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Ichio Shimada

the university of tokyo

H指数:50

被引数:8,163

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Phase Separation Driven by Dynamic Interactions in the N-Terminal Intrinsically Disordered Region of the DEAD-Box RNA Helicase DDX3X

由DDX3X DEAD-Box RNA解旋酶N端固有无序区域动态相互作用驱动的相分离

Journal of the American Chemical Society

IF15.6

2026-05-200

PRE

Structural basis of the residence time of adenosine A2A receptor ligands revealed by NMR

由NMR揭示的腺苷A2A受体配体停留时间的结构基础

IF7.4

2025-08-290

OAAI

Real-time monitoring of the reaction of KRAS G12C mutant specific covalent inhibitor by in vitro and in-cell NMR spectroscopy

SCIENTIFIC REPORTS

IF3.9

2023-11-071

OAAI

NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-07-212

PRE

Evaluation of Drug Responses to Human β2AR Using Native Mass Spectrometry

IF4.3

2023-06-281

OAAI

Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-05-015

OAAI

Activation mechanism of the μ-opioid receptor by an allosteric modulator

变构调节剂激活 μ 阿片受体的机制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-04-1122

OAAI

Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR

IF3.6

2021-08-092

OAAI

Membrane perturbation by lipidated Atg8 underlies autophagosome biogenesis

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-07-0850

PREAI

Conformational Plasticity of Cyclic Ras‐Inhibitor Peptides Defines Cell Permeabilization Activity

Angewandte Chemie-International Edition

IF16.9

2021-02-160

PRE

Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR

NATURE COMMUNICATIONS

IF15.7

2020-10-143

OAAI

Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium

SCIENCE ADVANCES

IF12.5

2020-10-0214

OAAI

Real-Time In-Cell NMR Reveals the Intracellular Modulation of GTP-Bound Levels of RAS

IF6.9

2020-08-0121

OAAI

Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via 15N Direct Detection Nuclear Magnetic Resonance

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-05-068

PREAI

Activation of adenosine A2A receptor by lipids from docosahexaenoic acid revealed by NMR

SCIENCE ADVANCES

IF12.5

2020-03-2040

OAAI

Structural basis for two-way communication between dynein and microtubules

NATURE COMMUNICATIONS

IF15.7

2020-02-2514

OAAI

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties

NATURE COMMUNICATIONS

IF15.7

2020-01-3073

OAAI

Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor

NATURE CHEMICAL BIOLOGY

IF13.7

2020-01-2047

PREAI

Conformational equilibrium defines the variable induction of the multidrug-binding transcriptional repressor QacR

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-09-1615

OA

Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1

Ras相关的C3肉毒杆菌毒素底物1的致癌N92I突变体的构象稳定性降低

SCIENCE ADVANCES

IF12.5

2019-08-025

OAAI