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Loss of aryl hydrocarbon receptor reduces pancreatic tumor growth by increasing immune cell infiltration Aryl hydrocarbon受体丢失通过增加免疫细胞浸润来减少胰腺肿瘤生长 Kannen, Vinicius; Olafsen, Ninni E.; Das, Siddhartha; Giuliana, Paolo; Izzati, Fauzia N.; Choksi, Hani; Ahrling, Samaneh S.; Cappello, Paola; Teino, Indrek; Maimets, Toivo; Jaudzems, Kristaps; Gulbinas, Antanas; Dambrauskas, Zilvinas; Edgar, Landon J.; Grant, Denis M.; Matthews, Jason 分享 收藏
Small-molecule inhibitor BAY synergizes with gemcitabine through AHR inhibition in pancreatic cancer cells Stukas, Darius; Zievyte, Inga; Ivanauskiene, Sandra; Karvelyte, Gabriele; Jasukaitiene, Aldona; Bartkeviciene, Arenida; Matthews, Jason; Maimets, Toivo; Teino, Indrek; Jaudzems, Kristaps; Gulbinas, Antanas; Dambrauskas, Zilvinas 分享 收藏
Loss of Parp7 increases type I interferon signalling and reduces pancreatic tumour growth by enhancing immune cell infiltration Kannen, Vinicius; Rasmussen, Marit; Das, Siddhartha; Giuliana, Paolo; Izzati, Fauzia N.; Choksi, Hani; Erlingsson, Linnea A. M.; Olafsen, Ninni E.; Ahrling, Samaneh S.; Cappello, Paola; Teino, Indrek; Maimets, Toivo; Jaudzems, Kristaps; Gulbinas, Antanas; Dambrauskas, Zilvinas; Edgar, Landon J.; Grant, Denis M.; Matthews, Jason 分享 收藏
Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX Vaskevicius, Aivaras; Baronas, Denis; Leitans, Janis; Kvietkauskaite, Agne; Ruksenaite, Audrone; Manakova, Elena; Toleikis, Zigmantas; Kaupinis, Algirdas; Kazaks, Andris; Gedgaudas, Marius; Mickeviciute, Aurelija; Juozapaitiene, Vaida; Schioeth, Helgi B.; Jaudzems, Kristaps; Valius, Mindaugas; Tars, Kaspars; Grazulis, Saulius; Meyer-Almes, Franz-Josef; Matuliene, Jurgita; Zubriene, Asta; Dudutiene, Virginija; Matulis, Daumantas 分享 收藏
Structural Basis for Inhibition of the SARS-CoV-2 nsp16 by Substrate-Based Dual Site Inhibitors Kalnins, Gints; Rudusa, Laura; Bula, Anna L.; Zelencova-Gopejenko, Diana; Bobileva, Olga; Sisovs, Mihails; Tars, Kaspars; Jirgensons, Aigars; Jaudzems, Kristaps; Bobrovs, Raitis 分享 收藏
Structural basis of epitope recognition by anti-alpha-synuclein antibodies MJFR14-6-4-2 Lieknina, Ilva; Reimer, Lasse; Panteejevs, Teodors; Lends, Alons; Jaudzems, Kristaps; El-Turabi, Aadil; Gram, Hjalte; Hammi, Anissa; Jensen, Poul Henning; Tars, Kaspars 分享 收藏
dGAE(297-391) Tau Fragment Promotes Formation of Chronic Traumatic Encephalopathy-Like Tau Filaments Kitoka, Kristine; Lends, Alons; Kucinskas, Gytis; Bula, Anna Lina; Krasauskas, Lukas; Smirnovas, Vytautas; Zilkova, Monika; Kovacech, Branislav; Skrabana, Rostislav; Hritz, Jozef; Jaudzems, Kristaps 分享 收藏
Biomimetic Spider Silk by Crosslinking and Functionalization with Multiarm Polyethylene Glycol 多臂聚乙二醇交联功能化仿生蜘蛛丝 Romanuks, Viktors; Fridmanis, Jekabs; Schmuck, Benjamin; Bula, Anna Lina; Lends, Alons; Senkane, Kristine; Leitis, Gundars; Gaidukovs, Sergejs; Smits, Krisjanis; Rising, Anna; Smits, Gints; Jaudzems, Kristaps 分享 收藏
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain Kumar, Rakesh; Le Marchand, Tanguy; Adam, Laurene; Bobrovs, Raitis; Chen, Gefei; Fridmanis, Jekabs; Kronqvist, Nina; Biverstal, Henrik; Jaudzems, Kristaps; Johansson, Jan; Pintacuda, Guido; Abelein, Axel 分享 收藏
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Discovery and optimisation of pyrazolo[1,5-a]pyrimidines as aryl hydrocarbon receptor antagonists Bobrovs, Raitis; Terentjeva, Svetlana; Olafsen, Ninni Elise; Dambrauskas, Zilvinas; Gulbinas, Antanas; Maimets, Toivo; Teino, Indrek; Jirgensons, Aigars; Matthews, Jason; Jaudzems, Kristaps 分享 收藏
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection Jalencas, Xavier; Berg, Hannes; Espeland, Ludvik Olai; Sreeramulu, Sridhar; Kinnen, Franziska; Richter, Christian; Georgiou, Charis; Yadrykhinsky, Vladyslav; Specker, Edgar; Jaudzems, Kristaps; Miletic, Tanja; Harmel, Robert; Gribbon, Phil; Schwalbe, Harald; Brenk, Ruth; Jirgensons, Aigars; Zaliani, Andrea; Mestres, Jordi 分享 收藏
Synthetic surfactant with a combined SP-B and SP-C analogue is efficient in rabbit models of adult and neonatal respiratory distress syndrome Mikolka, Pavol; Kronqvist, Nina; Haegerstrand-Bjorkman, Marie; Jaudzems, Kristaps; Kosutova, Petra; Kolomaznik, Maros; Saluri, Mihkel; Landreh, Michael; Calkovska, Andrea; Curstedt, Tore; Johansson, Jan 分享 收藏
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Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity Kovada, Vadims; Withers-Martinez, Chrislaine; Bobrovs, Raitis; Cerule, Helena; Liepins, Edgars; Grinberga, Solveiga; Hackett, Fiona; Collins, Christine R. R.; Kreicberga, Agrita; Jimenez-Diaz, Maria Belen; Angulo-Barturen, Inigo; Rasina, Dace; Suna, Edgars; Jaudzems, Kristaps; Blackman, Michael J.; Jirgensons, Aigars 分享 收藏
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