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Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain Kumar, Jay Prakash; Kosek, Dalibor; Durell, Stewart R.; Jenkins, Lisa M. Miller; Debnath, Subrata; Coussens, Nathan P.; Hall, Matthew D.; Appella, Daniel H.; Dyda, Fred; Mazur, Sharlyn J.; Appella, Ettore 分享 收藏
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Alkyl-substituted N-methylaryl-N′-aryl-4-aminobenzamides: A new series of small molecule inhibitors for Wip1 phosphatase Robello, Marco; Zheng, Hongchao; Saha, Mrinmoy; Rosenker, Kara M. George; Debnath, Subrata; Kumar, Jay Prakash; Tagad, Harichandra D.; Mazur, Sharlyn J.; Appella, Ettore; Appella, Daniel H. 分享 收藏
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An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes Hait, Sabrina Helmold; Hogge, Christopher James; Rahman, Mohammad Arif; Ko, Eun-Ju; Hunegnaw, Ruth; Mushtaq, Zuena; Enyindah-Asonye, Gospel; Hoang, Tanya; Jenkins, Lisa M. Miller; Appella, Ettore; Appella, Daniel H.; Robert-Guroff, Marjorie 分享 收藏
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Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens Clausse, Victor; Tao, Dingyin; Debnath, Subrata; Fang, Yuhong; Tagad, Harichandra D.; Wang, Yuhong; Sun, Hongmao; LeClair, Christopher A.; Mazur, Sharlyn J.; Lane, Kelly; Shi, Zhen-Dan; Vasalatiy, Olga; Eells, Rebecca; Baker, Lynn K.; Henderson, Mark J.; Webb, Martin R.; Shen, Min; Hall, Matthew D.; Appella, Ettore; Appella, Daniel H.; Coussens, Nathan P. 分享 收藏
The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target Nikolayevskiy, Herman; Robello, Marco; Scerba, Michael T.; Pasternak, Evan H.; Saha, Mrinmoy; Hartman, Tracy L.; Buchholz, Caitlin A.; Buckheit, Robert W., Jr.; Durell, Stewart R.; Appella, Daniel H. 分享 收藏
Allosteric modulation of β-cell M3 muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice Zhu, Lu; Rossi, Mario; Cohen, Amanda; Pham, Jonathan; Zheng, Hongchao; Dattaroy, Diptadip; Mukaibo, Taro; Melvin, James E.; Langel, Jennifer L.; Hattar, Samer; Matschinsky, Franz M.; Appella, Daniel H.; Doliba, Nicolai M.; Wess, Jurgen 分享 收藏
Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator Jenkins, Lisa M. Miller; Paine, Elliott L.; Deshmukh, Lalit; Nikolayevskiy, Herman; Lyons, Gaelyn C.; Scerba, Michael T.; Rosenker, Kara George; Luecke, Hans F.; Louis, John M.; Chertova, Elena; Gorelick, Robert J.; Ott, David E.; Clore, G. Marius; Appella, Daniel H. 分享 收藏
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