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陈

陈小华 (Xiaohua Chen)

Chinese Academy of Sciences

48H指数
201论文数
8.5K被引数
收录论文 86
发表时间
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Advancing multi-subject text-to-image synthesis via Attention Refinement and Inheritance通过注意力精炼与继承推进多主体文本到图像合成
errKnowledge-Based Systems
IF7.6
err2026-08-03
err0
PREAI
errAn, Jinyang; Liu, Yisu; Zhang, Wanqian; Wang, Lin; Chen, Xiaohua; Yang, Zexian; Lin, Zheng; Wang, Weiping
err分享
err收藏
Genetically Encoded Lysine-Selective Photocyclization Enables Phage Display Selection of Cyclic Peptide Binders基因编码的赖氨酸选择性光环合作用实现了噬菌体展示筛选环状肽结合剂
errAngewandte Chemie International Edition
IF16.9
err2026-07-09
err0
PREAI
errXiao-Qin Yang; Wei Ming; Ze-Hao Zhang; Xiang Liu; Li-Wen Bai; Zheng-Hui Li; Rong Huang; Xiao-Hua Chen; Xinxiang Lei
err分享
err收藏
Multiplexed Photo-Cross-Linking Reveals Comprehensive Midnolin Interactome: Insights into Ubiquitin-Independent Degradation and Functional Diversity多重光交联揭示Midnolin互作组：对泛素非依赖性降解和功能多样性的见解
errJournal of the American Chemical Society
IF15.6
err2026-03-12
err0
PREAI
errYali Xu; Wensi Zhao; Jingjing Fu; Zihao Liu; Hui-Jun Nie; Jun Zhang; Jingli Guo; Minjia Tan; Xiao-Hua Chen
err分享
err收藏
The antibacterial mechanism and cell damage mechanism of natural antibacterial agents from different sources and their applications in food天然抗菌剂来源不同的抗菌机制和细胞损伤机制及其在食品中的应用
errJournal of Food Measurement and Characterization
IF3.3
err2025-11-24
err0
PREAI
errZaixiang Lou; Xu Cheng; Jiale Dong; Wenna Dai; Xiaohua Chen; Hongxin Wang
err分享
err收藏
Tau post-translational modifications in Alzheimer's disease: insights into pathogenesis, therapeutic strategies, and diagnostic advances阿尔茨海默病中tau的翻译后修饰：对发病机制、治疗策略和诊断进展的见解
errAgeing Research Reviews
IF12.4
err2025-10-24
err0
PREAI
errHuiwen Lei; Xiaohua Chen; Longzhu Ruan; Xuena Liu; Fei Ye; Kejing Li; Wei Cheng; Boyi Yu; Qiang Li; Cuixia Di
err分享
err收藏
Mechanisms of constitutive and agonist-induced 5-HT2B internalization, persistent endosomal signaling and paradoxical regulation of agonist pharmacology
errCELLULAR SIGNALLING
IF3.7
err2025-07-01
err0
PREAI
errGaidarov, Ibragim; Frazer, John; Chen, Xiaohua; Dang, Huong; Cordova, Isabel; Liaw, Chen; Sage, Carleton; Unett, David J.
err分享
err收藏
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells可见光控制的赖氨酸选择性交联技术解析蛋白质复合物和活细胞中的动态相互作用组
errAngewandte Chemie International Edition
IF0
err2025-06-18
err0
PREAI
errDr. Yali Xu; Dr. Hao Hu; Yu Ran; Dr. Wensi Zhao; Dr. An-Di Guo; Dr. Hui-Jun Nie; Dr. Linhui Zhai; Guang-Liang Yin; Jintao Cheng; Shengna Tao; Prof. Bing Yang; Prof. Minjia Tan; Prof. Xiao-Hua Chen
err分享
err收藏
Chemoproteomics reveals proteome-wide covalent and non-covalent targets of withaferin A化学生物组学揭示了姜黄素A在蛋白质组范围内的共价和非共价靶点。
errACTA PHARMACOLOGICA SINICA
IF8.4
err2025-02-03
err0
PREAI
errNie, HJ; Fu, YJ; Long, S; Wang, JY; Zhao, WS; Zhai, LH; Yang, YL; Tan, MJ; Hu, H; Chen, XH
err分享
err收藏
Investigating the frequency of neural autoantibodies in refractory focal epilepsy调查难治性局灶性癫痫中神经自身抗体的频率
errSEIZURE-EUROPEAN JOURNAL OF EPILEPSY
IF2.8
err2025-02-01
err0
PREAI
errGillinder, Lisa; Craig, Donald; Powell, Tamara; Walsh, Stephen; Phamnguyen, John; Wilson, Ian; Chen, Xiaohua; Gillis, David; Mccombe, Pamela
err分享
err收藏
Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library
errBIOCONJUGATE CHEMISTRY
IF3.9
err2024-08-08
err1
PREAI
errSuo, Yanrui; Li, Kaige; Ling, Xing; Yan, Kenian; Lu, Weiwei; Yue, Jinfeng; Chen, Xiaohua; Duan, Zhiqiang; Lu, Xiaojie
err分享
err收藏
A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy
errNATURE COMMUNICATIONS
IF15.7
err2024-08-04
err3
errOAAI
errGao, Jing; Jiang, Xingyu; Lei, Shumin; Cheng, Wenhao; Lai, Yi; Li, Min; Yang, Lei; Liu, Peifeng; Chen, Xiao-hua; Huang, Min; Yu, Haijun; Xu, Huixiong; Xu, Zhiai
err分享
err收藏
Direct detection of acetylcholinesterase by Fe(HCOO)2.6(OH)0.3. H2O nanosheets with oxidase-like activity on a smartphone platform
errTALANTA
IF6.1
err2024-07-01
err0
PREAI
errCao, Yongbin; Chen, Yuanyuan; Zhou, Yue; Chen, Xiaohua; Peng, Jian
err分享
err收藏
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-06-17
err0
PREAI
errWang, Wen-Jing; Gao, Lixin; Wang, Simei; Huang, Wensi; Meng, Xin-Yu; Hu, Hao; Chen, Ziqiang; Sun, Jingya; Yuan, Yali; Zhou, Yubo; Diao, Xingxing; Huang, Ruimin; Li, Jia; Chen, Xiao-Hua
err分享
err收藏
Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry
errADVANCED SCIENCE
IF14.1
err2024-04-30
err0
errOAAI
errYan, Ke-Nian; Nie, Yong-Qiang; Wang, Jia-Yu; Yin, Guang-Liang; Liu, Qia; Hu, Hao; Sun, Xiaoxia; Chen, Xiao-Hua
err分享
err收藏
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
errACTA PHARMACOLOGICA SINICA
IF8.4
err2024-04-12
err8
PREAI
errZou, Zhi-feng; Yang, Lei; Nie, Hui-jun; Gao, Jing; Lei, Shu-min; Lai, Yi; Zhang, Fan; Wagner, Ernst; Yu, Hai-jun; Chen, Xiao-hua; Xu, Zhi-ai
err分享
err收藏
Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells
errNATURE COMMUNICATIONS
IF15.7
err2024-02-17
err4
errOAAI
errHu, Hao; Hu, Wei; Guo, An-Di; Zhai, Linhui; Ma, Song; Nie, Hui-Jun; Zhou, Bin-Shan; Liu, Tianxian; Jia, Xinglong; Liu, Xing; Yao, Xuebiao; Tan, Minjia; Chen, Xiao-Hua
err分享
err收藏
The linkage misalignment of productive services and firms' domestic value-added ratio--Evidence from Chinese micro-firm data
errTECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
IF13.3
err2024-02-01
err3
PREAI
errZhang, Chonghui; Yuan, Lingjing; Yu, Xiao; Chen, Xiaohua
err分享
err收藏
Carrier systems of radiopharmaceuticals and the application in cancer therapy
errCELL DEATH DISCOVERY
IF7
err2024-01-09
err18
errOAAI
errZhang, Taotao; Lei, Huiwen; Chen, Xiaohua; Dou, Zhihui; Yu, Boyi; Su, Wei; Wang, Wei; Jin, Xiaodong; Katsube, Takanori; Wang, Bing; Zhang, Hong; Li, Qiang; Di, Cuixia
err分享
err收藏
Sensitive and rapid detection of bacterial endotoxin with a functional carbon nanotube field-effect transistor biosensor功能化碳纳米管场效应晶体管生物传感器灵敏快速检测细菌内毒素
errTALANTA
IF6.1
err2024-01-01
err7
PREAI
errCui, Qing; Li, Jiahao; Li, Yutao; Tang, Lina; Li, Kun; Li, Tingxian; Chen, Xiaohua; Zhang, Zhiyong; Zhang, Guo-Jun
err分享
err收藏
Multiomics analysis of metabolic heterogeneity in cervical cancer cell lines with or without HPV
errFRONTIERS IN ONCOLOGY
IF3.3
err2023-11-23
err1
errOAAI
errLiu, Xu; Zhu, Yaqi; Huang, Sheng; Shi, Tingyu; Li, Tanghua; Lan, Yanan; Cao, Xiaojian; Wu, Yingtao; Ding, Jinya; Chen, Xiaohua
err分享
err收藏

研究方向

药物化学化学生物学蛋白质相互作用和蛋白质稳态调控研究有机化学分子及细胞生物学蛋白质工程化学蛋白质组学蛋白质间相互作用和靶标确证研究靶向蛋白降解技术的创新药物研发活细胞中蛋白质相互作用工具箱蛋白质功能及靶标发现研究生物大分子靶向降解筛选技术难成药靶标小分子降解剂发现蛋白质稳态调控及其作用机制研究高效分子胶降解剂发现创新药物研究
合作学者
合作期刊
G
Gordon B. Mills
H 指数: 231 · 论文数: 3.5K
C
Chris Sander
H 指数: 191 · 论文数: 849
K
Kanyi Pu
H 指数: 131 · 论文数: 390
Y
Yiling Lu
H 指数: 129 · 论文数: 799
J
Joan S. Brugge
H 指数: 126 · 论文数: 597
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