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Xiang Fu

st jude childrens research hospital
H指数:8
被引数:403

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Structure-Activity Relationship of Potent, Selective, and Orally Bioavailable Molecular Glue Degraders of CK1α

CK1α 的有效，选择性和口服生物利用度分子胶降解剂的构效关系

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2024-09-121
PRE
Nishiguchi, Gisele; Caine, Elizabeth A.; Mcgowan, Kevin; Shi, Zhe; Aggarwal, Anup; Mayasundari, Anand; Price, Jeanine; Yang, Lei; Li, Yong; Fu, Xiang; Mascibroda, Lauren G.; Das, Sourav; Daniels, Danette L.; Urh, Marjeta; Klco, Jeffery M.; Riching, Kristin M.; Rankovic, Zoran
Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells
NATURE BIOMEDICAL ENGINEERING
IF26.6
2023-10-055
PRE
Stepanov, Alexey V.; Xie, Jia; Zhu, Qiaoqiao; Shen, Zuyuan; Su, Wenji; Kuai, Letian; Soll, Richard; Rader, Christoph; Shaver, Geramie; Douthit, Lacey; Zhang, Ding; Kalinin, Roman; Fu, Xiang; Zhao, Yingying; Qin, Tian; Baran, Phil S.; Gabibov, Alexander G.; Bushnell, David; Neri, Dario; Kornberg, Roger D.; Lerner, Richard A.
From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2023-05-015
OAAI
Koravovic, Mladen; Mayasundari, Anand; Tasic, Gordana; Keramatnia, Fatemeh; Stachowski, Timothy R.; Cui, Huarui; Chai, Sergio C.; Jonchere, Barbara; Yang, Lei; Li, Yong; Fu, Xiang; Hiltenbrand, Ryan; Paul, Leena; Mishra, Vibhor; Klco, Jeffery M.; Roussel, Martine F.; Pomerantz, William CK.; Fischer, Marcus; Rankovic, Zoran; Savic, Vladimir
Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

苯基戊二酰亚胺: 用于PROTACs设计的替代cerebon粘合剂

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2021-11-1678
OA
Min, Jaeki; Mayasundari, Anand; Keramatnia, Fatemeh; Jonchere, Barbara; Yang, Seung Wook; Jarusiewicz, Jamie; Actis, Marisa; Das, Sourav; Young, Brandon; Slavish, Jake; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H.; Yun, Mi-Kyung; Li, Zhenmei; Nithianantham, Stanley; Chai, Sergio; Chen, Taosheng; Shelat, Anang; Lee, Richard E.; Nishiguchi, Gisele; White, Stephen W.; Roussel, Martine F.; Potts, Patrick Ryan; Fischer, Marcus; Rankovic, Zoran
Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-05-2763
OAAI
Nishiguchi, Gisele; Keramatnia, Fatemeh; Min, Jaeki; Chang, Yunchao; Jonchere, Barbara; Das, Sourav; Actis, Marisa; Price, Jeanine; Chepyala, Divyabharathi; Young, Brandon; McGowan, Kevin; Slavish, P. Jake; Mayasundari, Anand; Jarusiewicz, Jamie A.; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H.; Papizan, James B.; Kodali, Kiran; Peng, Junmin; Miller, Shondra M. Pruett; Roussel, Martine F.; Mullighan, Charles; Fischer, Marcus; Rankovic, Zoran
Ag-Catalyzed Formal [2 + 4] Cycloaddition for the Diastereoselective Synthesis of Sterically Hindered 4-Aminochroman-2-ones from α-Diazopyrazoleamides and o-Hydroxy Aldimines

Ag催化下形式[2 + 4]环加成反应，用于从α-重氮基吡唑酰胺和邻羟基醛亚胺合成空间位阻的4-氨基色满-2-酮的对映非对映异构体选择性合成。

The Journal of Organic Chemistry
IF0
0
PRE
Pei Li; Maoqing Shi; Kaixin Yang; Kongxi Qiu; Zhonghui Zhang; Yaxin Li; Xiaoyan Yang; Xiang Fu; Ji Zhang; Wenhao Hu; Yu Qian

研究方向

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Y
Yong Li
H 指数:27论文数:115被引数:4,538
Z
Zoran Ranković
H 指数:30论文数:219被引数:6,139
G
Gisele Nishiguchi
H 指数:19论文数:68被引数:1,988
L
Lei Yang
H 指数:32论文数:113被引数:2,942
A
Anand Mayasundari
H 指数:19论文数:74被引数:1,554
J
Jamie Jarusiewicz
H 指数:11论文数:28被引数:708
胡
胡文浩
H 指数:60论文数:993被引数:1.4万
M
Marisa Actis
H 指数:10论文数:33被引数:560
王
王海青
H 指数:42论文数:225被引数:5,211
M
Martine F. Roussel
H 指数:96论文数:653被引数:3.7万