未登录 A Facile Protocol for C(sp2)-C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands 面向功能化E3连接酶配体的C(sp2)-C(sp3) 键形成反应的简便方案 Maksutova, Anita; Geiger, Thomas M.; Cianni, Lorenzo; Pienkowska, Dominika E.; Gerhartz, Jan; Read, Lina; Bricelj, Alesa; Herrmann, Alexander; Nelles, Maurice Leon; Ng, Yuen Lam Dora; Hartmann, Marcus D.; Kronke, Jan; Sosic, Izidor; Nowak, Radoslaw P.; Gutschow, Michael; Steinebach, Christian 分享 收藏
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Contribution of direct InhA inhibitors to novel drug regimens in a mouse model of tuberculosis Encinas, Lourdes; Li, Si-Yang; Rullas-Trincado, Joaquin; Tasneen, Rokeya; Tyagi, Sandeep; Soni, Heena; Garcia-Perez, Adolfo; Lee, Jin; del Rio, Ruben Gonzalez; De Mercado, Jaime; Sousa, Veronica; Sosic, Izidor; Gobec, Stanislav; Mendoza-Losana, Alfonso; Converse, Paul J.; Mdluli, Khisi; Fotouhi, Nader; Barros-Aguirre, David; Nuermberger, Eric L. 分享 收藏
Design, Synthesis, and Evaluation of BCL-2 Targeting PROTACs BCL-2靶向PROTACs的设计、合成与评价 Bricelj, Alesa; Ng, Yuen Lam Dora; Gobec, Martina; Kuchta, Robert; Hu, Wanyi; Javornik, Spela; Rozic, Miha; Guetschow, Michael; Zheng, Guangrong; Kroenke, Jan; Steinebach, Christian; Sosic, Izidor 分享 收藏
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Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs Steinebach, Christian; Bricelj, Alesa; Murgai, Arunima; Sosic, Izidor; Bischof, Luca; Ng, Yuen Lam Dora; Heim, Christopher; Maiwald, Samuel; Proj, Matic; Voget, Rabea; Feller, Felix; Kosmrlj, Janez; Sapozhnikova, Valeriia; Schmidt, Annika; Zuleeg, Maximilian Rudolf; Lemnitzer, Patricia; Mertins, Philipp; Hansen, Finn K.; Guetschow, Michael; Kroenke, Jan; Hartmann, Marcus D. 分享 收藏
Expanding the Structural Diversity at the Phenylene Core of Ligands for the von Hippel-Lindau E3 Ubiquitin Ligase: Development of Highly Potent Hypoxia-Inducible Factor-1α Stabilizers Vu, Lan Phuong; Diehl, Claudia J.; Casement, Ryan; Bond, Adam G.; Steinebach, Christian; Strasek, Nika; Bricelj, Alesa; Perdih, Andrej; Schnakenburg, Gregor; Sosic, Izidor; Ciulli, Alessio; Guetschow, Michael 分享 收藏
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Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins Ng, Yuen Lam Dora; Bricelj, Alesa; Jansen, Jacqueline A.; Murgai, Arunima; Peter, Kirsten; Donovan, Katherine A.; Guetschow, Michael; Kroenke, Jan; Steinebach, Christian; Sosic, Izidor 分享 收藏
Accessing three-branched high-affinity cereblon ligands for molecular glue and protein degrader design Kuchta, Robert; Heim, Christopher; Herrmann, Alexander; Maiwald, Samuel; Ng, Yuen Lam Dora; Sosic, Izidor; Keuler, Tim; Kroenke, Jan; Guetschow, Michael; Hartmann, Marcus D.; Steinebach, Christian 分享 收藏
Repurposing of 8-Hydroxyquinoline-Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors Gajic, Mihajlo; Knez, Damijan; Sosic, Izidor; Mravljak, Janez; Meden, Anze; Kosak, Urban; Leitzbach, Luisa; George, Sven; Hofmann, Bettina; Zivkovic, Aleksandra; Steinhilber, Dieter; Stark, Holger; Gobec, Stanislav; Smelcerovic, Andrija; Anderluh, Marko 分享 收藏
Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti-SARS-CoV-2 Activity Schulte, Bianca; Koenig, Maria; Escher, Beate, I; Wittenburg, Sophie; Proj, Matic; Wolf, Valentina; Lemke, Carina; Schnakenburg, Gregor; Sosic, Izidor; Streeck, Hendrik; Mueller, Christa E.; Guetschow, Michael; Steinebach, Christian 分享 收藏
Nitroxoline and its derivatives are potent inhibitors of metallo-13-lactamases Proschak, Anna; Martinelli, Giada; Frank, Denia; Rotter, Marco J.; Brunst, Steffen; Weizel, Lilia; Burgers, Luisa D.; Fuerst, Robert; Proschak, Ewgenij; Sosic, Izidor; Gobec, Stanislav; Wichelhaus, Thomas A. A. 分享 收藏
Targeting the deubiquitinase USP7 for degradation with PROTACs Murgai, Arunima; Sosic, Izidor; Gobec, Martina; Lemnitzer, Patricia; Proj, Matic; Wittenburg, Sophie; Voget, Rabea; Guetschow, Michael; Kroenke, Jan; Steinebach, Christian 分享 收藏
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