Zacarias Garcia - Publications, H-index & Citations

Zacarias Garcia

université parís cité

31H指数

54论文数

3.5K被引数

收录论文 39

发表时间

Distinct migratory dendritic cell subsets cooperate to prime tissue-resident memory-like CD8⁺ T cells in mouse tumors 不同迁移性树突状细胞亚群协同作用以启动小鼠肿瘤中组织驻留记忆样CD8⁺ T细胞

Nature Communications

IF15.7

2026-09-18

OAAI

Nathan Vaudiau; Pierre Bourdely; Maria Semitekolou; Agathe Ok; Louise Gorline; Aboubacar Sidiki K. Coulibaly; Matthieu Rastello; Aurélie Semervil; Roberto Savoldelli; Yohan Gerber-Ferder; Fillipe Luiz Rosa do Carmo; Mathias Vétillard; Audrey Rood; Jérémie Bornères; Abdenour Abbas; Marie Guillin; Judith Weber; Syrine Bouallegue; Konstantina Pamboukas; Zacarias Garcia; Florent Ginhoux; Camille Blériot; Philippe Bousso; Yosuke Kumamoto; Guillaume Darrasse-Jèze; Emmanuel L. Gautier; Marc Dalod; Eric Tartour; Tessa Bergsbaken; Klaas P. J. M. Van Gisbergen; Kairbaan M. Hodivala-Dilke; Massimiliano Mazzone; Loredana Saveanu; Julie Helft; Federica Benvenuti; Pierre Guermonprez

Lymph node microenvironment remodeling unlocks local antibody-mediated B cell depletion 淋巴结微环境重塑解锁局部抗体介导的B细胞耗竭

Science Advances

IF12.5

2026-06-10

OAAI

Zacarias Garcia; Margot Bardou; Anne Loap; Lea C. Feldmann; Ophélie Godon; Marion V. Guerin; Fabrice Lemaître; Lynn E. Macdonald; Pierre Bruhns; Nicolas Serafini; Philippe Bousso; Capucine L. Grandjean

Reprogramming RIPK3-induced cell death in malignant B cells promotes immune-mediated tumor control 重编程RIPK3诱导的恶性B细胞死亡可促进免疫介导的肿瘤控制

Science Advances

IF12.5

2025-08-15

OAAI

Ruby Alonso; Zacarias Garcia; Béatrice Corre; Fabrice Lemaître; Camille Vaganay; Hélène Saklani; Capucine L. Grandjean; Nader Yatim; Philippe Bousso

Anti-PD-1 therapy triggers Tfh cell-dependent IL-4 release to boost CD8 T cell responses in tumor-draining lymph nodes

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2024-02-28

OAAI

Ruggiu, Mathilde; Guerin, Marion V.; Corre, Beatrice; Bardou, Margot; Alonso, Ruby; Russo, Erica; Garcia, Zacarias; Feldmann, Lea; Lemaitre, Fabrice; Dusseaux, Mathilde; Grandjean, Capucine L.; Bousso, Philippe

Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity 肿瘤对ifn-γ 的促凋亡作用的内在敏感性是CD4 CAR T细胞抗肿瘤活性的主要决定因素

NATURE CANCER

IF28.5

2023-05-29

OAAI

Boulch, Morgane; Cazaux, Marine; Cuffel, Alexis; Guerin, Marion V.; Garcia, Zacarias; Alonso, Ruby; Lemaitre, Fabrice; Beer, Alexander; Corre, Beatrice; Menger, Laurie; Grandjean, Capucine L.; Morin, Florence; Thieblemont, Catherine; Caillat-Zucman, Sophie; Bousso, Philippe

Inflammation triggers ILC3 patrolling of the intestinal barrier

NATURE IMMUNOLOGY

IF27.6

2022-08-23

OAAI

Jarade, Angelique; Garcia, Zacarias; Marie, Solenne; Demera, Abdi; Prinz, Immo; Bousso, Philippe; Di Santo, James P.; Serafini, Nicolas

Spatiotemporal dynamics of calcium signals during neutrophil cluster formation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-12

OAAI

Khazen, Roxana; Corre, Beatrice; Garcia, Zacarias; Lemaitre, Fabrice; Bachellier-Bassi, Sophie; D'Enfert, Christophe; Bousso, Philippe

Quorum sensing governs collective dendritic cell activation in vivo

EMBO JOURNAL

IF8.3

2021-06-14

OAAI

Bardou, Margot; Postat, Jeremy; Loaec, Clemence; Lemaitre, Fabrice; Ronteix, Gustave; Garcia, Zacarias; Bousso, Philippe

Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo

EMBO JOURNAL

IF8.3

2021-04-15

OAAI

Khazen, Roxana; Cazaux, Marine; Lemaitre, Fabrice; Corre, Beatrice; Garcia, Zacarias; Bousso, Philippe

A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity

SCIENCE IMMUNOLOGY

IF16.3

2021-03-04

130

OAAI

Boulch, Morgane; Cazaux, Marine; Loe-Mie, Yann; Thibaut, Ronan; Corre, Beatrice; Lemaitre, Fabrice; Grandjean, Capucine L.; Garcia, Zacarias; Bousso, Philippe

Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis

SCIENCE ADVANCES

IF12.5

2021-02-19

OAAI

Grandjean, Capucine L.; Garcia, Zacarias; Lemaitre, Fabrice; Breart, Beatrice; Bousso, Philippe

Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment 旁观者ifn-γ 活性促进广泛和持续的细胞因子信号传导改变肿瘤微环境

NATURE CANCER

IF28.5

2020-03-09

110

OAAI

Thibaut, Ronan; Bost, Pierre; Milo, Idan; Cazaux, Marine; Lemaitre, Fabrice; Garcia, Zacarias; Amit, Ido; Breart, Beatrice; Cornuot, Clemence; Schwikowski, Benno; Bousso, Philippe

Optogenetic manipulation of calcium signals in single T cells in vivo

NATURE COMMUNICATIONS

IF15.7

2020-03-02

OAAI

Bohineust, Armelle; Garcia, Zacarias; Corre, Beatrice; Lemaitre, Fabrice; Bousso, Philippe

Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2019-04-01

104

OAAI

Cazaux, Marine; Grandjean, Capucine L.; Lemaitre, Fabrice; Garcia, Zacarias; Beck, Richard J.; Milo, Idan; Postat, Jeremy; Beltman, Joost B.; Cheadle, Eleanor J.; Bousso, Philippe

The immune system profoundly restricts intratumor genetic heterogeneity

SCIENCE IMMUNOLOGY

IF16.3

2018-11-30

PREAI

Milo, Idan; Bedora-Faure, Marie; Garcia, Zacarias; Thibaut, Ronan; Perie, Leila; Shakhar, Guy; Deriano, Ludovic; Bousso, Philippe

A human immune system mouse model with robust lymph node development

NATURE METHODS

IF32.1

2018-07-31

PREAI

Li, Yan; Masse-Ranson, Guillemette; Garcia, Zacarias; Bruel, Timothee; Kok, Ayrin; Strick-Marchand, Helene; Jouvion, Gregory; Serafini, Nicolas; Lim, Ai Ing; Dusseaux, Mathilde; Hieu, Thierry; Bourgade, Franck; Toubert, Antoine; Finke, Daniela; Schwartz, Olivier; Bousso, Philippe; Mouquet, Hugo; Di Santo, James P.

Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2018-03-27

OAAI

Bohineust, Armelle; Garcia, Zacarias; Beuneu, Helene; Lemaitre, Fabrice; Bousso, Philippe

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies

SCIENTIFIC REPORTS

IF3.9

2016-10-04

OAAI

Grandjean, Capucine L.; Montalvao, Fabricio; Celli, Susanna; Michonneau, David; Breart, Beatrice; Garcia, Zacarias; Perro, Mario; Freytag, Olivier; Gerdes, Christian A.; Bousso, Philippe

The PD-1 Axis Enforces an Anatomical Segregation of CTL Activity that Creates Tumor Niches after Allogeneic Hematopoietic Stem Cell Transplantation

IMMUNITY

IF26.3

2016-01-01

OAAI

Michonneau, David; Sagoo, Pervinder; Breart, Beatrice; Garcia, Zacarias; Celli, Susanna; Bousso, Philippe

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

NATURE MEDICINE

IF50

2015-12-21

109

OAAI

Sagoo, Pervinder; Garcia, Zacarias; Breart, Beatrice; LemaOtre, Fabrice; Michonneau, David; Albert, Matthew L.; Levy, Yves; Bousso, Philippe

研究方向