Stewart R. Durell - Publications, H-index & Citations

Stewart R. Durell

National Cancer Institute

47H指数

126论文数

9.5K被引数

收录论文 37

发表时间

Angiopoietin-2 binds to FGFR2, inhibits FGF-FGFR2 signaling, and delays cutaneous wound healing by inhibiting wound angiogenesis Angiopoietin-2与FGFR2结合，抑制FGF-FGFR2信号通路，并通过抑制伤口血管生成而延缓皮肤伤口愈合。

Angiogenesis

IF9.2

2025-08-05

OAAI

Minji Sim; Hidetaka Ohnuki; Stewart Durell; Haydar Bulut; Yuyi Wang; Marzena Dyba; Sergey G. Tarasov; Lisa M. Jenkins; Giovanna Tosato

Conversion of Human Multidrug Transporter P-glycoprotein (ABCB1) from Drug Efflux to Uptake Pump: Evidence for a Switch Region Modulating the Direction of Substrate Transport 人类多药转运蛋白P-糖蛋白(ABCB1)从药物外排泵到摄取泵的转换：支持存在调控底物转运方向的转换区域的证据

JOURNAL OF MOLECULAR BIOLOGY

IF4.5

2025-04-01

PREAI

Sajid, Andaleeb; Ahmed, Shafaq; Ranganathan, Nandhini; Guha, Rajan; Murakami, Megumi; Durell, Stewart R.; Ambudkar, Suresh V.

Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-08-01

OAAI

Kumar, Jay Prakash; Kosek, Dalibor; Durell, Stewart R.; Jenkins, Lisa M. Miller; Debnath, Subrata; Coussens, Nathan P.; Hall, Matthew D.; Appella, Daniel H.; Dyda, Fred; Mazur, Sharlyn J.; Appella, Ettore

Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1)

DRUG RESISTANCE UPDATES

IF21.7

2023-11-01

OAAI

Murakami, Megumi; Sajid, Andaleeb; Lusvarghi, Sabrina; Durell, Stewart R.; Abel, Biebele; Vahedi, Shahrooz; Golin, John; Ambudkar, Suresh V.

The amyloid concentric β-barrel hypothesis: Models of amyloid beta 42 oligomers and annular protofibrils 淀粉样蛋白同心 β 桶假说: 淀粉样蛋白 β42低聚物和环状原纤维的模型

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2022-01-25

OAAI

Durell, Stewart R.; Kayed, Rakez; Guy, H. Robert

Altering the Double-Stranded DNA Specificity of the bZIP Domain of Zta with Site-Directed Mutagenesis at N182

ACS OMEGA

IF4.3

2021-12-28

OAAI

Ray, Sreejana; Tillo, Desiree; Assad, Nima; Ufot, Aniekanabasi; Porollo, Aleksey; Durell, Stewart R.; Vinson, Charles

The amyloid concentric β-barrel hypothesis: Models of synuclein oligomers, annular protofibrils, lipoproteins, and transmembrane channels 淀粉样蛋白同心 β 桶假说: 突触核蛋白寡聚体，环状原纤维，脂蛋白和跨膜通道的模型

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2021-10-11

OAAI

Durell, Stewart R.; Guy, H. Robert

Does the ATP-bound EQ mutant reflect the pre- or post-ATP hydrolysis state in the catalytic cycle of human P-glycoprotein (ABCB1)?

FEBS LETTERS

IF3

2021-02-28

OAAI

Lusvarghi, Sabrina; Durell, Stewart R.; Ambudkar, Suresh V.

REL Domain of NFATc2 Binding to Five Types of DNA Using Protein Binding Microarrays

ACS OMEGA

IF4.3

2021-02-02

OAAI

Ray, Sreejana; Tillo, Desiree; Durell, Stewart R.; Khund-Sayeed, Syed; Vinson, Charles

Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein 逆转人多药转运蛋白P-糖蛋白介导的药物转运方向

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-11-09

OAAI

Sajid, Andaleeb; Lusvarghi, Sabrina; Murakami, Megumi; Chufan, Eduardo E.; Abel, Biebele; Gottesman, Michael M.; Durell, Stewart R.; Ambudkar, Suresh, V

Activity-dependent isomerization of Kv4.2 by Pin1 regulates cognitive flexibility

NATURE COMMUNICATIONS

IF15.7

2020-03-26

OAAI

Hu, Jia-Hua; Malloy, Cole; Tabor, G. Travis; Gutzmann, Jakob J.; Liu, Ying; Abebe, Daniel; Karlsson, Rose-Marie; Durell, Stewart; Cameron, Heather A.; Hoffman, Dax A.

The structure-activity profile of mercaptobenzamides' anti-HIV activity suggests that thermodynamics of metabolism is more important than binding affinity to the target

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-09-01

OAAI

Nikolayevskiy, Herman; Robello, Marco; Scerba, Michael T.; Pasternak, Evan H.; Saha, Mrinmoy; Hartman, Tracy L.; Buchholz, Caitlin A.; Buckheit, Robert W., Jr.; Durell, Stewart R.; Appella, Daniel H.

Evidence for the Interaction of A3 Adenosine Receptor Agonists at the Drug-Binding Site(s) of Human P-glycoprotein (ABCB1)

MOLECULAR PHARMACOLOGY

IF3

2019-08-01

OAAI

Abel, Biebele; Tosh, Dilip K.; Durell, Stewart R.; Murakami, Megumi; Vahedi, Shahrooz; Jacobson, Kenneth A.; Ambudkar, Suresh, V

Resistance to Second-Generation HIV-1 Maturation Inhibitors

JOURNAL OF VIROLOGY

IF3.8

2019-03-15

OAAI

Urano, Emiko; Timilsina, Uddhav; Kaplan, Justin A.; Ablan, Sherimay; Ghimire, Dibya; Pham, Phuong; Kuruppu, Nishani; Mandt, Rebecca; Durell, Stewart R.; Nitz, Theodore J.; Martin, David E.; Wild, Carl T.; Gaur, Ritu; Freed, Eric O.

Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein

SCIENTIFIC REPORTS

IF3.9

2018-08-24

OAAI

Vahedi, Shahrooz; Lusvarghi, Sabrina; Pluchino, Kristen; Shafrir, Yinon; Durell, Stewart R.; Gottesman, Michael M.; Ambudkar, Suresh V.

A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-05-01

OAAI

Debnath, Subrata; Kosek, Dalibor; Tagad, Harichandra D.; Durell, Stewart R.; Appella, Daniel H.; Acevedo, Roderico; Grishaev, Alexander; Dyda, Fred; Appella, Ettore; Mazur, Sharlyn J.

Hydrophobic-hydrophilic forces in protein folding

BIOPOLYMERS

IF3.2

2017-06-21

OAAI

Durell, Stewart R.; Ben-Naim, Arieh

Probing Mercaptobenzamides as HIV Inactivators via Nucleocapsid Protein 7

CHEMMEDCHEM

IF3.4

2017-04-25

OAAI

Saha, Mrinmoy; Scerba, Michael T.; Shank, Nathaniel I.; Hartman, Tracy L.; Buchholz, Caitlin A.; Buckheit, Robert W., Jr.; Durell, Stewart R.; Appella, Daniel H.

Programmable Nanoscaffolds That Control Ligand Display to a G-Protein-Coupled Receptor in Membranes To Allow Dissection of Multivalent Effects

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2014-08-25

OAAI

Dix, Andrew V.; Moss, Steven M.; Phan, Khai; Hoppe, Travis; Paoletta, Silvia; Kozma, Eszter; Gao, Zhan-Guo; Durell, Stewart R.; Jacobson, Kenneth A.; Appella, Daniel H.

Chemical and structural flexibility contribute to the broad substrate and modulator specificity of multidrug resistance-linked P-glycoprotein (ABCB1).

CANCER RESEARCH

IF16.6

2013-04-01

PREAI

Ambudkar, Suresh V.; Chufan, Eduardo E.; Kapoor, Khyati; Durell, Stewart R.; Sim, Hong-May

研究方向