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J

Jean-Louis Mergny

Centre National de la Recherche Scientifique
H指数:82
被引数:2.7万

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G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing

G-四链体是调控核小体排除和RNA聚合酶II暂停的启动子元件。

Nature Genetics
IF0
2025-07-220
PRE
Cyril Esnault; Amal Zine El Aabidine; Marie-Cécile Robert; Anne Cucchiarini; Talha Magat; Alexia Pigeot; Soumya Bouchouika; Encar Garcia-Oliver; Kevin Gawron; Eugénia Basyuk; Magdalena A. Karpinska; Alja Kozulic-Pirher; Yu Luo; Daniela Verga; Raphael Mourad; Ovidiu Radulescu; Jean-Louis Mergny; Edouard Bertrand; Jean-Christophe Andrau
Lysosomal membrane permeabilization enhances the anticancer effects of POLR1 (RNA polymerase I) transcription inhibitors

溶酶体膜通透性增强可提高POLR1（RNA聚合酶I）转录抑制剂的抗癌效果

Autophagy
IF14.3
2025-06-180
PRE
Lucille Ferret; Jonathan G. Pol; Allan Sauvat; Gautier Stoll; Karla Alvarez-Valadez; Alexandra Muller; Julie Le Naour; Felix Peyre; Gerasimos Anagnostopoulos; Isabelle Martins; Maria Chiara Maiuri; Harald Wodrich; Lionel Guittat; Jean-Louis Mergny; Guido Kroemer; Mojgan Djavaheri-Mergny
Design, synthesis, biophysical and biological evaluation of original condensed pyrrolopyrimidine and pyrrolopyridine ligands as anti-SARS-CoV-2 agents targeting G4

原始稠合吡咯并嘧啶和吡咯并吡啶配体的设计、合成及其作为靶向G4的抗SARS-CoV-2剂的生物物理和生物学评价

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2025-05-100
OAAI
Guillon, Jean; Savrimoutou, Solene; Da Rocha, Nicolas; Albenque-Rubio, Sandra; Helynck, Olivier; Durand, Cyrielle; Chiaravalli, Jeanne; Pinaud, Noel; Ronga, Luisa; Moreau, Stephane; Chirold, Simon; Zangmo, Tshering; Arab, Melika; Lari, Lindita; Mergny, Jean-Louis; Munier-Lehmann, Helene; Lavigne, Marc

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周俊
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