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B

B. Chevalier

institut necker enfants malades
H指数:24
被引数:2,140

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Beyond Trikafta: new models to assess tissue dependent rescue of N1303K-CFTR

超越Trikafta：评估组织依赖性N1303K-CFTR挽救的新模型

Frontiers in Pharmacology
IF4.8
2025-10-290
OAAI
Iwona Pranke†; Valeria Capurro†; Benoit Chevalier†; Emanuela Pesce†; Valeria Tomati; Cristina Pastorino; Mairead Kelly-Aubert; Aurelie Hatton; Elise Dreano; Mariateresa Lena; Renata Bocciardi; Federico Zara; Stefano Pantano; Vito Terlizzi; Cristina Lucanto; Stefano Costa; Laura Claut; Valeria Daccò; Piercarlo Poli; Massimo Maschio; Benedetta Fabrizzi; Nicole Caporelli; Marco Cipolli; Sonia Volpi; Frederique Chedevergne; Laure Cosson; Julie Macey; Sophie Ramel; Laurence Weiss; Dominique Grenet; Laurence Le Clainche-Viala; Benoit Douvry; Bruno Ravoninjatovo; Camille Audousset; Aurélie Tatopoulos; Bénédicte Richaud-Thiriez; Melissa Baravalle; Guillaume Thouvenin; Guillaume Labbé; Marie Mittaine; Philippe Reix; Isabelle Durieu; Julie Mankikian; Stéphanie Bui; Thao Nguyen-Khoa; Karim Khoukh; Clémence Martin; Jennifer Da Silva; Paola De Carli; Carlo Castellani; Federico Cresta; Luis Galietta; Anne Guillemaut; Emmanuelle Girodon; Natacha Remus; Mathis Bulcaen; Marjolein Ensinck; Miroslaw Zajac; Marianne Carlon; Jean LeBihan; Pierre-Régis Burgel; Isabelle Sermet-Gaudelus‡; Alexandre Hinzpeter‡; Nicoletta Pedemonte‡
In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators

在体内外及细胞外对位于第四细胞内环的囊性纤维化跨膜电导调节因子致病性变异进行表征及其通过调节剂的修复

British Journal of Pharmacology
IF7.7
2025-08-200
OAAI
Emanuela Pesce; Valeria Tomati; Valeria Capurro; Mariateresa Lena; Cristina Pastorino; Miro Astore; Serdar Kuyucak; Benoit Chevalier; Elvira Sondo; Federico Cresta; Alice Dighero; Vito Terlizzi; Cristina Fevola; Stefano Costa; Maria Cristina Lucanto; Valeria Daccò; Laura Claut; Francesca Ficili; Benedetta Fabrizzi; Renata Bocciardi; Federico Zara; Carlo Castellani; Luis J. V. Galietta; Shafagh A. Waters; Alexandre Hinzpeter; Nicoletta Pedemonte
Role of KCNK3 Dysfunction in Dasatinib-associated Pulmonary Arterial Hypertension and Endothelial Cell Dysfunction

KCNK3功能障碍在达沙替尼相关肺动脉高压和内皮细胞功能障碍中的作用

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
IF5.3
2024-07-012
PRE
Le Ribeuz, Helene; Willer, Anais Saint-Martin; Chevalier, Benoit; Sancho, Maria; Masson, Bastien; Eyries, Melanie; Jung, Vincent; Guerrera, Ida Chiara; Dutheil, Mary; El Jekmek, Kristelle; Laubry, Loann; Carpentier, Gilles; Perez-Vizcaino, Francisco; Tu, Ly; Guignabert, Christophe; Chaumais, Marie-Camille; Pechoux, Christine; Humbert, Marc; Hinzpeter, Alexandre; Mercier, Olaf; Capuano, Veronique; Montani, David; Antigny, Fabrice
Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
CELL REPORTS MEDICINE
IF10.6
2024-05-015
OAAI
Bulcaen, Mattijs; Kortleven, Pheline; Liu, Ronald B.; Maule, Giulia; Dreano, Elise; Kelly, Mairead; Ensinck, Marjolein M.; Thierie, Sam; Smits, Maxime; Ciciani, Matteo; Hatton, Aurelie; Chevalier, Benoit; Ramalho, Anabela S.; Solvas, Xavier Casadevall i; Debyser, Zeger; Vermeulen, Francois; Gijsbers, Rik; Sermet-Gaudelus, Isabelle; Cereseto, Anna; Carlon, Marianne S.
Nonsense mutations accelerate lung disease and decrease survival of cystic fibrosis children
JOURNAL OF CYSTIC FIBROSIS
IF6
2023-11-011
PRE
Orenti, Annalisa; Pranke, Iwona; Faucon, Caroline; Varilh, Jessica; Hatton, Aurelie; Golec, Anita; Dehillotte, Clemence; Durieu, Isabelle; Reix, Philippe; Burgel, Pierre-Regis; Grenet, Dominique; Tasset, Celine; Gachelin, Elsa; Perisson, Caroline; Lepissier, Agathe; Dreano, Elise; Tondelier, Danielle; Chevalier, Benoit; Weiss, Laurence; Kiefer, Sebastien; Laurans, Muriel; Chiron, Raphael; Lemonnier, Lydie; Marguet, Christophe; Jung, Andreas; Edelman, Aleksander; Kerem, Bat-Sheva; Girodon, Emmanuelle; Taulan-Cadars, Magali; Hinzpeter, Alexandre; Kerem, Eitan; Naehrlich, Lutz; Sermet-Gaudelus, Isabelle
Theratyping cystic fibrosis patients to guide elexacaftor/ tezacaftor/ivacaftor out-of-label prescription
EUROPEAN RESPIRATORY JOURNAL
IF21
2023-09-1133
PRE
Dreano, Elise; Burgel, Pierre Regis; Hatton, Aurelie; Bouazza, Naim; Chevalier, Benoit; Macey, Julie; Leroy, Sylvie; Durieu, Isabelle; Weiss, Laurence; Grenet, Dominique; Stremler, Nathalie; Ohlmann, Camille; Reix, Philippe; Porzio, Michele; Claude, Pauline Roux; Remus, Natacha; Douvry, Benoit; Montcouquiol, Sylvie; Cosson, Laure; Mankikian, Julie; Languepin, Jeanne; Houdouin, Veronique; Le Clainche, Laurence; Guillaumot, Anne; Pouradier, Delphine; Tissot, Adrien; Priou, Pascaline; Mely, Laurent; Chedevergne, Frederique; Lebourgeois, Muriel; Lebihan, Jean; Martin, Clemence; Zavala, Flora; Da Silva, Jennifer; Lemonnier, Lydie; Kelly-Aubert, Mairead; Golec, Anita; Foucaud, Pierre; Marguet, Christophe; Edelman, Aleksander; Hinzpeter, Alexandre; de Carli, Paola; Girodon, Emmanuelle; Sermet-Gaudelus, Isabelle; Pranke, Iwona
Keratin 8 is a scaffolding and regulatory protein of ERAD complexes
CELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
2022-09-013
OA
Pranke, Iwona Maria; Chevalier, Benoit; Premchandar, Aiswarya; Baatallah, Nesrine; Tomaszewski, Kamil F.; Bitam, Sara; Tondelier, Danielle; Golec, Anita; Stolk, Jan; Lukacs, Gergely L.; Hiemstra, Pieter S.; Dadlez, Michal; Lomas, David A.; Irving, James A.; Delaunay-Moisan, Agnes; van Anken, Eelco; Hinzpeter, Alexandre; Sermet-Gaudelus, Isabelle; Edelman, Aleksander
Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR

药理学伴侣通过不同的结合位点改善域内稳定性和域间组装，以挽救错误折叠的CFTR

CELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
2021-10-2938
OA
Baatallah, Nesrine; Elbahnsi, Ahmad; Mornon, Jean-Paul; Chevalier, Benoit; Pranke, Iwona; Servel, Nathalie; Zelli, Renaud; Decout, Jean-Luc; Edelman, Aleksander; Sermet-Gaudelus, Isabelle; Callebaut, Isabelle; Hinzpeter, Alexandre
New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation (vol 11, 6842, 2021)
SCIENTIFIC REPORTS
IF3.9
2021-09-150
OAAI
Bitam, Sara; Elbahnsi, Ahmad; Creste, Geordie; Pranke, Iwona; Chevalier, Benoit; Berhal, Farouk; Hoffmann, Brice; Servel, Nathalie; Baatalah, Nesrine; Tondelier, Danielle; Hatton, Aurelie; Moquereau, Christelle; Faria Da Cunha, Melanie; Pastor, Alexandra; Lepissier, Agathe; Hinzpeter, Alexandre; Mornon, Jean-Paul; Prestat, Guillaume; Edelman, Aleksander; Callebaut, Isabelle; Gravier-Pelletier, Christine; Sermet-Gaudelus, Isabelle
New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation
SCIENTIFIC REPORTS
IF3.9
2021-03-2510
OAAI
Bitam, Sara; Elbahnsi, Ahmad; Creste, Geordie; Pranke, Iwona; Chevalier, Benoit; Berhal, Farouk; Hoffmann, Brice; Servel, Nathalie; Tondelier, Danielle; Hatton, Aurelie; Moquereau, Christelle; Da Cunha, Melanie Faria; Pastor, Alexandra; Lepissier, Agathe; Hinzpeter, Alexandre; Mornon, Jean-Paul; Prestat, Guillaume; Edelman, Aleksander; Callebaut, Isabelle; Gravier-Pelletier, Christine; Sermet-Gaudelus, Isabelle
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2020-03-0110
OAAI
Froux, Lionel; Elbahnsi, Ahmad; Boucherle, Benjamin; Billet, Arnaud; Baatallah, Nesrine; Hoffmann, Brice; Alliot, Julien; Zelli, Renaud; Zeinyeh, Wael; Haudecoeur, Romain; Chevalier, Benoit; Fortune, Antoine; Mirval, Sandra; Simard, Christophe; Lehn, Pierre; Mornon, Jean-Paul; Hinzpeter, Alexandre; Becq, Frederic; Callebaut, Isabelle; Decout, Jean-Luc

研究方向

暂未获取到该数据
A
Alexandre Hinzpeter
H 指数:25论文数:92被引数:1,916
I
Isabelle Sermet‐Gaudelus
H 指数:65论文数:530被引数:1.8万
I
Iwona Pranke
H 指数:18论文数:60被引数:1,341
A
Aleksander Edelman
H 指数:49论文数:217被引数:6,122
P
Pascal Barbry
H 指数:73论文数:323被引数:2.1万
B
Brice Marcet
H 指数:20论文数:44被引数:2,070
A
Aurélie Hatton
H 指数:20论文数:63被引数:1,709
I
Isabelle Callebaut
H 指数:73论文数:388被引数:1.9万
N
Nesrine Baatallah
H 指数:8论文数:18被引数:343
E
Emmanuelle Girodon
H 指数:30论文数:115被引数:3,627