Howard Gamper - Publications, H-index & Citations

Howard Gamper

thomas jefferson university

36H指数

128论文数

5.1K被引数

收录论文 37

发表时间

Structure of ergosteryl-aspartate synthase reveals how an entrapped tRNA is used like a prosthetic swinging arm in the synthesis of aminoacylated sterols 麦角甾基-天冬氨酸合成酶的结构揭示了被困的tRNA如何在氨基酸酰化甾醇的合成中被用作类辅基摆动臂

Nature Communications

IF15.7

2026-05-28

OAAI

Hanako Murayama; Nathaniel Yakobov; Nassira Mahmoudi; Sasha Legrosdidier; Nicolas Fournier; Solène Zuttion; Kanata Matsumoto; Michihiro Nishimura; Jingwei Ji; Bruno Senger; Laurence Huck; Howard B. Gamper; Yoshiaki Kise; Ralph E. Kleiner; Mathieu Frechin; Ya-Ming Hou; Hubert D. Becker; Yuzuru Itoh; Frédéric Fischer; Osamu Nureki

An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting 一种RNA修饰可阻止扩展的密码子-反密码子相互作用促进+1移码。

Nature Communications

IF15.7

2025-08-11

OAAI

Evelyn M. Kimbrough; Ha An Nguyen; Haixing Li; Jacob M. Mattingly; Nevette A. Bailey; Wei Ning; Howard Gamper; Ya-Ming Hou; Ruben L. Gonzalez; Christine M. Dunham

Genome-wide profiling of tRNA modifications by Induro-tRNAseq reveals coordinated changes 全基因组范围tRNA修饰的Induro-tRNAseq分析揭示协同变化

NATURE COMMUNICATIONS

IF15.7

2025-01-26

OAAI

Nakano, Yuko; Gamper, Howard; Mcguigan, Henri; Maharjan, Sunita; Sun, Zhiyi; Yigit, Erbay; Gruenberg, Sebastian; Krishnan, Keerthana; Li, Nan-Sheng; Piccirilli, Joseph A.; Kleiner, Ralph; Nichols, Nicole; Gregory, Brian D.; Hou, Ya-Ming

Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology 线粒体tRNA的转录后甲基化差异有助于线粒体病理

NATURE COMMUNICATIONS

IF15.7

2024-10-18

OAAI

Maharjan, Sunita; Gamper, Howard; Yamaki, Yuka; Christian, Thomas; Henley, Robert Y.; Li, Nan-Sheng; Suzuki, Takeo; Suzuki, Tsutomu; Piccirilli, Joseph A.; Wanunu, Meni; Seifert, Erin; Wallace, Douglas C.; Hou, Ya-Ming

Nanopore signal deviations from pseudouridine modifications in RNA are sequence-specific: quantification requires dedicated synthetic controls

SCIENTIFIC REPORTS

IF3.9

2024-09-28

OAAI

Makhamreh, Amr; Tavakoli, Sepideh; Fallahi, Ali; Kang, Xinqi; Gamper, Howard; Nabizadehmashhadtoroghi, Mohammad; Jain, Miten; Hou, Ya-Ming; Rouhanifard, Sara H.; Wanunu, Meni

Unraveling RNA Conformation Dynamics in Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episode Syndrome with Solid-State Nanopores

ACS NANO

IF16

2024-06-21

PREAI

Namani, Srilahari; Kavetsky, Kyril; Lin, Chih-Yuan; Maharjan, Sunita; Gamper, Howard B.; Li, Nan-Sheng; Piccirilli, Joseph A.; Hou, Ya-Ming; Drndic, Marija

Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-05-22

OAAI

Li, Yunlong; Majumdar, Soneya; Treen, Ryan; Sharma, Manjuli R.; Corro, Jamie; Gamper, Howard B.; Manjari, Swati R.; Prusa, Jerome; Banavali, Nilesh K.; Stallings, Christina L.; Hou, Ya-Ming; Agrawal, Rajendra K.; Ojha, Anil K.

Strand bias in targeted gene repair is influenced by transcriptional activity (vol 22, pg 3852, 2002)

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Liu, L; Rice, MC; Drury, M; Cheng, SQ; Gamper, H; Kmiec, EB

Strand bias in targeted gene repair is influenced by transcriptional activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Liu, L; Rice, MC; Drury, M; Cheng, SQ; Gamper, H; Kmiec, EB

Semi-quantitative detection of pseudouridine modifications and type I/II hypermodifications in human mRNAs using direct long-read sequencing 使用直接长读测序半定量检测人mrna中的假尿苷修饰和I/II型超修饰

NATURE COMMUNICATIONS

IF15.7

2023-01-19

OAAI

Tavakoli, Sepideh; Nabizadeh, Mohammad; Makhamreh, Amr; Gamper, Howard; McCormick, Caroline A.; Rezapour, Neda K.; Hou, Ya-Ming; Wanunu, Meni; Rouhanifard, Sara H.

Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis

NATURE COMMUNICATIONS

IF15.7

2022-01-21

OAAI

Cui, Zhicheng; Li, Xiaojun; Shin, Joonyoung; Gamper, Howard; Hou, Ya-Ming; Sacchettini, James C.; Zhang, Junjie

Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP

NATURE COMMUNICATIONS

IF15.7

2021-12-13

OAAI

Carbone, Christine E.; Loveland, Anna B.; Gamper, Howard B., Jr.; Hou, Ya-Ming; Demo, Gabriel; Korostelev, Andrei A.

Twice exploration of tRNA+1 frameshifting in an elongation cycle of protein synthesis

NUCLEIC ACIDS RESEARCH

IF13.1

2021-08-20

OAAI

Gamper, Howard; Mao, Yujia; Masuda, Isao; McGuigan, Henri; Blaha, Gregor; Wang, Yuhong; Xu, Shoujun; Hou, Ya-Ming

Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression

ELIFE

IF0

2021-08-12

OAAI

Masuda, Isao; Hwang, Jae-Yeon; Christian, Thomas; Maharjan, Sunita; Mohammad, Fuad; Gamper, Howard; Buskirk, Allen R.; Hou, Ya-Ming

Structural basis for+1 ribosomal frameshifting during EF-G-catalyzed translocation

NATURE COMMUNICATIONS

IF15.7

2021-07-30

OAAI

Demo, Gabriel; Gamper, Howard B.; Loveland, Anna B.; Masuda, Isao; Carbone, Christine E.; Svidritskiy, Egor; Hou, Ya-Ming; Korostelev, Andrei A.

Insights into genome recoding from the mechanism of a classic+1-frameshifting tRNA

NATURE COMMUNICATIONS

IF15.7

2021-01-12

OAAI

Gamper, Howard; Li, Haixing; Masuda, Isao; Robkis, D. Miklos; Christian, Thomas; Conn, Adam B.; Blaha, Gregor; Petersson, E. James; Gonzalez, Ruben L.; Hou, Ya-Ming

tRNAArg-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation

CELL CHEMICAL BIOLOGY

IF7.2

2020-07-01

OAAI

Avcilar-Kucukgoze, Irem; Gamper, Howard; Polte, Christine; Ignatova, Zoya; Kraetzner, Ralph; Shtutman, Michael; Hou, Ya-Ming; Dong, Dawei W.; Kashina, Anna

tRNA 3′-amino-tailing for stable amino acid attachment

RNA

IF5

2018-09-14

OAAI

Gamper, Howard; Hou, Ya-Ming

Selective terminal methylation of a tRNA wobble base

NUCLEIC ACIDS RESEARCH

IF13.1

2018-01-18

OAAI

Masuda, Isao; Takase, Ryuichi; Matsubara, Ryuma; Paulines, Mellie June; Gamper, Howard; Limbach, Patrick A.; Hou, Ya-Ming

Transcription-translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits

NUCLEIC ACIDS RESEARCH

IF13.1

2017-08-16

OAAI

Fan, Haitian; Conn, Adam B.; Williams, Preston B.; Diggs, Stephen; Hahm, Joseph; Gamper, Howard B., Jr.; Hou, Ya-Ming; O'Leary, Sean E.; Wang, Yinsheng; Blaha, Gregor M.

研究方向