Chengkun Wu - Publications, H-index & Citations

Chengkun Wu

Nankai University

23H指数

134论文数

4.9K被引数

收录论文 45

发表时间

Pi4ka downregulation triggers Creb3l2-dependent lysosomal dysfunction to promote maladaptive tubular remodeling and immune activation in acute kidney injury Pi4ka下调触发Creb3l2依赖性的溶酶体功能障碍，以促进急性肾损伤中的不良管状重塑和免疫激活

Cell Death & Disease

IF9.6

2026-04-27

OAAI

Zhimin Chen; Jingzhi Xie; Chengkun Wu; Keng Ye; Yue Chen; Yankun Song; Huabin Ma; Jianfeng Wu; Li Chen; Yanfang Xu

Experimental study on the fluid-solid coupling effect of geosynthetic-reinforced calcareous sand revetment-breakwater 钙质砂土工合成材料加筋护岸-防波堤流固耦合效应的实验研究

Ocean Engineering

IF5.5

2026-03-02

PREAI

Chengkun Wu; Liang Lu; Haibo Zhu; Zongjian Wang; Katsuhiko Arai

Discovery of Capsazepine as a Novel MCL1 Inhibitor for Overcoming Tamoxifen Resistance in Breast Cancer Therapy 作为新型MCL1抑制剂，Capsazepine的发现：用于克服乳腺癌治疗中的他莫昔芬耐药性

eFood

IF5.7

2026-03-01

OAAI

Shujing Liu; Jiayin Li; Chengkun Wu; Yupeng Xiao; Jing Yu; Yu Xie; Chen Lin; Chunhua Liu; Yue Wang; Junfang Qin

A Neural Time-Series Learning Method for Accelerating Free-Energy Perturbation and Rare-Event Molecular Dynamics Simulations 基于神经网络的时序学习方法加速自由能扰动和稀有事件分子动力学模拟

Journal of Chemical Information and Modeling

IF5.3

2026-02-25

PREAI

Mengxia Mo; Haiyang Yu; Chengkun Wu; Zhijian Xu; Jie Liu; Wei-Qing Huang; Leyun Wu; Can Leng; Wangdong Yang; Kenli Li

Interfacial Field-Engineered Perovskite/Silicon Bipolar Photodiodes with Wavelength-Tunable Polarity for Dual-Channel Encrypted Optical Communication

Laser & Photonics Reviews

IF10

2026-02-06

PREAI

Wangyin Han; Wencan Wang; Shuai Zou; Chengkun Wu; Xiaodong Su; Wei Tian; Liang Li

CMD-FEP: Machine-Learned Free-Energy Prediction for Efficient Screening of Material Interfacial Binder Cmd-fep: 用于有效筛选材料界面粘合剂的机器学习自由能预测

Advanced Functional Materials

IF19

2026-01-19

PREAI

Mengxia Mo; Haiyang Yu; Xing Zhou; Wangdong Yang; Can Leng; Wei Zhou; Wei-Qing Huang; Chengkun Wu; Jie Liu

LAMBench: a benchmark for large atomistic models LAMBench：一种用于大型原子模型基准测试的工具

npj Computational Materials

IF11.9

2026-01-03

OAAI

Anyang Peng; Chun Cai; Mingyu Guo; Duo Zhang; Chengqian Zhang; Wanrun Jiang; Yinan Wang; Antoine Loew; Chengkun Wu; Weinan E; Linfeng Zhang; Han Wang

A fused deep learning approach to transform drug repositioning 一种融合深度学习的方法用于药物重定位

Communications Chemistry

IF6.2

2025-11-06

OAAI

Kun Li; Jiacai Yi; Qing Ye; Xixi Yang; Long Yu; YouChao Deng; Chengkun Wu; Tingjun Hou; Dejun Jiang; Dongsheng Cao

Melatonin Alleviates Retina Angiogenesis by Targeting Fibronectin and the VEGF Pathway 褪黑素通过靶向纤维连接蛋白和VEGF通路来缓解视网膜血管生成

FASEB JOURNAL

IF4.2

2025-09-30

PREAI

Chen, Fang; Yang, Xi; Yin, Yiwei; Meng, Zhishang; Wu, Ze; Liu, Dan; Wu, Chengkun; Luo, Jing; Wu, Wenyi

Decoding the Limits of Deep Learning in Molecular Docking for Drug Discovery 解析深度学习在分子对接药物发现中的局限

Chem. Sci.

IF7.4

2025-08-19

OAAI

Yue Li; Jia-Cai Yi; Hui Li; Kun Li; Fenghua Kang; Youchao Deng; Cheng-Kun Wu; Xiangzheng Fu; Dejun Jiang; Dongsheng Cao

Evidential deep learning-based drug-target interaction prediction 基于证据深度学习的药物-靶标相互作用预测

Nature Communications

IF15.7

2025-07-26

OAAI

Yanpeng Zhao; Yuting Xing; Yixin Zhang; Yifei Wang; Mengxuan Wan; Duoyun Yi; Chengkun Wu; Shangze Li; Huiyan Xu; Hongyang Zhang; Ziyi Liu; Guowei Zhou; Mengfan Li; Xuanze Wang; Zhengshan Chen; Ruijiang Li; Lianlian Wu; Dongsheng Zhao; Peng Zan; Song He; Xiaochen Bo

Pushing the boundaries of few-shot learning for low-data drug discovery with a Bayesian meta-learning hypernetwork framework 在贝叶斯元学习超网络框架下推动低数据药物发现中少样本学习的边界

BRIEFINGS IN BIOINFORMATICS

IF7.7

2025-07-01

PREAI

Yi, Jiacai; Jiang, Dejun; Wu, Chengkun; Zhang, Xiaochen; He, Weixing; Zhao, Wentao; Cao, Dongsheng

Ultrasmall platinum single-atom enzyme alleviates oxidative stress and macrophage polarization induced by acute kidney ischemia-reperfusion injury through inhibition of cell death storm 超小铂单原子酶通过抑制细胞死亡风暴，缓解急性肾缺血再灌注损伤引起的氧化应激和巨噬细胞极化。

JOURNAL OF NANOBIOTECHNOLOGY

IF12.6

2025-04-27

OAAI

Ye, Keng; Lin, Kongwen; Wu, Chengkun; Zou, Zhenhuan

Discovery of novel antimyeloma agents targeting TRIP13 by molecular modeling and bioassay 通过分子建模和生物测定发现靶向TRIP13的新型抗骨髓瘤药物

RSC MEDICINAL CHEMISTRY

IF3.6

2025-01-01

PREAI

Bunu, Samuel Jacob; Cai, Haiyan; Zhou, Zhaoyin; Zhang, Yanlei; Lai, Yue; Wang, Guanli; Song, Dongliang; Wu, Chengkun; Zheng, Hang; Xu, Zhijian; Shi, Jumei; Zhu, Weiliang

Exploring spatio-temporal dynamics for enhanced wind turbine condition monitoring

MECHANICAL SYSTEMS AND SIGNAL PROCESSING

IF8.9

2025-01-01

PREAI

Miao, Qiucheng; Wang, Dandan; Xia, Zongji; Xu, Chuanfu; Zhan, Jun; Wu, Chengkun

DDInter 2.0: an enhanced drug interaction resource with expanded data coverage, new interaction types, and improved user interface DDInter 2.0: 一个增强的药物相互作用资源，具有扩展的数据覆盖范围，新的相互作用类型和改进的用户界面

NUCLEIC ACIDS RESEARCH

IF13.1

2024-08-24

OAAI

Tian, Yao; Yi, Jiacai; Wang, Ningning; Wu, Chengkun; Peng, Jinfu; Liu, Shao; Yang, Guoping; Cao, Dongsheng

An Unsupervised Long- and Short-Term Sparse Graph Neural Network for Multisensor Anomaly Detection

IEEE SENSORS JOURNAL

IF4.5

2024-07-15

PREAI

Miao, Qiucheng; Wang, Dandan; Xu, Chuanfu; Zhan, Jun; Wu, Chengkun

ChemFH: an integrated tool for screening frequent false positives in chemical biology and drug discovery

NUCLEIC ACIDS RESEARCH

IF13.1

2024-05-23

OAAI

Shi, Shaohua; Fu, Li; Yi, Jiacai; Yang, Ziyi; Zhang, Xiaochen; Deng, Youchao; Wang, Wenxuan; Wu, Chengkun; Zhao, Wentao; Hou, Tingjun; Zeng, Xiangxiang; Lyu, Aiping; Cao, Dongsheng

Protein phosphorylation and kinases: Potential therapeutic targets in necroptosis

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2024-05-01

PREAI

Shi, Yihui; Wu, Chengkun; Shi, Jiayi; Gao, Taotao; Ma, Huabin; Li, Long; Zhao, Yufen

ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support

NUCLEIC ACIDS RESEARCH

IF13.1

2024-04-04

OAAI

Fu, Li; Shi, Shaohua; Yi, Jiacai; Wang, Ningning; He, Yuanhang; Wu, Zhenxing; Peng, Jinfu; Deng, Youchao; Wang, Wenxuan; Wu, Chengkun; Lyu, Aiping; Zeng, Xiangxiang; Zhao, Wentao; Hou, Tingjun; Cao, Dongsheng

研究方向