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A

Anna M. Schmoker

Dana-Farber Cancer Institute
H指数:13
被引数:684

个人简介

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教育背景

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工作经历

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荣誉奖项

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RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor

MEK抑制剂的RAF异构体选择性及共价ARAF-MEK抑制剂的理性设计

Science Advances
IF12.5
2026-10-230
OAAI
Sayan Chakraborty; Jie Jiang; Javier Vinals Camallonga; Dimitris Gazgalis; Thomas W. Gero; Maurício T. Tavares; Georgia Dittemore; Emre Tkacik; Tyler S. Beyett; Dong Man Jang; Byung Hak Ha; Felix H. Gottlieb; Talya Levitz; Rebecca J. Metivier; Anna M. Schmoker; David A. Scott; Hyesung Jeon; Pasi A. Jänne; Michael J. Eck
A functional map of phosphoprotein phosphatase regulation identifies an evolutionarily conserved reductase for the catalytic metal ions

磷酸蛋白磷酸酶调控的功能图谱鉴定了一种进化上保守的催化金属离子还原酶

Nature Communications
IF15.7
2026-06-180
OAAI
Bob Meeusen; Sara M. Ambjørn; Jiri Veis; Rachel C. Riley; Gianmatteo Vit; Brooke L. Brauer; Mads H. Møller; Elora C. Greiner; Camilla B. Chan; Anna M. Schmoker; Blanca Lopez Mendez; Melanie B. Weisser; Dimitriya H. Garvanska; Hao Zhu; Norman E. Davey; Arminja N. Kettenbach; Egon Ogris; Jakob Nilsson
Metabolic rewiring driven by phosphoglycolate phosphatase deletion inhibits ferroptosis

磷酸甘油酸磷酸酶缺失驱动的代谢重编程抑制铁死亡

Science Advances
IF12.5
2026-05-290
OA
Marian Brenner; Sina Höhlein; Paul Wirth; Leon Neidt; Melina Lappe; Elisa Hopke; Eirini Sfakianaki; Martina Fischer; Kerstin Hadamek; Angelika Keller; Sebastian Bothe; José Pedro Friedmann Angeli; Anna M. Schmoker; Arminja N. Kettenbach; Agnes Fekete; Werner Schmitz; Ingrid Tessmer; Elisabeth Jeanclos; Antje Gohla
Characterization of Anti-Canine PD-1 Antibodies

抗犬PD-1抗体的表征

Cells
IF5.2
2026-05-230
OA
Colin J. Hartman; Petra Sergent; Anna Barbara Emilia Zimmermann; Olga R. Chávez-Alexander-Anderson; Luis A. Perez Alonso; Louise Lines; Juan Carlos Pinto-Cárdenas; Daniel Luna Dávalos; Anna M. Schmoker; Scott M. Palisoul; Johannes vom Berg; Xiaoxuan Ge; Jay L. Rothstein; Margaret E. Ackerman; Steven Fiering; Randolph J. Noelle; Hugo Arias-Pulido
Unveiling the hidden interactome of CRBN molecular glues

揭示CRBN分子胶的隐藏互作组

Nature Communications
IF15.7
2025-07-240
OAAI
Kheewoong Baek; Rebecca J. Metivier; Shourya S. Roy Burman; Jonathan W. Bushman; Hojong Yoon; Ryan J. Lumpkin; Julia K. Ryan; Dinah M. Abeja; Megha Lakshminarayan; Hong Yue; Samuel Ojeda; Yuan Xiong; Jianwei Che; Alyssa L. Verano; Anna M. Schmoker; Nathanael S. Gray; Katherine A. Donovan; Eric S. Fischer
Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues

DCAF16反式标记共价胶降解BRD4的可调性探索

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2024-12-013
OAAI
Hassan, Muhammad Murtaza; Li, Yen-Der; Ma, Michelle W.; Teng, Mingxing; Byun, Woong Sub; Puvar, Kedar; Lumpkin, Ryan; Sandoval, Brittany; Rutter, Justine C.; Jin, Cyrus Y.; Wang, Michelle Y.; Xu, Shawn; Schmoker, Anna M.; Cheong, Hakyung; Groendyke, Brian J.; Qi, Jun; Fischer, Eric S.; Ebert, Benjamin L.; Gray, Nathanael S.
Template-assisted covalent modification underlies activity of covalent molecular glues

模板辅助的共价修饰是共价分子胶活性的基础

NATURE CHEMICAL BIOLOGY
IF13.7
2024-07-295
OAAI
Li, Yen-Der; Ma, Michelle W.; Hassan, Muhammad Murtaza; Hunkeler, Moritz; Teng, Mingxing; Puvar, Kedar; Rutter, Justine C.; Lumpkin, Ryan J.; Sandoval, Brittany; Jin, Cyrus Y.; Schmoker, Anna M.; Ficarro, Scott B.; Cheong, Hakyung; Metivier, Rebecca J.; Wang, Michelle Y.; Xu, Shawn; Byun, Woong Sub; Groendyke, Brian J.; You, Inchul; Sigua, Logan H.; Tavares, Isidoro; Zou, Charles; Tsai, Jonathan M.; Park, Paul M. C.; Yoon, Hojong; Majewski, Felix C.; Sperling, Haniya T.; Marto, Jarrod A.; Qi, Jun; Nowak, Radoslaw P.; Donovan, Katherine A.; Slabicki, Mikolaj; Gray, Nathanael S.; Fischer, Eric S.; Ebert, Benjamin L.
Design of a Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-10-2018
OA
Wittlinger, Florian; Heppner, David E.; To, Ciric; Guenther, Marcel; Shin, Bo Hee; Rana, Jaimin K.; Schmoker, Anna M.; Beyett, Tyler S.; Berger, Lena M.; Berger, Benedict-Tilman; Bauer, Nicolas; Vasta, James D.; Corona, Cesear R.; Robers, Matthew B.; Knapp, Stefan; Janne, Pasi A.; Eck, Michael J.; Laufer, Stefan A.

研究方向

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M
Michael J. Eck
H 指数:89论文数:412被引数:4.7万
B
Bryan A. Ballif
H 指数:46论文数:146被引数:1.3万
H
Hyesung Jeon
H 指数:4论文数:18被引数:109
N
Nathanael S. Gray
H 指数:145论文数:1,469被引数:8.5万
E
Eric S. Fischer
H 指数:55论文数:281被引数:1.4万
A
Alicia M. Ebert
H 指数:14论文数:50被引数:547
P
Pasi A. Jänne
H 指数:163论文数:2,347被引数:12.6万
T
Tyler S. Beyett
H 指数:14论文数:64被引数:780
S
Shaun Rawson
H 指数:27论文数:83被引数:4,298
R
Ryan J. Lumpkin
H 指数:14论文数:31被引数:766