Zhongjun Ma

Zhejiang University

H指数:29

被引数:2,712

个人简介

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Design; Synthesis; and Evaluation of a Potent and Selective ROCK2 Inhibitor for Atopic Dermatitis Treatment

Journal of Medicinal Chemistry

IF6.8

2026-01-230

PRE

DGMM: A Deep Learning-Genetic Algorithm Framework for Efficient Lead Optimization in Drug Discovery

DGMM：一种用于药物发现中高效先导化合物优化的深度学习-遗传算法框架

Journal of Chemical Information and Modeling

IF5.3

2025-07-300

PRE

A modular artificial intelligence framework to facilitate fluorophore design

一种模块化人工智能框架，用于促进荧光团设计

NATURE COMMUNICATIONS

IF15.7

2025-04-160

Discovery of New Difluorocyclobutyl Derivatives as Effective Glucagon-Like Peptide-1 Receptor Agonists with Reduced hERG Inhibitory Activities

发现新的二氟环丁基衍生物作为高效胰高血糖素样肽-1受体激动剂，且具有降低的hERG抑制活性

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-04-010

PRE

Transgenerational toxicity assessment of [C8mim]Br: Focus on early development, antioxidant defense, and transcriptome profiles in zebrafish

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

IF6.1

2025-02-010

OAAI

Discovery of the First-in-Class Dual-Target ROCK/HDAC Inhibitor with Potent Antitumor Efficacy in Vivo That Trigger Antitumor Immunity

发现首例双靶点ROCK/HDAC抑制剂，在体内具有强大的抗肿瘤功效，可触发抗肿瘤免疫

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-11-111

PRE

Respiratory adverse effects in patients treated with immune checkpoint inhibitors in combination with radiotherapy: a systematic review and meta-analysis

RADIATION ONCOLOGY

IF3.2

2024-10-011

OAAI

Natural Derivatives of Selective HDAC8 Inhibitors with Potent in Vivo Antitumor Efficacy against Breast Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-08-071

PRE

Bipyridine Derivatives as NOP2/Sun RNA Methyltransferase 3 Inhibitors for the Treatment of Colorectal Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-07-262

PRE

Association of pathological response with long-term survival outcomes after neoadjuvant immunotherapy: A meta-analysis

新辅助免疫治疗后病理反应与长期生存结局关系的meta分析

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2024-05-010

PRE

Design, Synthesis, and Biological Evaluation of an Orally Bioavailable, Potent, and Selective ROCK2 Inhibitor for Psoriasis Treatment

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-11-094

PRE

Photo-aging promotes the inhibitory effect of polystyrene microplastics on microbial reductive dechlorination of a polychlorinated biphenyl mixture (Aroclor 1260)

JOURNAL OF HAZARDOUS MATERIALS

IF11.3

2023-06-015

PRE

Discovery of unglycosylated indolocarbazoles as ROCK2 isoform-selective inhibitors for the treatment of breast cancer metastasis

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-03-015

PRE

Suncheonosides E-M and Benzothioate Derivatives from the Marine-Derived Streptomyces sp. ZSN77

JOURNAL OF NATURAL PRODUCTS

IF3.6

2022-06-2810

PRE

Tumor progress intercept by intervening in Caveolin-1 related intercellular communication via ROS-sensitive c-Myc targeting therapy

BIOMATERIALS

IF12.9

2021-08-0111

PREAI

Design, Synthesis and Structure-Activity Relationship Studies of Glycosylated Derivatives of Marine Natural Product Lamellarin D

海洋天然产物Lamellarin D糖基化衍生物的设计、合成及构效关系研究

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-03-0132

PREAI

Role of long non-coding RNA H19 in therapy resistance of digestive system cancers

长链非编码RNA H19在消化系统肿瘤耐药中的作用

MOLECULAR MEDICINE

IF6.4

2021-01-0523

OAAI

Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway

TOXICOLOGY AND APPLIED PHARMACOLOGY

IF3.4

2020-12-011

OAAI

Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-10-2650

OAAI

Identification, Structure-Activity Relationships of Marine-Derived Indolocarbazoles, and a Dual PKCθ/δ Inhibitor with Potent Antipancreatic Cancer Efficacy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-10-2516

PREAI

Zhongjun Ma

个人简介

教育背景

工作经历

荣誉奖项

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