Mark D. Distefano - Publications, H-index & Citations

Mark D. Distefano

university of minnesota

46H指数

235论文数

7.5K被引数

收录论文 73

发表时间

Farnesyltransferase Enables Modular Assembly of Dual-Functional Nanobody Conjugates for in Vivo Imaging of Inflammation 法尼基转移酶实现双功能纳米抗体偶联物的模块化组装，用于体内炎症成像

Angewandte Chemie-International Edition

IF16.9

2026-08-28

OAAI

Sneha Venkatachalapathy; Yoon Ho Lee; Ali Salehi Farid; Heydar Moravej; Sina Djafari Rouhani; Jennifer E. Rowley; Mohammad Rashidian; Mark D. Distefano

NEK7 Cys298 is important for NLRP3 inflammasome and targetable by dimethyl fumarate NEK7 Cys298对NLRP3炎性小体至关重要且可被二甲基富马酸靶向

Cell Chemical Biology

IF7.2

2026-04-21

OAAI

Yandong Zhang; Helena Lindner; Brian So; Zirong Chen; Haoyang Li; Jiashu Xu; Jiahe Wang; Jie Xu; Alexandru M. Petre; Mark D. Distefano; Gabriel Núñez; Hening Lin

Organotellurium Probes Enable One-step Single-cell Analysis of Post-translational Modification 有机碲探针实现翻译后修饰的单细胞一步分析

Journal of the American Chemical Society

IF15.6

2026-02-17

OAAI

Yuanzhe Chen; Kris Elbein; Sneha Venkatachalapathy; Ellen L. Lorimer; Andrea M. Sprague-Getsy; Shelby A. Auger; Zoë A. Maxwell; Mohammad Rashidian; James L. Hougland; Carol L. Williams; Edgar A. Arriaga; Mark D. Distefano

In Vivo Metabolic Labeling with an Isoprenoid Probe Reveals APOE Allele-Specific Differences in the Prenylome 体内代谢标记使用类异戊二烯探针揭示了APOE等位基因特异性的前烯酰化物组差异

ACS Chemical Biology

IF3.8

2025-08-06

PREAI

Alexandru M. Petre; Josslen S. Thieschafer; Charuta Palsuledesai; Katie Cornille; Allison Chang; Ling Li; Mark D. Distefano

Targeted Drug Delivery by MMAE Farnesyl-Bioconjugated Multivalent Chemically Self-Assembled Nanorings Induces Potent Receptor-Dependent Immunogenic Cell Death

BIOCONJUGATE CHEMISTRY

IF3.9

2024-05-03

PREAI

Wang, Yiao; Kilic, Ozgun; Rozumalski, Lakmal; Distefano, Mark D.; Wagner, Carston R.

Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry

BIOCONJUGATE CHEMISTRY

IF3.9

2024-04-24

PREAI

Auger, Shelby A.; Venkatachalapathy, Sneha; Suazo, Kiall Francis G.; Wang, Yiao; Sarkis, Alexander W.; Bernhagen, Kaitlyn; Justyna, Katarzyna; Schaefer, Jonas V.; Wollack, James W.; Plu''ckthun, Andreas; Li, Ling; Distefano, Mark D.

Multivalent Fluorinated Nanorings for On-Cell 19F NMR

BIOMACROMOLECULES

IF5.4

2024-01-22

OAAI

Li, Jiaqian; Wang, Yiao; Distefano, Mark. D.; Wagner, Carston R.; Pomerantz, William C. K.

Orthogonal Enzyme-Substrate Design Strategy for Discovery of Human Protein Palmitoyltransferase Substrates

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-09-29

OAAI

Puthenveetil, Robbins; Auger, Shelby A.; Gomez-Navarro, Natalia; Rana, Mitra Shumsher; Das, Riki; Healy, Liam Brendan; Suazo, Kiall F.; Shi, Zhen-Dan; Swenson, Rolf E.; Distefano, Mark D.; Banerjee, Anirban

Synthesis, Enzymatic Peptide Incorporation, and Applications of Diazirine-Containing Isoprenoid Diphosphate Analogues

ORGANIC LETTERS

IF5

2023-09-05

OAAI

Justyna, Katarzyna; Das, Riki; Lorimer, Ellen L.; Hu, Jiayue; Pedersen, Jodi S.; Sprague-Getsy, Andrea M.; Schey, Garrett L.; Sieburg, Michelle A.; Koehn, Olivia J.; Wang, Yen-Chih; Chen, Yong-Xiang; Hougland, James L.; Williams, Carol L.; Distefano, Mark D.

Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting

MBIO

IF4.7

2023-08-07

OAAI

Wang, Qiang-Qiang; Sun, Ming; Tang, Tao; Lai, De-Hua; Liu, Jing; Maity, Sanjay; He, Kai; Wu, Xi-Ting; Yang, Jiong; Li, Yue-Bao; Tang, Xiao-Yan; Ding, Hui-Yong; Hide, Geoff; Distefano, Mark; Lun, Zhao-Rong; Zhu, Xing-Quan; Long, Shaojun

GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-06-01

OAAI

Koehn, Olivia J.; Lorimer, Ellen; Unger, Bethany; Harris, Ra'Mal; Das, Akansha S.; Suazo, Kiall F.; Auger, Shelby A.; Distefano, Mark D.; Prokop, Jeremy W.; Williams, Carol L.

Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities

NATURE COMMUNICATIONS

IF15.7

2023-05-13

OAAI

Petenkova, Anastasiia; Auger, Shelby A.; Lamb, Jeffrey; Quellier, Daisy; Carter, Cody; To, On Tak; Milosevic, Jelena; Barghout, Rana; Kugadas, Abirami; Lu, Xiaoxiao; Geddes-McAlister, Jennifer; Fichorova, Raina; Sykes, David B.; Distefano, Mark D.; Gadjeva, Mihaela

Thinking outside the CaaX-box: an unusual reversible prenylation on ALDH9A1 在caax-box之外思考: ALDH9A1上不寻常的可逆异戊二烯化

RSC CHEMICAL BIOLOGY

IF3.1

2023-01-01

OAAI

Suazo, Kiall F.; Belicek, Jakub; Schey, Garrett L.; Auger, Shelby A.; Petre, Alexandru M.; Li, Ling; Blazewska, Katarzyna M.; Kopecny, David; Distefano, Mark D.

Engineering Biomimetic Trogocytosis with Farnesylated Chemically Self-Assembled Nanorings

BIOMACROMOLECULES

IF5.4

2022-11-23

OAAI

Wang, Yiao; Rozumalski, Lakmal; Kilic, Ozgun; Lichtenfels, Caitlin; Petersberg, Jacob; Distefano, Mark D.; Wagner, Carston R.

Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-10-11

OAAI

Wang, You; Xu, Feng; Nichols, Connie B.; Shi, Yuqian; Hellinga, Homme W.; Alspaugh, J. Andrew; Distefano, Mark D.; Beese, Lorena S.

Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation

ACS CHEMICAL BIOLOGY

IF3.8

2022-10-04

OAAI

Morstein, Johannes; Bader, Taysir; Cardillo, Ariana L.; Schackmann, Julian; Ashok, Sudhat; Hougland, James L.; Hrycyna, Christine A.; Trauner, Dirk H.; Distefano, Mark D.

In Vivo Prenylomic Profiling in the Brain of a Transgenic Mouse Model of Alzheimer's Disease Reveals Increased Prenylation of a Key Set of Proteins 阿尔茨海默氏病转基因小鼠模型大脑中的体内异戊二烯谱分析揭示了一组关键蛋白质的异戊二烯化增加

ACS CHEMICAL BIOLOGY

IF3.8

2022-09-15

OAAI

Jeong, Angela; Auger, Shelby A.; Maity, Sanjay; Fredriksen, Kristina; Zhong, Rui; Li, Ling; Distefano, Mark D.

Manipulating Cell Fates with Protein Conjugates

BIOCONJUGATE CHEMISTRY

IF3.9

2022-08-15

OAAI

Wang, Yiao; Wagner, Carston R.; Distefano, Mark D.

Combining Isoprenoid Probes with Antibody Markers for Mass Cytometric Analysis of Prenylation in Single Cells

ANALYTICAL CHEMISTRY

IF6.7

2022-08-11

OAAI

Maxewell, Zoe A.; Suazo, Kiall F.; Brown, Heather M. G.; Distefano, Mark D.; Arriaga, Edgar A.

Directed cell migration towards softer environments 定向细胞向较软的环境迁移

NATURE MATERIALS

IF38.5

2022-07-11

111

PREAI

Isomursu, Aleksi; Park, Keun-Young; Hou, Jay; Cheng, Bo; Mathieu, Mathilde; Shamsan, Ghaidan A.; Fuller, Benjamin; Kasim, Jesse; Mahmoodi, M. Mohsen; Lu, Tian Jian; Genin, Guy M.; Xu, Feng; Lin, Min; Distefano, Mark D.; Ivaska, Johanna; Odde, David J.

研究方向