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LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment An, Disi; Chen, Guoying; Cheng, Wei-Yi; Mohrs, Katja; Adler, Christina; Gupta, Namita T.; Atwal, Gurinder S.; Dilillo, David J.; Daly, Christopher; Lin, John C.; Kuhnert, Frank 分享 收藏
A Tetravalent Bispecific Antibody Selectively Inhibits Diverse FGFR3 Oncogenic Variants Yang, Yan; Suhasini, Avvaru N.; Jiang, Zaoli; Liu, Nina; Rosconi, Michael; Zhang, Bojie; Li, Yinyin; Dudgeon, Drew; Seong, Changhyun; Kim, Steven; Rafique, Ashique; Huang, Tammy; Bhosle, Sangram; Krueger, Pamela; Ullman, Erica; Olson, William; Lin, John C.; Shen, Yang; Daly, Christopher 分享 收藏
A bispecific antibody inhibits FGFR3 dimerization and is highly effective in FGFR3-driven tumor models Yang, Yan; Avvaru, Naga Suhasini; Jiang, Zaoli; Liu, Nina; Rosconi, Michael; Zhang, Bojie; Li, Yinyin; Ullman, Erica; Lin, John Chia-Yang; Shen, Yang; Daly, Christopher 分享 收藏
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IL-6-GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models Carbonaro, Marisa; Wang, Kehui; Huang, Hui; Frleta, Davor; Patel, Aditi; Pennington, Alexander; Desclaux, Mathieu; Moller-Tank, Sven; Grindley, Justin; Altarejos, Judith; Zhong, Jun; Polites, Greg; Poueymirou, William; Jaspers, Stephen; Kyratsous, Christos; Zambrowicz, Brian; Murphy, Andrew; Lin, John C.; Macdonald, Lynn E.; Daly, Christopher; Sleeman, Mark; Thurston, Gavin; Li, Zhe 分享 收藏
Boosting anti-tumor immunity by promoting high endothelial venule and tertiary lymphoid structure formation in solid tumors via LTBR agonism An, Disi; Chen, Guoying; Wang, Wei; Mohrs, Katja; DiLillo, David; Daly, Christopher; Thurston, Gavin; Lin, John; Gupta, Namita; Atwal, Mickey; Kuhnert, Frank 分享 收藏
Development of novel human hepatocellular carcinoma models using genetically modified human hepatocytes in FSRG humanized liver mice Carbonaro, Marisa; Bonetti, Ciro; Huang, Hui; Wang, Kehui; Desclaux, Mathieu; Gong, Guochun; Lin, John C.; Daly, Christopher; Thurston, Gavin; Li, Zhe 分享 收藏
A Bispecific METxMET Antibody-Drug Conjugate with Cleavable Linker Is Processed in Recycling and Late Endosomes Bay, Andres E. Perez; Faulkner, Devon; DaSilva, John O.; Young, Tara M.; Yang, Katie; Giurleo, Jason T.; Ma, Dangshe; Delfino, Frank J.; Olson, William C.; Thurston, Gavin; Daly, Christopher; Andreev, Julian 分享 收藏
Preclinical Study of a Biparatopic METxMET Antibody-Drug Conjugate, REGN5093-M114, Overcomes MET-driven Acquired Resistance to EGFR TKIs in EGFR-mutant NSCLC 双互补位METxMET抗体-药物偶联物的临床前研究REGN5093-M114克服了EGFR突变的NSCLC中MET驱动的对EGFR TKIs的获得性耐药性 Oh, Seung Yeon; Lee, You Won; Lee, Eun Ji; Kim, Jae Hwan; Park, YoungJoon; Heo, Seong Gu; Yu, Mi Ra; Hong, Min Hee; DaSilva, John; Daly, Christopher; Cho, Byoung Chul; Lim, Sun Min; Yun, Mi Ran 分享 收藏
A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade DaSilva, John O.; Yang, Katie; Surriga, Oliver; Nittoli, Thomas; Kunz, Arthur; Franklin, Matthew C.; Delfino, Frank J.; Mao, Shu; Zhao, Feng; Giurleo, Jason T.; Kelly, Marcus P.; Makonnen, Sosina; Hickey, Carlos; Krueger, Pamela; Foster, Randi; Chen, Zhaoyuan; Retter, Marc W.; Slim, Rabih; Young, Tara M.; Olson, William C.; Thurston, Gavin; Daly, Christopher 分享 收藏
Improving Evidence-Based Non-Accidental Trauma Screening in a Pediatric Emergency Department Appenteng, Roselyn; Williams, Heather; Fain, Emily; Frazier, Barron; Daly, Christopher; Phillips, Alisa; Boudreaux, Danielle; Greeno, Amber; Danko, Melissa; Johnson, David P. 分享 收藏
Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function Fgf15/FGF19的单体/二聚体形式在肝细胞增殖和代谢功能中显示出不同的活性 Williams, Courtney M.; Calderon, Jessica Harper; Hock, E.; Jimenez, Yasalp; Barringer, Kevin; Carbonaro, Marisa; Molina-Portela, Maria del Pilar; Thurston, Gavin; Li, Zhe; Daly, Christopher 分享 收藏
Autophagy protects tumors from T cell-mediated cytotoxicity via inhibition of TNFα-induced apoptosis Young, Tara M.; Reyes, Claudia; Pasnikowski, Elizabeth; Castanaro, Carla; Wong, Chung; Decker, Corinne E.; Chiu, Joyce; Song, Hang; Wei, Yi; Bai, Yu; Zambrowicz, Brian; Thurston, Gavin; Daly, Christopher 分享 收藏
A biparatopic HER2xHER2 antibody drug conjugate with potent ant-itumor activity Bay, Andres Perez; Faulkner, Devon; Tiwari, Shiwani; Castanaro, Carla; Zheng, Xiang; Kunz, Arthur; Nittoli, Thomas; Han, Amy; Olson, William; Thurston, Gavin; Daly, Christopher; Andreev, Julian 分享 收藏
Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy Waite, Janelle C.; Wang, Bei; Haber, Lauric; Hermann, Aynur; Ullman, Erica; Ye, Xuan; Dudgeon, Drew; Slim, Rabih; Ajithdoss, Dharani K.; Godin, Stephen J.; Ramos, Ilyssa; Wu, Qi; Oswald, Erin; Poon, Patrick; Golubov, Jacquelynn; Grote, Devon; Stella, Jennifer; Pawashe, Arpita; Finney, Jennifer; Herlihy, Evan; Ahmed, Hassan; Kamat, Vishal; Dorvilliers, Amanda; Navarro, Elizabeth; Xiao, Jenny; Kim, Julie; Yang, Shao Ning; Warsaw, Jacqueline; Lett, Clarissa; Canova, Lauren; Schulenburg, Teresa; Foster, Randi; Krueger, Pamela; Garnova, Elena; Rafique, Ashique; Babb, Robert; Chen, Gang; Oristian, Nicole Stokes; Siao, Chia-Jen; Daly, Christopher; Gurer, Cagan; Martin, Joel; Macdonald, Lynn; MacDonald, Douglas; Poueymirou, William; Smith, Eric; Lowy, Israel; Thurston, Gavin; Olson, William; Lin, John C.; Sleeman, Matthew A.; Yancopoulos, George D.; Murphy, Andrew J.; Skokos, Dimitris 分享 收藏
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Bispecific HER2 ADC: Making more potent HER2 ADC by improving target internalization Bay, Andres Perez; Kalsy, Anuj; Tiwari, Shiwani; Luan, Bo; Kunz, Art; Chen, Zhaoyuan; Zhang, Li; Potocky, Terra; Nittoli, Thomas; Thurston, Gavin; Daly, Christopher; Andreev, Julian 分享 收藏
Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor Daly, Christopher; Qian, Xiaozhong; Castanaro, Carla; Pasnikowskil, Elizabeth; Jiang, Xiabo; Thomson, Benjamin R.; Quaggin, Susan E.; Papadopoulos, Nicholas; Wei, Yang; Rudge, John S.; Thurston, Gavin; Yancopoulos, George D.; Davis, Samuel 分享 收藏
Bispecific Antibodies and Antibody-Drug Conjugates (ADCs) Bridging HER2 and Prolactin Receptor Improve Efficacy of HER2 ADCs Andreev, Julian; Thambi, Nithya; Bay, Andres E. Perez; Delfino, Frank; Martin, Joel; Kelly, Marcus P.; Kirshner, Jessica R.; Rafique, Ashique; Kunz, Arthur; Nittoli, Thomas; MacDonald, Douglas; Daly, Christopher; Olson, William; Thurston, Gavin 分享 收藏
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