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A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection Jabalera, Ylenia; Tascon, Igor; Samperio, Sara; Lopez-Alonso, Jorge P.; Gonzalez-Lopez, Monika; Aransay, Ana M.; Abascal-Palacios, Guillermo; Beisel, Chase L.; Ubarretxena-Belandia, Iban; Perez-Jimenez, Raul 分享 收藏
Structural basis for regulation of a CBASS-CRISPR-Cas defense island by a transmembrane anti-σ factor and its ECF σ partner Bernal-Bernal, Diego; Pantoja-Uceda, David; Lopez-Alonso, Jorge Pedro; Lopez-Rojo, Alfonso; Lopez-Ruiz, Jose Antonio; Galbis-Martinez, Marisa; Ochoa-Lizarralde, Borja; Tascon, Igor; Elias-Arnanz, Montserrat; Ubarretxena-Belandia, Iban; Padmanabhan, S. 分享 收藏
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Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane Gonzalez-Magana, Amaia; Tascon, Igor; Altuna-Alvarez, Jon; Queralt-Martin, Maria; Colautti, Jake; Velazquez, Carmen; Zabala, Maialen; Rojas-Palomino, Jessica; Cardenas, Marite; Alcaraz, Antonio; Whitney, John C.; Ubarretxena-Belandia, Iban; Albesa-Jove, David 分享 收藏
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Presenilin1 familial Alzheimer disease mutants inactivate EFNB1-and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-D-aspartate receptor Al Rahim, Md; Yoon, Yonejung; Dimovasili, Christina; Shao, Zhiping; Huang, Qian; Zhang, Emily; Kezunovic, Nebojsa; Chen, Lei; Schaffner, Adam; Huntley, George W.; Ubarretxena-Belandia, Iban; Georgakopoulos, Anastasios; Robakis, Nikolaos K. 分享 收藏
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Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin Gomez-Llorente, Yacob; Jebara, Fady; Patra, Malay; Malik, Radhika; Nisemblat, Shahar; Chomsky-Hecht, Orna; Parnas, Avital; Azem, Abdussalam; Hirsch, Joel A.; Ubarretxena-Belandia, Iban 分享 收藏
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Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection Schaffner, Adam; Li, Xianting; Gomez-Llorente, Yacob; Leandrou, Emmanouela; Memou, Anna; Clemente, Nicolina; Yao, Chen; Afsari, Farinaz; Zhi, Lianteng; Pan, Nina; Morohashi, Keita; Hua, Xiaoluan; Zhou, Ming-Ming; Wang, Chunyu; Zhang, Hui; Chen, Shu G.; Elliott, Christopher J.; Rideout, Hardy; Ubarretxena-Belandia, Iban; Yue, Zhenyu 分享 收藏
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Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis Brown, Mia C.; Abdine, Alaa; Chavez, Jose; Schaffner, Adam; Torres-Arancivia, Celia; Lada, Brian; Jiji, Renee D.; Osman, Roman; Cooley, Jason W.; Ubarretxena-Belandia, Iban 分享 收藏
Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease Hui, Ken Y.; Fernandez-Hernandez, Heriberto; Hu, Jianzhong; Schaffner, Adam; Pankratz, Nathan; Hsu, Nai-Yun; Chuang, Ling-Shiang; Carmi, Shai; Villaverde, Nicole; Li, Xianting; Rivas, Manual; Levine, Adam P.; Bao, Xiuliang; Labrias, Philippe R.; Haritunians, Talin; Ruane, Darren; Gettler, Kyle; Chen, Ernie; Li, Dalin; Schiff, Elena R.; Pontikos, Nikolas; Barzilai, Nir; Brant, Steven R.; Bressman, Susan; Cheifetz, Adam S.; Clark, Lorraine N.; Daly, Mark J.; Desnick, Robert J.; Duerr, Richard H.; Katz, Seymour; Lencz, Todd; Myers, Richard H.; Ostrer, Harry; Ozelius, Laurie; Payami, Haydeh; Peter, Yakov; Rioux, John D.; Segal, Anthony W.; Scott, William K.; Silverberg, Mark S.; Vance, Jeffery M.; Ubarretxena-Belandia, Iban; Foroud, Tatiana; Atzmon, Gil; Pe'er, Itsik; Ioannou, Yiannis; McGovern, Dermot P. B.; Yue, Zhenyu; Schadt, Eric E.; Cho, Judy H.; Peter, Inga 分享 收藏