Jin Liu - Publications, H-index & Citations

Jin Liu

University of North Texas Health Science Center

34H指数

121论文数

3.8K被引数

收录论文 63

发表时间

Structure-Based Classification of CRISPR/Cas9 Proteins: A Machine Learning Approach to Elucidating Cas9 Allostery 基于结构的CRISPR/Cas9蛋白分类：一种阐明Cas9变构效应的机器学习方法

Journal of Molecular Biology

IF4.5

2025-11-09

PREAI

Sita Sirisha Madugula; Vindi M. Jayasinghe-Arachchige; Charlene R. Norgan Radler; Shouyi Wang; Jin Liu

I-GAT: Interpretable Graph Attention Networks for Ligand Optimization I-GAT：用于配体优化的可解释图注意力网络

ACS Omega

IF4.3

2025-07-21

OAAI

Ezek Mathew; Kyle A. Emmitte; Jin Liu

CircITSN1/EIF4A3/Itsn1 axis mediates postoperative cognitive dysfunction in aged mice: A novel mechanism and therapeutic target CircITSN1/EIF4A3/Itsn1轴调控老年小鼠术后认知功能障碍：一种新的机制和治疗靶点

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2025-06-01

OAAI

Changteng Zhang; Xiaoyu Zhu; Rui Gao; Hai Chen; Caiyi Yan; Wangyang Liu; Lina Yang; Xianzheng Zeng; Haoran Yang; Jin Liu; Qi Li; Daqing Ma; Tao Zhu; Chan Chen

Lingo1 in the hippocampus contributes to cognitive dysfunction after anesthesia and surgery in aged mice 海马体中的Lingo1在麻醉和手术后的认知功能障碍中起作用，该现象出现在老年小鼠中。

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES

IF10

2025-01-01

OAAI

Liu, Changliang; Zhang, Changteng; Chen, Ling; Liu, Xin; Wu, Jiahui; Sun, Yalan; Liu, Jin; Chen, Chan

Identification of Family-Specific Features in Cas9 and Cas12 Proteins: A Machine Learning Approach Using Complete Protein Feature Spectrum

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2024-06-05

OAAI

Madugula, Sita Sirisha; Pujar, Pranav; Nammi, Bharani; Wang, Shouyi; Jayasinghe-Arachchige, Vindi M.; Pham, Tyler; Mashburn, Dominic; Artiles, Maria; Liu, Jin

Anemoside B4 attenuates necrotic enteritis of laying hens induced by Clostridium perfringens via inhibiting NF-κB κ B and PI3K/Akt/ mTOR signalling pathways Anemoside B4通过抑制nf-κb κ B和PI3K/Akt/ mTOR信号通路减轻产气荚膜梭菌诱导的蛋鸡坏死性肠炎

HELIYON

IF3.6

2024-06-01

OAAI

Tian, Xinyue; Li, Jingyang; Liu, Siyu; Dong, Qiaoli; Fu, Yunjian; Luo, Ronghui; Sun, Yamin; Guo, Ling; Lu, Qirong; Ye, Chun; Liu, Jin; Fu, Shulin; Qiu, Yinsheng

Secondary Conformational Checkpoint in CRISPR-Cas9

JOURNAL OF CHEMICAL THEORY AND COMPUTATION

IF5.5

2024-04-16

PREAI

Zhao, Shuxin; Liu, Jin; Zuo, Zhicheng

Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage

CRISPR JOURNAL

IF4

2023-12-01

OAAI

Newsom, Sydney N.; Wang, Duen-Shian; Rostami, Saadi; Schuster, Isabelle; Parameshwaran, Hari Priya; Joseph, Yadin G.; Qin, Peter Z.; Liu, Jin; Rajan, Rakhi

Cynapanoside A exerts protective effects against obesity-induced diabetic nephropathy through ameliorating TRIM31-mediated inflammation, lipid synthesis and fibrosis (vol 113, 109395, 2022)

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2023-12-01

PREAI

Luo, Jing; Tan, Jun; Zhao, Junjie; Wang, Longyan; Liu, Jin; Dai, Xianling; Sun, Yan; Kuang, Qin; Hui, Junmin; Chen, Jinfeng; Kuang, Gang; Chen, Shaocheng; Wang, Yangli; Ge, Chenxu; Xu, Minxuan

Leveraging QM/MM and Molecular Dynamics Simulations to Decipher the Reaction Mechanism of the Cas9 HNH Domain to Investigate Off-Target Effects

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2023-10-25

PREAI

Maghsoud, Yazdan; Jayasinghe-Arachchige, Vindi M.; Kumari, Pratibha; Cisneros, G. Andres; Liu, Jin

Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants

NUCLEIC ACIDS RESEARCH

IF13.1

2023-03-17

OAAI

Wang, Qian; Liu, Jin; Janssen, Josephine M.; Goncalves, Manuel A. F., V

High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2023-03-01

OAAI

Tasca, Francesca; Brescia, Marcella; Liu, Jin; Janssen, Josephine M.; Mamchaoui, Kamel; Goncalves, Manuel A. F. V.

Programmable Assembly of Amphiphilic DNA through Controlled Cholesterol Stacking

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-08-30

PREAI

Liu, Jin; Chen, Liman; Zhai, Tingting; Li, Wei; Liu, Yuehua; Gu, Hongzhou

Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells

NUCLEIC ACIDS RESEARCH

IF13.1

2022-07-01

OAAI

Tasca, Francesca; Brescia, Marcella; Wang, Qian; Liu, Jin; Janssen, Josephine M.; Szuhai, Karoly; Goncalves, Manuel A. F., V

Sparse group selection and analysis of function-related residue for protein-state recognition

JOURNAL OF COMPUTATIONAL CHEMISTRY

IF4.8

2022-06-03

OAAI

Bai, Fangyun; Puk, Kin Ming; Liu, Jin; Zhou, Hongyu; Tao, Peng; Zhou, Wenyong; Wang, Shouyi

Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects

CRISPR JOURNAL

IF4

2022-04-01

OAAI

Zuo, Zhicheng; Babu, Kesavan; Ganguly, Chhandosee; Zolekar, Ashwini; Newsom, Sydney; Rajan, Rakhi; Wang, Yu-Chieh; Liu, Jin

Design of SARS-CoV-2 Mpro, PLpro dual-target inhibitors based on deep reinforcement learning and virtual screening 基于深度强化学习和虚拟筛选的SARS-CoV-2 Mpro、PLpro双靶点抑制剂设计

FUTURE MEDICINAL CHEMISTRY

IF3.4

2022-02-27

OAAI

Zhang, Li-chuan; Zhao, Hui-lin; Liu, Jin; He, Lei; Yu, Ri-lei; Kang, Cong-min

Optimization of metabolomic data processing using NOREVA 使用NOREVA优化代谢组学数据处理

NATURE PROTOCOLS

IF16

2021-12-24

139

PREAI

Fu, Jianbo; Zhang, Ying; Wang, Yunxia; Zhang, Hongning; Liu, Jin; Tang, Jing; Yang, Qingxia; Sun, Huaicheng; Qiu, Wenqi; Ma, Yinghui; Li, Zhaorong; Zheng, Mingyue; Zhu, Feng

Development of MDM2 degraders based on ligands derived from Ugi reactions: Lessons and discoveries 基于Ugi反应衍生的配体的MDM2降解剂的开发: 教训和发现

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-07-01

OAAI

Wang, Bo; Liu, Jin; Tandon, Ira; Wu, Suzhen; Teng, Peng; Liao, Jianhua; Tang, Weiping

Unmet Communication Needs and Barriers of Black and African Americans with Type 2 Diabetes

DIABETES

IF7.5

2021-06-01

PREAI

Zisman-Ilani, Yaara; Siminoff, Laura A.; Savoy, Margot L.; Paranjape, Anuradha; Liu, Jin; Jacob, Regina A.; Gardiner, Heather M.; Bass, Sarah B.; Montori, Victor M.; Rubin, Daniel J.

研究方向