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C

Cyril Bařinka

Charles University Prague

42H指数
193论文数
5.3K被引数
收录论文 80
发表时间
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Changes in the structure of mitochondrial processing peptidase driven by adaptation to anaerobiosis适应无氧环境驱动的线粒体加工肽酶结构变化
errInternational Journal of Biological Macromolecules
IF8.5
err2026-06-01
err0
PREAI
errSamad, Abdul; Ptackova, Jana; Motlova, Lucia; Kucera, Tomas; Novak, Petr; Barinka, Cyril; Cerny, Jiri; Kutejova, Eva; Cianci, Michele; Janata, Jiri; Tachezy, Jan
err分享
err收藏
Macrophage-Centric Phenotypic Screening Identifies Tetrazolone-Based HDAC6 Inhibitors That Reprogram the Tumor Immune Microenvironment and Improve Immune Checkpoint Blockade巨噬细胞中心表型筛选鉴定出能重编程肿瘤免疫微环境并改善免疫检查点阻断的tetrazolone类HDAC6抑制剂
errJournal of Medicinal Chemistry
IF6.8
err2026-05-29
err0
errOAAI
errNithya Gajendran; Manasa Suresh; Sebastian J. Marquez R.; Sruthi Mohan; Tim Ponsot; David Quiceno-Torres; Mario A. Noboa; Bryan T. Weselman; Xintang Li; Marie Durr; Zora Novakova; Mike Schutkowski; Matias Hepp; Satish Noonepalle; Cyril Barinka; Duncan J. Wardrop; Alejandro Villagra
err分享
err收藏
Cellular Target Engagement and Dissociation Kinetics of Class I-Selective Histone Deacetylase (HDAC) InhibitorsI类选择性组蛋白去乙酰化酶(HDAC)抑制剂的细胞靶点结合与解离动力学
errInternational Journal of Molecular Sciences
IF4.9
err2026-03-29
err0
errOAAI
errIrina Honin; Zora Novakova; Felix Feller; Simon Schneider; Linda Schäker-Hübner; Cyril Barinka; Finn K. Hansen
err分享
err收藏
Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases人赖氨酸脱乙酰酶对皮质动蛋白串联重复序列乙酰化的选择性靶向
errthe febs journal
IF0
err2026-02-04
err0
errOAAI
errJan Komarek; Miroslava Vosahlikova; Zsofia Kutil; Zora Novakova; Julia Kudlacova; Ruzena Tuckova; Marat Meleshin; Barbora Havlinova; Pavlina Jaklova; Jana Ptackova; Cordelia Schiene-Fischer; Mike Schutkowski; Cyril Barinka
err分享
err收藏
C-Terminal Tail Elongation Adds a New Dimension to the Tubulin CodeC端尾延伸为微管蛋白密码增添了新的维度
errCytoskeleton
IF1.6
err2026-01-01
err0
errOAAI
errCampbell, Jana; Barinka, Cyril
err分享
err收藏
Production and inhibition of human Heparan 6-O-Endosulfatase SULF1人类Heparan 6-O-Endosulfatase SULF1的生产与抑制
errGLYCOBIOLOGY
IF3.3
err2025-12-01
err0
PREAI
errAljuhani, Reem; Benicky, Julius; Panigrahi, Aswini; Mukherjee, Pritha; Sanda, Miloslav; Zhu, Shiya; Novakova, Zora; Pomin, Vitor H.; Liu, Jian; Davidson, Bruce; Barinka, Cyril; Goldman, Radoslav
err分享
err收藏
Structure–Activity Relationships (SAR) and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions结构-活性关系（SAR）与PSMA-617及其修饰脂溶性连接区域的衍生物的生物学见解
errNuclear Medicine and Biology
IF3
err2025-11-10
err0
PREAI
errMartin Schaefer; Ulrike Bauder-Wuest; Mareike Roscher; Lucia Motlová; Zsófia Kutilová; Yvonne Remde; Karel D. Klika; Jürgen Graf; Cyril Bařinka; Martina Benesova-Schaefer
err分享
err收藏
Substrate-Guided Development of HDAC11-Selective Inhibitors Featuring α-Amino Amide Zinc-Binding Groups基于底物引导的HDAC11选择性抑制剂开发：具有α-氨基酰胺锌结合基团
errACS Omega
IF4.3
err2025-10-13
err0
errOAAI
errSebastian Hilscher; Marat Meleshin; Fady Baselious; Cyril Barinka; Wolfgang Sippl; Mike Schutkowski; Cordelia Schiene-Fischer
err分享
err收藏
Mechanistic insights into TTLL11 polyglutamylase–mediated primary tubulin chain elongationTTLL11多聚谷氨酰化酶介导的原生微管蛋白链延长机制研究
errScience Advances
IF12.5
err2025-08-20
err0
PREAI
errJana Campbell; Miroslava Vosahlikova; Samar Ismail; Margareta Volnikova; Lucia Motlova; Julia Kudlacova; Kseniya Ustinova; Ivan Snajdr; Zora Novakova; Miroslav Basta; Irina Gutsche; Marie-Jo Moutin; Ambroise Desfosses; Cyril Barinka
err分享
err收藏
In silico screening of a designed focused chemical space identifies novel alkyl hydrazides as potent HDAC11 inhibitors基于计算机的筛选针对一个设计的聚焦化学空间，鉴定出新型烷基肼类化合物作为强效HDAC11抑制剂
errComputers in Biology and Medicine
IF6.3
err2025-07-04
err0
errOAAI
errFady Baselious; Sebastian Hilscher; Lukas Handke; Cyril Barinka; Mike Schutkowski; Wolfgang Sippl
err分享
err收藏
A class III ligand oscillates between internal and terminal binding modes as it engages with the Dishevelled PDZ domainIII类配体在与无序蛋白PDZ结构域相互作用时，在内部结合模式和末端结合模式之间振荡。
errStructure
IF4.3
err2025-06-13
err0
PREAI
errJitender Kumar; Miroslav Micka; Jan Komárek; Tomáš Klumpler; Vojtěch Bystrý; Remco Sprangers; Cyril Bařinka; Vítězslav Bryja; Konstantinos Tripsianes
err分享
err收藏
Retinitis pigmentosa-linked mutations impair the snRNA unwinding activity of SNRNP200 and reduce pre-mRNA binding of PRPF8
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2025-03-05
err0
errOAAI
errZimmann, Felix; Mcnicoll, Francois; Thakur, Prasoon Kumar; Blazikova, Michaela; Kubovciak, Jan; Canas, Maria Clara Hernandez; Novakova, Zora; Barinka, Cyril; Kolar, Michal; Stanek, David; Mueller-McNicoll, Michaela; Cvackova, Zuzana
err分享
err收藏
Structure-Activity Relationships and Biological Insights into PSMA-617 and Its Derivatives with Modified Lipophilic Linker Regions
errACS OMEGA
IF4.3
err2025-02-12
err0
errOAAI
errSchafer, Martin; Bauder-Wust, Ulrike; Roscher, Mareike; Motlova, Lucia; Kutilova, Zsofia; Remde, Yvonne; Klika, Karel D.; Graf, Jurgen; Barinka, Cyril; Benesova-Schafer, Martina
err分享
err收藏
Optical and MRI-Guided Theranostic Application of Ultrasmall Superparamagnetic Iron Oxide Nanodrug Conjugate for PSMA-Positive Prostate Cancer Therapy光学和MRI引导的超小超顺磁性氧化铁纳米药物偶联物在PSMA阳性前列腺癌治疗中的诊疗应用
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2025-02-11
err0
PREAI
errSurasinghe, S; Liatsou, I; Nováková, Z; Barinka, C; Artemov, D; Hapuarachchige, S
err分享
err收藏
Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-10-01
err0
errOAAI
errScheuerer, Simon; Motlova, Lucia; Schaeker-Huebner, Linda; Sellmer, Andreas; Feller, Felix; Ertl, Fabian J.; Koch, Pierre; Hansen, Finn K.; Barinka, Cyril; Mahboobi, Siavosh
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err收藏
Carboxy-terminal polyglutamylation regulates signaling and phase separation of the Dishevelled protein羧基末端多谷氨酸化调节蓬乱蛋白的信号传导和相分离
errEMBO JOURNAL
IF8.3
err2024-09-30
err0
errOAAI
errKravec, Marek; Sedo, Ondrej; Nedvedova, Jana; Micka, Miroslav; Sulcova, Marie; Zezula, Nikodem; Gomoryova, Kristina; Potesil, David; Sri Ganji, Ranjani; Bologna, Sara; Cervenka, Igor; Zdrahal, Zbynek; Harnos, Jakub; Tripsianes, Konstantinos; Janke, Carsten; Barinka, Cyril; Bryja, Vitezslav
err分享
err收藏
Multistep allelic conversion in mouse pre-implantation embryos by AAV vectors
errSCIENTIFIC REPORTS
IF3.9
err2024-08-29
err0
errOAAI
errNickl, Petr; Jenickova, Irena; Elias, Jan; Kasparek, Petr; Barinka, Cyril; Kopkanova, Jana; Sedlacek, Radislav
err分享
err收藏
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2024-07-01
err0
errOAAI
errPanigrahi, Aswini; Benicky, Julius; Aljuhani, Reem; Mukherjee, Pritha; Novakova, Zora; Barinka, Cyril; Goldman, Radoslav
err分享
err收藏
Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-01-15
err0
errOAAI
errNovakova, Zora; Tehrani, Zahra Aliakbar; Jurok, Radek; Motlova, Lucia; Kutil, Zsofia; Pavlicek, Jiri; Shukla, Shivam; Choy, Cindy J.; Havlinova, Barbora; Baranova, Petra; Berkman, Clifford E.; Kuchar, Martin; Cerny, Jiri; Barinka, Cyril
err分享
err收藏
Uncovering the essential roles of glutamate carboxypeptidase 2 orthologs in Caenorhabditis elegans
errBIOSCIENCE REPORTS
IF4.7
err2024-01-12
err1
errOAAI
errPanska, Lucie; Nedvedova, Stepanka; Vacek, Vojtech; Krivska, Daniela; Konecny, Lukas; Knop, Filip; Kutil, Zsofia; Skultetyova, Lubica; Leontovyc, Adrian; Ulrychova, Lenka; Sakanari, Judy; Asahina, Masako; Barinka, Cyril; Macurkova, Marie; Dvorak, Jan
err分享
err收藏

研究方向

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