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收藏分享 收藏 Dihydroartemisinin requires NR1D1 mediated Rab7 ubiquitination to regulate hepatic stellate cells lipophagy in liver fibrosis双氢青蒿素需要NR1D1介导的Rab7泛素化来调控肝纤维化中肝星状细胞的脂质自噬。
Bao, Zhengyang; Xu, Min; Kan, Yifan; Guo, Xiaohan; Li, Mengran; Wang, Junrui; Zhou, Ya; Zhang, Zili; Shao, Jiangjuan; Zhang, Feng; Chen, Li; Zheng, Shizhong 分享 收藏 Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects大蒜中的二烯丙基三硫化物通过调控RAB18相分离来抑制脂噬并诱导铜死亡，从而在肝星状细胞中发挥抗纤维化作用。Tian, HY; Sun, SJ; Qiu, XR; Wang, JR; Gao, YY; Chen, JM; Han, X; Bao, ZY; Guo, XH; Sun, YQ; Lin, YX; Hu, MR; Zhang, F; Zhang, ZL; Wang, FX; Zheng, SZ; Shao, JJ 分享 收藏 分享 收藏 NUMB endocytic adaptor protein (NUMB) mediates the anti-hepatic fibrosis effect of artesunate (ART) by inducing senescence in hepatic stellate cells (HSCs)NUMB内吞衔接蛋白 (NUMB) 通过诱导肝星状细胞 (hsc) 衰老介导青蒿琥酯 (ART) 的抗肝纤维化作用Qiu, Yangling; Li, Yujia; Li, Mengran; Wang, Yingqian; Shen, Min; Shao, Jiangjuan; Zhang, Feng; Xu, Xuefen; Wang, Feixia; Zhang, Zili; Zheng, Shizhong 分享 收藏 Oxidative stress induces ferroptosis in tendon stem cells by regulating mitophagy through cGAS-STING pathwayGao, Yuanyuan; Sun, Wenshuang; Wang, Junrui; Zhao, Danli; Tian, Haoyuan; Qiu, Yangling; Ji, Shufan; Wang, Shuqi; Fu, Qiuyu; Zhang, Feng; Zhang, Zili; Wang, Feixia; Shao, Jiangjuan; Zheng, Shizhong; Meng, Jia 分享 收藏 分享 收藏 Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional complexWang, Feixia; Chen, Li; Kong, Desong; Zhang, Xiaojin; Xia, Siwei; Liang, Baoyu; Li, Yang; Zhou, Ya; Zhang, Zili; Shao, Jiangjuan; Zheng, Shizhong; Zhang, Feng 分享 收藏 Artesunate Induces Ferroptosis in Hepatic Stellate Cells and Alleviates Liver Fibrosis via the ROCK1/ATF3 AxisWang, Yingqian; Li, Yujia; Qiu, Yangling; Shen, Min; Wang, Ling; Shao, Jiangjuan; Zhang, Feng; Xu, Xuefen; Zhang, Zili; Guo, Mei; Zheng, Shizhong 分享 收藏 Emodin promotes hepatic stellate cell senescence and alleviates liver fibrosis via a nuclear receptor (Nur77)-mediated epigenetic regulation of glutaminase 1大黄素通过核受体 (Nur77) 介导的谷氨酰胺酶1的表观遗传调控促进肝星状细胞衰老和减轻肝纤维化Chen, Li; Liang, Baoyu; Xia, Siwei; Wang, Feixia; Li, Zhanghao; Shao, Jiangjuan; Zhang, Zili; Chen, Anping; Zheng, Shizhong; Zhang, Feng 分享 收藏 Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathwayOroxylin A通过调节cgas-sting通路激活ferritinophagy诱导肝星状细胞衰老对抗肝纤维化Sun, Ying; Weng, Jingdan; Chen, Xiaolei; Ma, Shuyao; Zhang, Yuxin; Zhang, Feng; Zhang, Zili; Wang, Feixia; Shao, Jiangjuan; Zheng, Shizhong 分享 收藏 Blockade of KLF5/LDH-A feedback loop contributes to Curcumol inhibition of sinusoidal endothelial cell glycolysis and mitigation of liver fibrosisLi, Yang; Zhou, Yuanyuan; Xia, Siwei; Chen, Li; Yang, Ting; Zhao, Danli; Zhang, Zili; Shao, Jiangjuan; Xu, Xuefen; Zhang, Feng; Zheng, Shizhong 分享 收藏 m6A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosisChen, Li; Xia, Siwei; Wang, Feixia; Zhou, Yuanyuan; Wang, Shuqi; Yang, Ting; Li, Yang; Xu, Min; Zhou, Ya; Kong, Desong; Zhang, Zili; Shao, Jiangjuan; Xu, Xuefen; Zhang, Feng; Zheng, Shizhong 分享 收藏 Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescenceZhao, Danli; Gao, Yuanyuan; Su, Ying; Zhou, Yuanyuan; Yang, Ting; Li, Yang; Wang, Yingqian; Sun, Ying; Chen, Li; Zhang, Feng; Zhang, Zili; Wang, Feixia; Shao, Jiangjuan; Zheng, Shizhong 分享 收藏 Qingchang Wenzhong Decoction reduce ulcerative colitis in mice by inhibiting Th17 lymphocyte differentiationXia, Siwei; Chen, Li; Li, Zhanghao; Li, Yang; Zhou, Yuanyuan; Sun, Sumin; Su, Ying; Xu, Xuefen; Shao, Jiangjuan; Zhang, Zili; Kong, Desong; Zhang, Feng; Zheng, Shizhong 分享 收藏 Inhibition of ASCT2 induces hepatic stellate cell senescence with modified proinflammatory secretome through an IL-1α/NF-κB feedback pathway to inhibit liver fibrosisWang, Feixia; Li, Zhanghao; Chen, Li; Yang, Ting; Liang, Baoyu; Zhang, Zili; Shao, Jiangjuan; Xu, Xuefen; Yin, Guoping; Wang, Shijun; Ding, Hai; Zhang, Feng; Zheng, Shizhong 分享 收藏 Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cellsSun, Sumin; Li, Zhanghao; Huan, Sheng; Kai, Jun; Xia, Siwei; Su, Ying; Ji, Shufan; Chen, Anping; Wang, Shijun; Xu, Xuefen; Shao, Jiangjuan; Zhang, Feng; Zhang, Biyun; Zhang, Zili; Zheng, Shizhong 分享 收藏 Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING PathwayChen, Li; Xia, Siwei; Wang, Shuqi; Zhou, Yuanyuan; Wang, Feixia; Li, Zhanghao; Li, Yang; Kong, Desong; Zhang, Zili; Shao, Jiangjuan; Xu, Xuefen; Zhang, Feng; Zheng, Shizhong 分享 收藏 O-GlcNAcylation Coordinates Glutaminolysis by Regulating the Stability and Membrane Trafficking of ASCT2 in Hepatic Stellate CellsWang, Feixia; Chen, Li; Zhang, Biyun; Li, Zhanghao; Shen, Min; Tang, Li; Zhang, Zili; Shao, Jiangjuan; Zhang, Feng; Zheng, Shizhong; Tan, Shanzhong 分享 收藏 
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