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Vinculin-Arp2/3 interaction inhibits branched actin assembly to control migration and proliferation James, John; Fokin, Artem, I; Guschin, Dmitry Y.; Wang, Hong; Polesskaya, Anna; Rubtsova, Svetlana N.; Clainche, Christophe Le; Silberzan, Pascal; Gautreau, Alexis M.; Romero, Stephane 分享 收藏
A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses Kohlhuber, F; Rogers, NC; Watling, D; Feng, J; Guschin, D; Briscoe, J; Witthuhn, BA; Kotenko, SV; Pestka, S; Stark, GR; Ihle, JN; Kerr, IM 分享 收藏
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease Zeitler, Bryan; Froelich, Steven; Marlen, Kimberly; Shivak, David A.; Yu, Qi; Li, Davis; Pearl, Jocelynn R.; Miller, Jeffrey C.; Zhang, Lei; Paschon, David E.; Hinkley, Sarah J.; Ankoudinova, Irina; Lam, Stephen; Guschin, Dmitry; Kopan, Lexi; Cherone, Jennifer M.; Nguyen, Hoang-Oanh B.; Qiao, Guijuan; Ataei, Yasaman; Mendel, Matthew C.; Amora, Rainier; Surosky, Richard; Laganiere, Josee; Vu, B. Joseph; Narayanan, Anand; Sedaghat, Yalda; Tillack, Karsten; Thiede, Christina; Gaertner, Annette; Kwak, Seung; Bard, Jonathan; Mrzljak, Ladislav; Park, Larry; Heikkinen, Taneli; Lehtimaki, Kimmo K.; Svedberg, Marie M.; Haggkvist, Jenny; Tari, Lenke; Toth, Miklos; Varrone, Andrea; Halldin, Christer; Kudwa, Andrea E.; Ramboz, Sylvie; Day, Michelle; Kondapalli, Jyothisri; Surmeier, D. James; Urnov, Fyodor D.; Gregory, Philip D.; Rebar, Edward J.; Munoz-Sanjuan, Ignacio; Zhang, H. Steve 分享 收藏
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins Bulanova, Daria; Ianevski, Aleksandr; Bugai, Andrii; Akimov, Yevhen; Kuivanen, Suvi; Paavilainen, Henrik; Kakkola, Laura; Nandania, Jatin; Turunen, Laura; Ohman, Tiina; Ala-Hongisto, Hanna; Pesonen, Hanna M.; Kuisma, Marika S.; Honkimaa, Anni; Walton, Emma L.; Oksenych, Valentyn; Lorey, Martina B.; Guschin, Dmitry; Shim, Jungmin; Kim, Jinhee; Than, Thoa T.; Chang, So Young; Hukkanen, Veijo; Kulesskiy, Evgeny; Marjomaki, Varpu S.; Julkunen, Ilkka; Nyman, Tuula A.; Matikainen, Sampsa; Saarela, Jani S.; Sane, Famara; Hober, Didier; Gabriel, Guelsah; De Brabander, Jef K.; Martikainen, Miika; Windisch, Marc P.; Min, Ji-Young; Bruzzone, Roberto; Aittokallio, Tero; Vaha-Koskela, Markus; Vapalahti, Olli; Pulk, Arto; Velagapudi, Vidya; Kainov, Denis E. 分享 收藏
Towards Clinical Translation of Hematopoietic Stem Cell Gene Editing for the Correction of SCID-X1 Mutations Genovese, Pietro; Schiroli, Giulia; Conway, Anthony; Ferrari, Samuele; Guschin, Dmitry Y.; Di Tomaso, Tiziano; Albano, Luisa; Marin, Virna; Giuliani, Erica; Gregory, Philip D.; Holmes, Michael C.; Gentner, Bernhard; Bovolenta, Chiara; Cost, Gregory J.; Lombardo, Angelo; Naldini, Luigi 分享 收藏
Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma Beane, Joal D.; Lee, Gary; Zheng, Zhili; Mendel, Matthew; Abate-Daga, Daniel; Bharathan, Mini; Black, Mary; Gandhi, Nimisha; Yu, Zhiya; Chandran, Smita; Giedlin, Martin; Ando, Dale; Miller, Jeff; Paschon, David; Guschin, Dmitry; Rebar, Edward J.; Reik, Andreas; Holmes, Michael C.; Gregory, Philip D.; Restifo, Nicholas P.; Rosenberg, Steven A.; Morgan, Richard A.; Feldman, Steven A. 分享 收藏
Targeted Correction and Restored Function of CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells Davis, Brian R.; Crane, Ana M.; Kramer, Philipp; Bui, Jacquelin H.; Chung, Wook Joon; Li, Xuan Shirley; Gonzalez-Garay, Manuel L.; Hawkins, Finn; Liao, Wei; Mora, Daniela; Wang, Jianbin; Sun, Helena C.; Paschon, David E.; Guschin, Dmitry Y.; Gregory, Philip D.; Kotton, Darrell N.; Holmes, Michael C.; Sorscher, Eric J. 分享 收藏
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Targeted Correction and Restored Function of the CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells 囊性纤维化诱导多能干细胞中CFTR基因的靶向修正和功能恢复 Crane, Ana M.; Kramer, Philipp; Bui, Jacquelin H.; Chung, Wook Joon; Li, Xuan Shirley; Gonzalez-Garay, Manuel L.; Hawkins, Finn; Liao, Wei; Mora, Daniela; Choi, Sangbum; Wang, Jianbin; Sun, Helena C.; Paschon, David E.; Guschin, Dmitry Y.; Gregory, Philip D.; Kotton, Darrell N.; Holmes, Michael C.; Sorscher, Eric J.; Davis, Brian R. 分享 收藏
Improved specificity of TALE-based genome editing using an expanded RVD repertoire 使用扩展的RVD库提高了基于TALE的基因组编辑的特异性 Miller, Jeffrey C.; Zhang, Lei; Xia, Danny F.; Campo, John J.; Ankoudinova, Irina V.; Guschin, Dmitry Y.; Babiarz, Joshua E.; Meng, Xiangdong; Hinkley, Sarah J.; Lam, Stephen C.; Paschon, David E.; Vincent, Anna I.; Dulay, Gladys P.; Barlow, Kyle A.; Shivak, David A.; Leung, Elo; Kim, Jinwon D.; Amora, Rainier; Urnov, Fyodor D.; Gregory, Philip D.; Rebarsimplicity, Edward J. 分享 收藏
A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart (vol 20, pg 1508, 2012) Zhang, H. Steve; Liu, Dingang; Huang, Yan; Schmidt, Stefan; Hickey, Reed; Guschin, Dmitry; Su, Haili; Jovin, Ion S.; Kunis, Mike; Hinkley, Sarah; Liang, Yuxin; Hinh, Linda; Spratt, S. Kaye; Case, Casey C.; Rebar, Edward J.; Ehrlich, Barbara; Gregory, Philip D.; Giordano, Frank J. 分享 收藏
A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart Zhang, H. Steve; Liu, Dingang; Huang, Yan; Schmidt, Stefan; Hickey, Reed; Guschin, Dmitry; Su, Haili; Jovin, Ion S.; Kunis, Mike; Hinkley, Sarah; Liang, Yuxin; Hinh, Linda; Spratt, S. Kaye; Case, Casey C.; Rebar, Edward J.; Ehrlich, Barbara; Gregory, Philip D.; Giordano, Frank J. 分享 收藏
Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases 使用工程化的锌指核酸酶在青蛙非洲爪蟾的体细胞和生殖系中进行有效的靶向基因破坏 Young, John J.; Cherone, Jennifer M.; Doyon, Yannick; Ankoudinova, Irina; Faraji, Farhoud M.; Lee, Andrew H.; Ngo, Catherine; Guschin, Dmitry Y.; Paschon, David E.; Miller, Jeffrey C.; Zhang, Lei; Rebar, Edward J.; Gregory, Philip D.; Urnov, Fyodor D.; Harland, Richard M.; Zeitler, Bryan 分享 收藏
Generation of a Triple-Gene Knockout Mammalian Cell Line Using Engineered Zinc-Finger Nucleases 使用工程化锌指核酸酶产生三基因敲除哺乳动物细胞系 Liu, Pei-Qi; Chan, Edmond M.; Cost, Gregory J.; Zhang, Lin; Wang, Jianbin; Miller, Jeffrey C.; Guschin, Dmitry Y.; Reik, Andreas; Holmes, Michael C.; Mott, John E.; Collingwood, Trevor N.; Gregory, Philip D. 分享 收藏
Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease Johnston, Louisa C.; Su, Xiaomin; Maguire-Zeiss, Kathleen; Horovitz, Karen; Ankoudinova, Irina; Guschin, Dmitry; Hadaczek, Piotr; Federoff, Howard J.; Bankiewicz, Krystof; Forsayeth, John 分享 收藏
Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases Perez, Elena E.; Wang, Jianbin; Miller, Jeffrey C.; Jouvenot, Yann; Kim, Kenneth A.; Liu, Olga; Wang, Nathaniel; Lee, Gary; Bartsevich, Victor V.; Lee, Ya-Li; Guschin, Dmitry Y.; Rupniewski, Igor; Waite, Adam J.; Carpenito, Carmine; Carroll, Richard G.; Orange, Jordan S.; Urnov, Fyodor D.; Rebar, Edward J.; Ando, Dale; Gregory, Philip D.; Riley, James L.; Holmes, Michael C.; June, Carl H. 分享 收藏
Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases 使用工程化锌指核酸酶在哺乳动物细胞中进行靶向基因敲除 Santiago, Yolanda; Chan, Edmond; Liu, Pei-Qi; Orlando, Salvatore; Zhang, Lin; Urnov, Fyoclor D.; Holmes, Michael C.; Guschin, Dmitry; Waite, Adam; Miller, Jeffrey C.; Rebar, Edward J.; Gregory, Philip D.; Klug, Aaron; Collingwood, Trevor N. 分享 收藏
Gene transfer of an engineered zinc finger protein enhances the anti-angiogenic Defense system Yokoi, Katsutoshi; Zhang, Huanda Steve; Kachi, Shu; Balaggan, Kamaljit S.; Yu, Qi; Guschin, Dmitry; Kunis, Mike; Surosky, Richard; Africa, Liza M.; Bainbridge, James W.; Spratt, Sharon Kaye; Gregory, Philip D.; Ali, Robin R.; Campochiaro, Peter A. 分享 收藏
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