Jens Peter; Lindemann, Peter; Omran, Anahid; Sanchez-Ibarra, Hector E.; Unger, Anke; Zischinsky, Mia-Lisa; Klebl, Bert; Walther, Wolfgang; Nazare, Marc; Kobelt, Dennis; Stein, Ulrike
Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety

通过具有外周活性的吗啡喃保护胰岛免受氧化细胞死亡，并增加药物安全性

MOLECULAR METABOLISM
IF6.6
2023-09-011
OAAI
Scholz, Okka; Huss, Elena; Otter, Silke; Herebian, Diran; Hamacher, Anna; Levy, Laura Mariana; Hristeva, Stanimira; Sanz, Miguel; Ajani, Haresh; Puentes, Alfredo Rodriguez; Hoffmann, Torsten; Hogeback, Jens; Unger, Anke; Terheyden, Susanne; do Fundo, Michelle Reina; Dewidar, Bedair; Roden, Michael; Lammert, Eckhard
Novel tetrazolopyridazine based MACC1 transcriptional inhibitors as promising anti-metastatic therapy

基于四唑哒嗪的新型MACC1转录抑制剂作为有希望的抗转移治疗

CANCER RESEARCH
IF16.6
2023-01-150
PRE
Schope, Paul Curtis; Yan, Shixian; Kobelt, Dennis; Lewis, Joe; Putzker, Kerstin; Uhrig, Ulrike; Specker, Edgar; von Kries, Jens Peter; Dahlmann, Mathias; Sanchez-Ibarra, Hector E.; Unger, Anke; Zischinsky, Mia-Lisa; Klebl, Bert; Lindemann, Peter; Walther, Wolfgang; Nazare, Marc; Stein, Ulrike
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-09-1513
PREAI
Lategahn, Jonas; Hardick, Julia; Grabe, Tobias; Niggenaber, Janina; Jeyakumar, Kirujan; Keul, Marina; Tumbrink, Hannah L.; Becker, Christian; Hodson, Luke; Kirschner, Tonia; Kloevekorn, Philip; Ketzer, Julia; Baumann, Matthias; Terheyden, Susanne; Unger, Anke; Weisner, Joern; Mueller, Matthias P.; van Otterlo, Willem A. L.; Bauer, Sebastian; Rauh, Daniel
Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer
CANCER RESEARCH
IF16.6
2019-05-0167
PREAI
Weisner, Joern; Landel, Ina; Reintjes, Christoph; Uhlenbrock, Niklas; Trajkovic-Arsic, Marija; Dienstbier, Niklas; Hardick, Julia; Ladigan, Swetlana; Lindemann, Marius; Smith, Steven; Quambusch, Lena; Scheinpflug, Rebekka; Depta, Laura; Gontla, Rajesh; Unger, Anke; Mueller, Heiko; Baumann, Matthias; Schultz-Fademrecht, Carsten; Guenther, Georgia; Maghnouj, Abdelouahid; Mueller, Matthias P.; Pohl, Michael; Teschendorf, Christian; Wolters, Heiner; Viebahn, Richard; Tannapfel, Andrea; Uhl, Waldemar; Hengstler, Jan G.; Hahn, Stephan A.; Siveke, Jens T.; Rauh, Daniel
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S
CHEMICAL SCIENCE
IF7.4
2019-01-0135
OAAI
Lategahn, Jonas; Keul, Marina; Kloevekorn, Philip; Tumbrink, Hannah L.; Niggenaber, Janina; Mueller, Matthias P.; Hodson, Luke; Flasshoff, Maren; Hardick, Julia; Grabe, Tobias; Engel, Julian; Schultz-Fademrecht, Carsten; Baumann, Matthias; Ketzer, Julia; Muehlenberg, Thomas; Hiller, Wolf; Guenther, Georgia; Unger, Anke; Mueller, Heiko; Heimsoeth, Alena; Golz, Christopher; Blank-Landeshammer, Bernhard; Kollipara, Laxmikanth; Zahedi, Rene P.; Strohmann, Carsten; Hengstler, Jan G.; van Otterlo, Willem A. L.; Bauer, Sebastian; Rauh, Daniel

研究方向

暂未获取到该数据
B
Bert Klebl
H 指数:34论文数:147被引数:6,391
D
Daniel Rauh
H 指数:56论文数:391被引数:1.3万
M
Matthias Baumann
H 指数:51论文数:258被引数:9,057
J
Jan Eickhoff
H 指数:24论文数:69被引数:3,037
C
Carsten Schultz‐Fademrecht
H 指数:23论文数:81被引数:2,462
J
Jan G. Hengstler
H 指数:94论文数:1,074被引数:3.4万
S
Sebastian Bauer
H 指数:70论文数:967被引数:2.6万
M
Marc Nazaré
H 指数:34论文数:184被引数:3,597
W
Wolfgang Walther
H 指数:44论文数:271被引数:6,265
B
Bård Helge Hoff
H 指数:26论文数:110被引数:1,716