William F. Heinz - Publications, H-index & Citations

William F. Heinz

National Cancer Institute

18H指数

105论文数

1.8K被引数

收录论文 30

发表时间

NOS2 and COX2 impact the spatial landscape of CD8+ T cells in ER- breast cancer, providing novel mechanistic insight that drives tumor progression and poor survival NOS2和COX2影响ER-乳腺癌中CD8+ T细胞的时空景观，为驱动肿瘤进展和不良生存提供了新的机制见解

Redox Biology

IF11.9

2026-04-27

OAAI

Lisa A. Ridnour; Robert Y.S. Cheng; William F. Heinz; Leandro L. Coutinho; Erika M. Palmieri; M.Cristina Rangel; Stephen K. Anderson; Daniel W. McVicar; Stephen M. Hewitt; Stephen T.C. Wong; Xiaoxian Li; Stefan Ambs; Timothy R. Billiar; Sharon A. Glynn; Jenny C. Chang; Stephen J. Lockett; David A. Wink

SCaN: A Screening and Characterization Platform for Nanosuspensions Enables In Vivo Delivery of a Crystalline hRpn13Pru Degrader

ACS Pharmacology & Translational Science

IF3.7

2026-01-22

PREAI

Christine S. Brugger-Muli; Snehal M. Gaikwad; Wendy du Bois; Venkata R. Sabbasani; Rolf E. Swenson; William F. Heinz; Tyler J. Peat; Beverly A. Mock; Kylie J. Walters

Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors

JCI INSIGHT

IF6.1

2024-05-21

OAAI

Ridnour, Lisa A.; Cheng, Robert Y. S.; Kedei, Noemi; Somasundaram, Veena; Bhattacharyya, Dibyangana D.; Basudhar, Debashree; Wink, Adelaide L.; Walke, Abigail J.; Kim, Caleb; Heinz, William F.; Edmondson, Elijah F.; Butcher, Donna O.; Warner, Andrew C.; Dorsey, Tiffany H.; Pore, Milind; Kinders, Robert J.; Lipkowitz, Stanley; Bryant, Richard J.; Rittscher, Jens; Wong, Stephen T. C.; Hewitt, Stephen M.; Chang, Jenny C.; Shalaby, Aliaa; Callagy, Grace M.; Glynn, Sharon A.; Ambs, Stefan; Anderson, Stephen K.; McVicar, Daniel W.; Lockett, Stephen J.; Wink, David A.

Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells (vol 6, 712, 2023)

COMMUNICATIONS BIOLOGY

IF5.1

2023-07-27

OAAI

Ahn, Jong Il; Zhang, Liang; Ravishankar, Harsha; Fan, Lixin; Kirsch, Klara; Zeng, Yan; Meng, Lingjun; Park, Jung-Eun; Yun, Hye-Yeoung; Ghirlando, Rodolfo; Ma, Buyong; Ball, David; Ku, Bonsu; Nussinov, Ruth; Schmit, Jeremy D.; Heinz, William F.; Kim, Seung Jun; Karpova, Tatiana; Wang, Yun-Xing; Lee, Kyung S.

Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells

COMMUNICATIONS BIOLOGY

IF5.1

2023-07-11

OAAI

Interferon-gamma is quintessential for NOS2 and COX2 expression in ER- breast tumors that lead to poor outcome

CELL DEATH & DISEASE

IF9.6

2023-05-11

OAAI

Cheng, Robert Y. S.; Ridnour, Lisa A.; Wink, Adelaide L.; Gonzalez, Ana L.; Femino, Elise L.; Rittscher, Helene; Somasundaram, Veena; Heinz, William F.; Coutinho, Leandro; Rangel, M. Cristina; Edmondson, Elijah F.; Butcher, Donna; Kinders, Robert J.; Li, Xiaoxian; Wong, Stephen T. C.; McVicar, Daniel W.; Anderson, Stephen K.; Pore, Milind; Hewitt, Stephen M.; Billiar, Timothy R.; Glynn, Sharon A.; Chang, Jenny C.; Lockett, Stephen J.; Ambs, Stefan; Wink, David A.

Interferon-gamma induces NOS2 and COX2 in ER-breast cancer that drives increase metastatic potential

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Cheng, Yuk Sing Robert; Ridnour, Lisa; Walke, Abigail; Kedei, Noemi; Wink, Adelaide; Edmonston, Elijah; Butcher, Donna; Dorsey, Tiffany; Heinz, William; Bryant, Richard; Kinders, Robert; Lipkowitz, Stanley; Wong, Stephen; Pore, Milind; Hewitt, Stephen; McVicar, Daniel; Anderson, Stephen; Chang, Jenny; Ambs, Stefan; Lockett, Stephen; Wink, David

Developing methods to study conformational changes in RNA crystals using a photocaged ligand

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-08-16

OAAI

Lee, Hyun Kyung; Conrad, Chelsie E. E.; Magidson, Valentin; Heinz, William F. F.; Pauly, Gary; Yu, Ping; Ramakrishnan, Saminathan; Stagno, Jason R. R.; Wang, Yun-Xing

Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates

CURRENT BIOLOGY

IF7.5

2021-11-01

OAAI

Trofka, Anna; Huang, Bau-Lin; Zhu, Jianjian; Heinz, William F.; Magidson, Valentin; Shibata, Yuki; Shi, Yun-Bo; Tarchini, Basile; Stadler, H. Scott; Kabangu, Mirindi; Baddar, Nour W. Al Haj; Voss, S. Randal; Mackem, Susan

An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients 基于活细胞产生的氧气和营养梯度的体外肿瘤发生模型

COMMUNICATIONS BIOLOGY

IF5.1

2021-04-15

OAAI

Gilmore, Anne C.; Flaherty, Sarah J.; Somasundaram, Veena; Scheiblin, David A.; Lockett, Stephen J.; Wink, David A.; Heinz, William F.

Synchronous RNA conformational changes trigger ordered phase transitions in crystals

NATURE COMMUNICATIONS

IF15.7

2021-03-19

OAAI

Ramakrishnan, Saminathan; Stagno, Jason R.; Conrad, Chelsie E.; Ding, Jienyu; Yu, Ping; Bhandari, Yuba R.; Lee, Yun-Tzai; Pauly, Gary; Yefanov, Oleksandr; Wiedorn, Max O.; Knoska, Juraj; Oberthuer, Dominik; White, Thomas A.; Barty, Anton; Mariani, Valerio; Li, Chufeng; Brehm, Wolfgang; Heinz, William F.; Magidson, Valentin; Lockett, Stephen; Hunter, Mark S.; Boutet, Sebastien; Zatsepin, Nadia A.; Zuo, Xiaobing; Grant, Thomas D.; Pandey, Suraj; Schmidt, Marius; Spence, John C. H.; Chapman, Henry N.; Wang, Yun-Xing

Characterizing and circumventing sequence restrictions for synthesis of circular RNA in vitro

NUCLEIC ACIDS RESEARCH

IF13.1

2021-01-06

OAAI

Rausch, Jason W.; Heinz, William F.; Payea, Matthew J.; Sherpa, Chringma; Gorospe, Myriam; Le Grice, Stuart F. J.

Truncated tetrahedral RNA nanostructures exhibit enhanced features for delivery of RNAi substrates

NANOSCALE

IF5.1

2020-01-01

PREAI

Zakrevsky, Paul; Kasprzak, Wojciech K.; Heinz, William F.; Wu, Weimin; Khant, Htet; Bindewald, Eckart; Dorjsuren, Nomongo; Fields, Eric A.; de Val, Natalia; Jaeger, Luc; Shapiro, Bruce A.

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

CELL CHEMICAL BIOLOGY

IF7.2

2019-08-01

OAAI

Matarlo, Joe S.; Krumpe, Lauren R. H.; Heinz, William F.; Oh, Daniel; Shenoy, Shilpa R.; Thomas, Cheryl L.; Goncharova, Ekaterina I.; Lockett, Stephen J.; O'Keefe, Barry R.

Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli

NUCLEIC ACIDS RESEARCH

IF13.1

2019-03-07

OAAI

Sun, Zhe; Cagliero, Cedric; Izard, Jerome; Chen, Yixiong; Zhou, Yan Ning; Heinz, William F.; Schneider, Thomas D.; Jin, Ding Jun

Restricting Diffusive Exchange In Vitro Demonstrates Inos Modulates Hypoxic Gradients in the Tumor Microenvironment

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

OAAI

Gilmore, Caroline; Somasundaram, Veena; Scheiblin, David; Heinz, William; Lockett, Stephen; Wink, David

Brilliant blue, green, yellow, and red fluorescent diamond particles: synthesis, characterization, and multiplex imaging demonstrations

NANOSCALE

IF5.1

2019-01-01

OAAI

Nunn, Nicholas; Prabhakar, Neeraj; Reineck, Philipp; Magidson, Valentin; Kamiya, Erina; Heinz, William F.; Torelli, Marco D.; Rosenholm, Jessica; Zaitsev, Alexander; Shenderova, Olga

Role of NOS2-COX2 crosstalk in tumor microenvironment of estrogen receptor-negative breast cancer and its therapeutic implications

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Basudhar, Debashree; Glynn, Sharon; Greer, Madison; Somasundaram, Veena; No, Jae H.; Scheiblin, David A.; Garrido, Pablo; Heinz, William F.; Ryan, Aideen E.; Weiss, Jonathan M.; Cheng, Robert Y.; Ridnour, Lisa A.; Lockett, Stephen J.; McVicar, Daniel W.; Ambs, Stefan; Wink, David A.

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer NOS2和COX2的共表达可加速肿瘤生长并降低雌激素受体阴性乳腺癌的生存率

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-10-27

OAAI

Basudhar, Debashree; Glynn, Sharon A.; Greer, Madison; Somasundaram, Veena; No, Jae Hong; Scheiblin, David A.; Garrido, Pablo; Heinz, William F.; Ryan, Aideen E.; Weiss, Jonathan M.; Cheng, Robert Y. S.; Ridnour, Lisa A.; Lockett, Stephen J.; McVicar, Daniel W.; Ambs, Stefan; Wink, David A.

Restricted Exchange Environment Chambers for Creating and Manipulating Diffusive Gradients in 2D Cell Culture

BIOPHYSICAL JOURNAL

IF3.1

2015-01-01

OAAI

Heinz, William F.; Werbin, Jeffrey; Hoh, Jan H.

研究方向