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K

Khaled Barakat

university of alberta

36H指数
177论文数
3.9K被引数
收录论文 56
发表时间
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Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation晚期INa作为治疗靶点：新策略、计算建模、药物开发和临床转化
errMedicinal Research Reviews
IF11.6
err2026-07-28
err0
errOAAI
errArkapravo Chattopadhyay; Lynn C. Lunsonga; Peter E. Light; Khaled Barakat
err分享
err收藏
AI-MedCraft: A Strategy-Driven AI Platform for Multi-Objective Molecular DesignAI-MedCraft：一种策略驱动的多目标分子设计人工智能平台
errJournal of Chemical Information and Modeling
IF5.3
err2026-03-01
err0
PREAI
errBarakat, Khaled; Rojas Ruiz, Michael Jordy; Ahmed, Hazem; Shahini, Ehsan; Barakat, Yomna
err分享
err收藏
Multiscale computational analysis reveals enhanced allosteric modulation of Nav1.5 by dual binding of dapagliflozin and ertugliflozin多尺度计算分析揭示了达格列净和ertugliflozin双重结合对Nav1.5的增强别构调控。
errScientific Reports
IF3.9
err2025-12-02
err0
errOAAI
errArkapravo Chattopadhyay; Mohammad Fatehi; Farag E. S. Mosa; Brittany Gruber; Peter E. Light; Khaled Barakat
err分享
err收藏
A chemoproteomic strategy for identifying protein covalent binding targets of clozapine: an approach for advancing clozapine toxicity research一种用于识别氯氮平蛋白共价结合靶点的化学蛋白质组学策略：一种促进氯氮平毒性研究的策略
errToxicology Letters
IF2.9
err2025-10-21
err0
errOAAI
errSteven Lockhart; Yasser Tabana; Amir Tabatabaei-Dakhili; Dinesh Babu; Newton Tran; Othman Eldalal; Frederick G. West; John Ussher; Khaled H. Barakat; Richard P. Fahlman; Arno G. Siraki
err分享
err收藏
Indirect Modeling of Post-Prandial Intestinal Lymphatic Uptake of Halofantrine Using PBPK Approaches: Limitations and Implications利用PBPK方法间接模拟餐后哈尔凡特林肠道淋巴摄取：局限性及意义
errPHARMACEUTICS
IF5.5
err2025-09-22
err0
errOAAI
errYousef, Malaz; Mosa, Farag E. S.; Barakat, Khaled H.; Davies, Neal M.; Lobenberg, Raimar
err分享
err收藏
Therapeutic potential of TIM-3 inhibition in cancer, viral infections, and autoimmune disordersTIM-3抑制在癌症、病毒感染和自身免疫性疾病中的治疗潜力
errinternational journal of biochemistry cell biology
IF0
err2025-07-01
err0
PREAI
errAshira Manzoor; Khaled Barakat
err分享
err收藏
Angiostatin—a novel SARS-CoV-2 inhibitor and biomarker underlying COVID-19 pathophysiologyAngiostatin——一种新型SARS-CoV-2抑制剂和揭示COVID-19病理生理学的生物标志物
errJournal of Thrombosis and Haemostasis
IF5
err2025-04-06
err0
errOAAI
errAleksandra Franczak; Michael Joyce; Joaquin Lopez–Orozco; Holly A. Saffran; Max Saito; Amir Asgari; Subha Kalyaanamoorthy; Khaled Barakat; Tom C. Hobman; D. Lorne Tyrrell; Paul Jurasz
err分享
err收藏
The sodium/glucose cotransporter 2 inhibitor Empagliflozin inhibits long QT 3 late sodium currents in a mutation specific manner
errJOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
IF4.7
err2025-01-01
err0
errOAAI
errLunsonga, Lynn C.; Fatehi, Mohammad; Long, Wentong; Barr, Amy J.; Gruber, Brittany; Chattopadhyay, Arkapravo; Barakat, Khaled; Edwards, Andrew G.; Light, Peter E.
err分享
err收藏
Modulation of aryl hydrocarbon receptor activity by tyrosine kinase inhibitors (ponatinib and tofacitinib)
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2024-09-01
err0
errOAAI
errMosa, Farag E. S.; Alqahtani, Mohammed A.; El-Ghiaty, Mahmoud A.; El-Mahrouk, Sara R.; Barakat, Khaled; El-Kadi, Ayman O. S.
err分享
err收藏
Computational insights into the mechanisms underlying structural destabilization and recovery in trafficking-deficient hERG mutants
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2024-08-13
err0
errOAAI
errAlRawashdeh, Sara; Mosa, Farag E. S.; Barakat, Khaled H.
err分享
err收藏
Identification of aryl hydrocarbon receptor allosteric antagonists from clinically approved drugs从临床批准的药物中鉴定芳烃受体变构拮抗剂
errDRUG DEVELOPMENT RESEARCH
IF4.2
err2024-07-11
err0
errOAAI
errMosa, Farag E. S.; Alqahtani, Mohammed A.; El-Ghiaty, Mahmoud A.; Dyck, Jason R. B.; Barakat, Khaled; El-Kadi, Ayman O. S.
err分享
err收藏
Identifying novel aryl hydrocarbon receptor (AhR) modulators from clinically approved drugs: In silico screening and In vitro validation
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2024-04-01
err1
errOAAI
errMosa, Farag E. S.; Alqahtani, Mohammed A.; El-Ghiaty, Mahmoud A.; Barakat, Khaled; El-Kadi, Ayman O. S.
err分享
err收藏
Investigating the Aryl Hydrocarbon Receptor Agonist/Antagonist Conformational Switch Using Well-Tempered Metadynamics Simulations
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-03-08
err2
PREAI
errMosa, Farag E. S.; AlRawashdeh, Sara; El-Kadi, Ayman O. S.; Barakat, Khaled
err分享
err收藏
Proof of concept: Pull down assay using bovine serum albumin and an immunomodulator small molecule
errHELIYON
IF3.6
err2023-11-01
err0
errOAAI
errTabana, Yasser; Lin, Chih-Hsuan; Babu, Dinesh; Siva-Piragasam, Ramanaguru; Ponich, Ashley A.; Moon, Tae Chul; Siraki, Arno G.; Elahi, Shokrollah; Fahlman, Richard; West, Frederick G.; Barakat, Khaled
err分享
err收藏
Benchmarking of Small Molecule Feature Representations for hERG, Nav1.5, and Cav1.2 Cardiotoxicity Prediction
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-10-23
err11
errOAAI
errArab, Issar; Egghe, Kristof; Laukens, Kris; Chen, Ke; Barakat, Khaled; Bittremieux, Wout
err分享
err收藏
Target identification of small molecules: an overview of the current applications in drug discovery小分子的靶标识别: 当前在药物发现中的应用概述
errBMC BIOTECHNOLOGY
IF3.4
err2023-10-10
err24
errOAAI
errTabana, Yasser; Babu, Dinesh; Fahlman, Richard; Siraki, Arno G.; Barakat, Khaled
err分享
err收藏
16R-HETE and 16S-HETE alter human cytochrome P450 1B1 enzyme activity probably through an allosteric mechanism
errMOLECULAR AND CELLULAR BIOCHEMISTRY
IF3.7
err2023-07-12
err4
PREAI
errHidayat, Rahmat; Shoieb, Sherif M.; Mosa, Farag E. S.; Barakat, Khaled; Brocks, Dion R.; Isse, Fadumo A.; Gerges, Samar H.; El-Kadi, Ayman O. S.
err分享
err收藏
The Anticancer Potential of Psidium guajava (Guava) Extracts番石榴提取物的抗癌潜力
errLIFE-BASEL
IF3.4
err2023-01-28
err16
errOAAI
errLok, Bronwyn; Babu, Dinesh; Tabana, Yasser; Dahham, Saad Sabbar; Adam, Mowaffaq Adam Ahmed; Barakat, Khaled; Sandai, Doblin
err分享
err收藏
Rapid synthesis of bovine serum albumin-conjugated gold nanoparticles using pulsed laser ablation and their anticancer activity on hela cells
errARABIAN JOURNAL OF CHEMISTRY
IF5.2
err2023-01-01
err12
errOAAI
errAbdulateef, S. A.; Raypah, Muna E.; Omar, A. F.; Jafri, M. Z. Mat; Ahmed, Naser M.; Kaus, Noor Haida Mohd; Seeni, Azman; Mail, Mohd Hafiz; Tabana, Yasser; Ahmed, Marawan; Al Rawashdah, Sara; Barakat, Khaled
err分享
err收藏
Discovery of allosteric SHP2 inhibitors through ensemble-based consensus molecular docking, endpoint and absolute binding free energy calculations
errCOMPUTERS IN BIOLOGY AND MEDICINE
IF6.3
err2023-01-01
err2
PREAI
errJama, Maryam; Ahmed, Marawan; Jutla, Anna; Wiethan, Carson; Kumar, Jitendra; Moon, Tae Chul; West, Frederick; Overduin, Michael; Barakat, Khaled H.
err分享
err收藏

研究方向

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合作学者
合作期刊
D
David S. Wishart
H 指数: 140 · 论文数: 831
D
David H. Weinberg
H 指数: 135 · 论文数: 705
M
Michael Houghton
H 指数: 92 · 论文数: 327
J
Jason R.B. Dyck
H 指数: 90 · 论文数: 417
C
Claudio Hetz
H 指数: 89 · 论文数: 314
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