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Bernhard Kuhle

University of Gottingen

H指数:14

被引数:770

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Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2

eIF2β与eIF5、eIF2B和5MP1相互作用的分子基础及其受CK2的调控

IF5

2025-10-010

PRE

Dominant-negative NARS1 R534* mutation causes wild-type subunit poisoning and heterodimer predominance in cells

显性负性NARS1 R534*突变导致野生型亚基中毒和异源二聚体在细胞中占主导地位

Journal of Biological Chemistry

IF3.9

2025-09-040

OAAI

Molecular basis of human nuclear and mitochondrial tRNA 3′ processing

人类核基因和线粒体tRNA 3′端加工的分子基础

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2025-01-020

OA

tRNA renovatio: Rebirth through fragmentation

IF16.6

2023-11-0121

OAAI

Clinical and molecular characterization of novel FARS2 variants causing neonatal mitochondrial disease

MOLECULAR GENETICS AND METABOLISM

IF3.5

2023-11-015

OAAI

Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase

NUCLEIC ACIDS RESEARCH

IF13.1

2023-08-281

OAAI

Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition

NATURE COMMUNICATIONS

IF15.7

2023-08-091

OAAI

Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA

NATURE COMMUNICATIONS

IF15.7

2022-08-3013

OAAI

Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability

神经纤毛蛋白1及其抑制配体小色氨酰-tRNA合成酶反向调节VE-钙粘蛋白转换和血管通透性

NATURE COMMUNICATIONS

IF15.7

2022-07-2017

OAAI

PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications (vol 23, pg 424, 2021)

NATURE CELL BIOLOGY

IF19.1

2021-04-293

OAAI

Shi, Junchao; Zhang, Yunfang; Tan, Dongmei; Zhang, Xudong; Yan, Menghong; Zhang, Ying; Franklin, Reuben; Shahbazi, Marta; Mackinlay, Kirsty; Liu, Shichao; Kuhle, Bernhard; James, Emma R.; Zhang, Liwen; Qu, Yongcun; Zhai, Qiwei; Zhao, Wenxin; Zhao, Linlin; Zhou, Changcheng; Gu, Weifeng; Murn, Jernej; Guo, Jingtao; Carrell, Douglas T.; Wang, Yinsheng; Chen, Xuemei; Cairns, Bradley R.; Yang, Xiang-lei; Schimmel, Paul; Zernicka-Goetz, Magdalena; Cheloufi, Sihem; Zhang, Ying; Zhou, Tong; Chen, Qi

PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications

NATURE CELL BIOLOGY

IF19.1

2021-04-05148

OAAI

Shi, Junchao; Zhang, Yunfang; Tan, Dongmei; Zhang, Xudong; Yan, Menghong; Zhang, Ying; Franklin, Reuben; Shahbazi, Marta; Mackinlay, Kirsty; Liu, Shichao; Kuhle, Bernhard; James, Emma R.; Zhang, Liwen; Qu, Yongcun; Zhai, Qiwei; Zhao, Wenxin; Zhao, Linlin; Zhou, Changcheng; Gu, Weifeng; Murn, Jernej; Guo, Jingtao; Carrell, Douglas T.; Wang, Yinsheng; Chen, Xuemei; Cairns, Bradley R.; Yang, Xiang-lei; Schimmel, Paul; Zernicka-Goetz, Magdalena; Cheloufi, Sihem; Zhang, Ying; Zhou, Tong; Chen, Qi

CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-2217

OA

Cross-editing by a tRNA synthetase allows vertebrates to abundantly express mischargeable tRNA without causing mistranslation

NUCLEIC ACIDS RESEARCH

IF13.1

2020-06-0211

OAAI

Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs

NATURE COMMUNICATIONS

IF15.7

2020-02-2017

OAAI

CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-09-0932

OAAI

Distinct ways of G:U recognition by conserved tRNA binding motifs

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-07-0224

OAAI

Architecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2

NUCLEIC ACIDS RESEARCH

IF13.1

2015-09-1737

OAAI

A monovalent cation acts as structural and catalytic cofactor in translational GTPases

IF8.3

2014-09-1525

OAAI

eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining

eIF5B采用一种新的结构域释放机制来催化核糖体亚基的连接

IF8.3

2014-04-0154

OAAI