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Daniel H. Appella

national institute of diabetes and digestive and kidney diseases

33H指数
149论文数
5.2K被引数
收录论文 73
发表时间
Bioorthogonal peptide nucleic acids with five-membered rings
err2026-07-23
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errOAAI
errHarsha Amarasekara; Riley F. Lehman; Hongchao Zheng; Daniel H. Appella
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RNA detection on a microfluidic platform using Thyclotides.基于Thyclotides的微流控平台RNA检测。
err2025-11-26
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errHarsha Amarasekara; Riley Lehman; Paniz Rezvan Sangsari; Nicole Y. Morgan; Brian O'Farrell; Daniel H. Appella
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Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain
err2024-08-01
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errKumar, Jay Prakash; Kosek, Dalibor; Durell, Stewart R.; Jenkins, Lisa M. Miller; Debnath, Subrata; Coussens, Nathan P.; Hall, Matthew D.; Appella, Daniel H.; Dyda, Fred; Mazur, Sharlyn J.; Appella, Ettore
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Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids
errJACS AU
IF8.7
err2023-06-29
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errZheng, Hongchao; Clausse, Victor; Amarasekara, Harsha; Mazur, Sharlyn J.; Botos, Istvan; Appella, Daniel H.
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Cyclopentane FIT-PNAs: bright RNA sensors (vol 57, pg 540, 2021)
err2023-01-01
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errTepper, Odelia; Zheng, Hongchao; Appella, Daniel H.; Yavin, Eylon
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Alkyl-substituted N-methylaryl-N′-aryl-4-aminobenzamides: A new series of small molecule inhibitors for Wip1 phosphatase
err2022-12-01
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errRobello, Marco; Zheng, Hongchao; Saha, Mrinmoy; Rosenker, Kara M. George; Debnath, Subrata; Kumar, Jay Prakash; Tagad, Harichandra D.; Mazur, Sharlyn J.; Appella, Ettore; Appella, Daniel H.
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Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently penetrate cells and inhibit microRNA-21
err2022-10-10
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errOAAI
errClausse, Victor; Zheng, Hongchao; Amarasekara, Harsha; Kruhlak, Michael; Appella, Daniel H.
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Cyclopentane peptide nucleic acid: Gold nanoparticle conjugates for the detection of nucleic acids in a microfluidic format环戊烷肽核酸: 用于以微流体形式检测核酸的金纳米颗粒缀合物
err2021-11-23
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errAmarasekara, Harsha; Oshaben, Kaylyn M.; Jeans, Kendra B.; Sangsari, Paniz Rezvan; Morgan, Nicole Y.; O'Farrell, Brian; Appella, Daniel H.
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Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA
err2021-01-06
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errZheng, Hongchao; Botos, Istvan; Clausse, Victor; Nikolayevskiy, Herman; Rastede, Elizabeth E.; Fouz, Munira F.; Mazur, Sharlyn J.; Appella, Daniel H.
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Cyclopentane FIT-PNAs: bright RNA sensors
err2021-01-01
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PREAI
errTepper, Odelia; Zheng, Hongchao; Appella, Daniel H.; Yavin, Eylon
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An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes
err2020-06-15
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errHait, Sabrina Helmold; Hogge, Christopher James; Rahman, Mohammad Arif; Ko, Eun-Ju; Hunegnaw, Ruth; Mushtaq, Zuena; Enyindah-Asonye, Gospel; Hoang, Tanya; Jenkins, Lisa M. Miller; Appella, Ettore; Appella, Daniel H.; Robert-Guroff, Marjorie
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Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens
err2019-11-01
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errClausse, Victor; Tao, Dingyin; Debnath, Subrata; Fang, Yuhong; Tagad, Harichandra D.; Wang, Yuhong; Sun, Hongmao; LeClair, Christopher A.; Mazur, Sharlyn J.; Lane, Kelly; Shi, Zhen-Dan; Vasalatiy, Olga; Eells, Rebecca; Baker, Lynn K.; Henderson, Mark J.; Webb, Martin R.; Shen, Min; Hall, Matthew D.; Appella, Ettore; Appella, Daniel H.; Coussens, Nathan P.
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The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target
err2019-09-01
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errNikolayevskiy, Herman; Robello, Marco; Scerba, Michael T.; Pasternak, Evan H.; Saha, Mrinmoy; Hartman, Tracy L.; Buchholz, Caitlin A.; Buckheit, Robert W., Jr.; Durell, Stewart R.; Appella, Daniel H.
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Allosteric modulation of β-cell M3 muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice
err2019-08-26
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errZhu, Lu; Rossi, Mario; Cohen, Amanda; Pham, Jonathan; Zheng, Hongchao; Dattaroy, Diptadip; Mukaibo, Taro; Melvin, James E.; Langel, Jennifer L.; Hattar, Samer; Matschinsky, Franz M.; Appella, Daniel H.; Doliba, Nicolai M.; Wess, Jurgen
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Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator
err2019-05-01
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errJenkins, Lisa M. Miller; Paine, Elliott L.; Deshmukh, Lalit; Nikolayevskiy, Herman; Lyons, Gaelyn C.; Scerba, Michael T.; Rosenker, Kara George; Luecke, Hans F.; Louis, John M.; Chertova, Elena; Gorelick, Robert J.; Ott, David E.; Clore, G. Marius; Appella, Daniel H.
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A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins
err2019-01-15
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errYang, Yu; Zhu, Jingyu; Hassink, Matthew; Jenkins, Lisa M. Miller; Wan, Yanmin; Appella, Daniel H.; Xu, Jianqing; Appella, Ettore; Zhang, Xiaoyan
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