Robert Blumenthal - Publications, H-index & Citations

Robert Blumenthal

national institutes of health (nih) - usa

70H指数

340论文数

2.0W被引数

收录论文 80

发表时间

Inhibition of Clostridioides difficile-Specific DNA Adenine Methyltransferase CamA by Analogs of S-Adenosyl-l-methionine S-腺苷-l-蛋氨酸类似物对Clostridioides difficile特异性DNA腺嘌呤甲基转移酶CamA的抑制

ACS Omega

IF4.3

2025-11-17

OAAI

Jujun Zhou; Youchao Deng; Dan Yu; Taraneh Hajian; Masoud Vedadi; Xing Zhang; Robert M. Blumenthal; Rong Huang; Xiaodong Cheng

Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs 多聚体转录因子BCL11A利用两个锌指串联阵列结合成簇的短序列基序

NATURE COMMUNICATIONS

IF15.7

2025-04-17

OAAI

Horton, John R.; Yu, Meigen; Zhou, Jujun; Tran, Melody; Anakal, Rithvi R.; Lu, Yue; Blumenthal, Robert M.; Zhang, Xiaotian; Huang, Yun; Zhang, Xing; Cheng, Xiaodong

Quinoline-based compounds can inhibit diverse enzymes that act on DNA

CELL CHEMICAL BIOLOGY

IF7.2

2024-12-01

OAAI

Zhou, Jujun; Chen, Qin; Ren, Ren; Yang, Jie; Liu, Bigang; Horton, John R.; Chang, Caleb; Li, Chuxuan; Maksoud, Leora; Yang, Yifei; Rotili, Dante; Jain, Abhinav K.; Zhang, Xing; Blumenthal, Robert M.; Chen, Taiping; Gao, Yang; Valente, Sergio; Mai, Antonello; Cheng, Xiaodong

DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations

NUCLEIC ACIDS RESEARCH

IF13.1

2024-09-26

OAAI

Zhang, Xing; Blumenthal, Robert M.; Cheng, Xiaodong

Updated understanding of the protein-DNA recognition code used by C2H2 zinc finger proteins

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2024-08-01

OAAI

Zhang, Xing; Blumenthal, Robert M.; Cheng, Xiaodong

A growth-based assay using fluorescent protein emission to screen for S-adenosylmethionine synthetase inhibitors

DRUG DEVELOPMENT RESEARCH

IF4.2

2023-10-11

OAAI

Viola, Ronald E.; Parungao, Gwenn G.; Blumenthal, Robert M.

Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-08-01

OAAI

Zhou, Jujun; Horton, John R.; Kaur, Gundeep; Chen, Qin; Li, Xuwen; Mendoza, Fabian; Wu, Tao; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Structures of CTCF-DNA complexes including all 11 zinc fingers

NUCLEIC ACIDS RESEARCH

IF13.1

2023-07-13

OAAI

Yang, Jie; Horton, John R.; Liu, Bin; Corces, Victor G.; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase

ACS CHEMICAL BIOLOGY

IF3.8

2023-02-22

OAAI

Zhou, Jujun; Deng, Youchao; Iyamu, Iredia D.; Horton, John R.; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Rotili, Dante; Mai, Antonello; Blumenthal, Robert M.; Zhang, Xing; Huang, Rong; Cheng, Xiaodong

Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-02-01

OAAI

Ren, Ren; Horton, John R.; Chen, Qin; Yang, Jie; Liu, Bin; Huang, Yun; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410-DNA interaction using small angle X-ray scattering

NUCLEIC ACIDS RESEARCH

IF13.1

2023-01-20

OAAI

Kaur, Gundeep; Ren, Ren; Hammel, Michal; Horton, John R.; Yang, Jie; Cao, Yu; He, Chenxi; Lan, Fei; Lan, Xianjiang; Blobel, Gerd A.; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-12-29

OAAI

Zhou, Jujun; Horton, John R.; Menna, Martina; Fiorentino, Francesco; Ren, Ren; Yu, Dan; Hajian, Taraneh; Vedadi, Masoud; Mazzoccanti, Giulia; Ciogli, Alessia; Weinhold, Elmar; Hueben, Michael; Blumenthal, Robert M.; Zhang, Xing; Mai, Antonello; Rotili, Dante; Cheng, Xiaodong

Mediating and maintaining methylation while minimizing mutation: Recent advances on mammalian DNA methyltransferases

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2022-08-01

OAAI

Cheng, Xiaodong; Blumenthal, Robert M.

Differential ETS1 binding to T:G mismatches within a CpG dinucleotide contributes to C-to-T somatic mutation rate of the IDH2 hotspot at codon Arg140

DNA REPAIR

IF2.7

2022-05-01

OAAI

Yang, Jie; Gupta, Esha; Horton, John R.; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Enzymatic characterization of mRNA cap adenosine-N6 methyltransferase PCIF1 activity on uncapped RNAs

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-04-01

OAAI

Yu, Dan; Dai, Nan; Wolf, Eric J.; Correa, Ivan R., Jr.; Zhou, Jujun; Wu, Tao; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Clostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix

NATURE COMMUNICATIONS

IF15.7

2021-06-08

OAAI

Zhou, Jujun; Horton, John R.; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions

NUCLEIC ACIDS RESEARCH

IF13.1

2021-06-04

OAAI

Yu, Dan; Horton, John R.; Yang, Jie; Hajian, Taraneh; Vedadi, Masoud; Sagum, Cari A.; Bedford, Mark T.; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations

NUCLEIC ACIDS RESEARCH

IF13.1

2021-04-20

OAAI

Yang, Jie; Horton, John R.; Akdemir, Kadir C.; Li, Jia; Huang, Yun; Kumar, Janani; Blumenthal, Robert M.; Zhang, Xing; Cheng, Xiaodong

A Role for N6-Methyladenlne in DNA Damage Repair

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2021-03-01

OAAI

Zhang, Xing; Blumenthal, Robert M.; Cheng, Xiaodong