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Atsuro Saijo

University of California System
H指数:13
被引数:663

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Focused ultrasound-mediated blood-brain barrier disruption, combined with antigen-presenting cell activation, promotes CNS antigen-specific T cell immunity and bypasses immunotherapy resistance mechanism in malignant brain tumors

聚焦超声介导的血脑屏障破坏,结合抗原提呈细胞激活,促进中枢神经系统抗原特异性T细胞免疫,并绕过恶性脑肿瘤的免疫疗法耐药机制。

2025-11-010
OAAI
TUMOR-WIDE RNA SPLICING ABERRATIONS GENERATE IMMUNOGENIC PUBLIC NEOANTIGENS IN GLIOBLASTOMAS AND OTHER CANCER TYPES
2024-11-110
PRE
LOW-INTENSITY PULSED ULTRASOUND COMBINED WITH POLY-ICLC AND INTERLEUKIN-2 UNLOCKS THE IMMUNE PRIVILEGE OF THE BRAIN BY PROMOTING EPITOPE SPREADING AND ACTIVATION OF CNS-SPECIFIC NAÏVE T CELLS

低强度脉冲超声联合poly-iclc和INTERLEUKIN-2通过促进CNS特异性初始T细胞的表位扩散和激活来解锁大脑的免疫特权

2024-11-110
PRE
T-CELL THERAPY COMBINED WITH LOW-INTENSITY PULSED FOCUSED ULTRASOUND, MICROBUBBLES AND POLY-ICLC PROMOTES THE PRESENTATION OF BRAIN-DERIVED ANTIGENS, BREAKING CNS TOLERANCE AND INDUCING ACTIVE T-CELL RESPONSES
2024-10-170
PRE
Novel public and tumor-wide neoantigens arising from clonal aberrant splicing events drive tumor-specific T-cell responses across diverse cancer types
2024-03-220
PRE
Low-intensity pulsed ultrasound enhances the presentation of brain-derived antigens by facilitating the migration of antigen-presenting cells from the brain to the periphery
2024-03-220
PRE
A combinatory vaccine with IMA950 plus varlilumab promotes effector memory T-cell differentiation in the peripheral blood of patients with low-grade gliomas
2023-09-276
PRE
Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas
2022-02-0141
PRE
Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells
2018-04-3014
OAAI
Thymidine Catabolism as a Metabolic Strategy for Cancer Survival
2017-05-0147
OAAI