Smita S. Patel - Publications, H-index & Citations

Smita S. Patel

Rutgers University

71H指数

346论文数

1.8W被引数

收录论文 141

发表时间

Torsion is a dynamic regulator of DNA replication stalling and reactivation 扭转是DNA复制停滞和再激活的动态调节因子。

Nature Communications

IF15.7

2025-11-26

OAAI

Xiaomeng Jia; Xiang Gao; Shuming Zhang; James T. Inman; Yifeng Hong; Anupam Singh; Fahad Rashid; James M. Berger; Smita S. Patel; Michelle D. Wang

Human mitochondrial RNA polymerase structures reveal transcription start site and slippage mechanism 人线粒体RNA聚合酶结构揭示了转录起始位点和滑移机制

Molecular Cell

IF16.6

2025-07-24

PREAI

Jiayu Shen; Quinten Goovaerts; Yogeeshwar Ajjugal; Brent De Wijngaert; Kalyan Das; Smita S. Patel

Sequence-specific dynamic DNA bending explains mitochondrial TFAM's dual role in DNA packaging and transcription initiation

NATURE COMMUNICATIONS

IF15.7

2024-06-27

OAAI

Huh, Hyun; Shen, Jiayu; Ajjugal, Yogeeshwar; Ramachandran, Aparna; Patel, Smita S.; Lee, Sang-Hyuk

Unraveling blunt-end RNA binding and ATPase-driven translocation activities of the RIG-I family helicase LGP2

NUCLEIC ACIDS RESEARCH

IF13.1

2023-11-28

OAAI

Lee, Kuan-Ying; Craig, Candice; Patel, Smita S.

Twinkle-Catalyzed Toehold-Mediated DNA Strand Displacement Reaction

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-11-02

PREAI

Singh, Anupam; Patel, Gayatri; Patel, Smita S.

Refining Risk for Alzheimer's Disease Among Heterozygous APOE ε4 Carriers 细化杂合apoeε4携带者患阿尔茨海默病的风险

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2023-07-18

PREAI

Patel, Smita; Wei, Jun; Shi, Zhuqing; Rifkin, Andrew S.; Zheng, S. Lilly; Gelfman, Elizabeth; Duggan, David; Helfand, Brian T.; Hulick, Peter J.; Xu, Jianfeng

RIG-I recognizes metabolite-capped RNAs as signaling ligands

NUCLEIC ACIDS RESEARCH

IF13.1

2023-06-16

OAAI

Schweibenz, Brandon D.; Solotchi, Mihai; Hanpude, Pranita; Devarkar, Swapnil C.; Patel, Smita S.

The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase γ

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-01

OAAI

Johnson, Laura C.; Singh, Anupam; Patel, Smita S.

The N-terminal Domain of Twinkle, the Replicative Helicase in Human Mitochondria, Binds DNA and is Essential in Supporting Processive DNA Synthesis by the Mitochondrial DNA Polymerase

FASEB JOURNAL

IF4.2

2022-05-13

PREAI

Johnson, Laura C.; Singh, Anupam; Patel, Smita

The intrinsically disordered CARDs-Helicase linker in RIG-I is a molecular gate for RNA proofreading

EMBO JOURNAL

IF8.3

2022-04-19

OAAI

Schweibenz, Brandon D.; Devarkar, Swapnil C.; Solotchi, Mihai; Craig, Candice; Zheng, Jie; Pascal, Bruce D.; Gokhale, Samantha; Xie, Ping; Griffin, Patrick R.; Patel, Smita S.

Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase

MOLECULAR CELL

IF16.6

2021-01-01

OAAI

De Wijngaert, Brent; Sultana, Shemaila; Singh, Anupam; Dharia, Chhaya; Vanbuel, Hans; Shen, Jiayu; Vasilchuk, Daniel; Martinez, Sergio E.; Kandiah, Eaazhisai; Patel, Smita S.; Das, Kalyan

Structure, mechanism, and regulation of mitochondrial DNA transcription initiation 线粒体DNA转录起始的结构、机制和调控

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-01

OAAI

Basu, Urmimala; Bostwick, Alicia M.; Das, Kalyan; Dittenhafer-Reed, Kristin E.; Patel, Smita S.

The dynamic landscape of transcription initiation in yeast mitochondria

NATURE COMMUNICATIONS

IF15.7

2020-08-27

OAAI

Sohn, Byeong-Kwon; Basu, Urmimala; Lee, Seung-Won; Cho, Hayoon; Shen, Jiayu; Deshpande, Aishwarya; Johnson, Laura C.; Das, Kalyan; Patel, Smita S.; Kim, Hajin

The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-05-01

OAAI

Basu, Urmimala; Mishra, Nandini; Farooqui, Mohammed; Shen, Jiayu; Johnson, Laura C.; Patel, Smita S.

Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles 复制障碍解释了DNA合成过程中正确核苷酸的过度切除

EMBO JOURNAL

IF8.3

2020-02-09

OAAI

Singh, Anupam; Pandey, Manjula; Nandakumar, Divya; Raney, Kevin D.; Yin, Y. Whitney; Patel, Smita S.

The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation

NUCLEIC ACIDS RESEARCH

IF13.1

2020-01-25

OAAI

Basu, Urmimala; Lee, Seung-Won; Deshpande, Aishwarya; Shen, Jiayu; Sohn, Byeong-Kwon; Cho, Hayoon; Kim, Hajin; Patel, Smita S.

Time-resolved analysis of transcription through chromatin

METHODS

IF4.3

2019-04-01

OAAI

Chang, Han-Wen; Hsieh, Fu-Kai; Patel, Smita S.; Studitsky, Vasily M.

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

NATURE COMMUNICATIONS

IF15.7

2018-12-18

OAAI

Zheng, Jie; Wang, Chen; Chang, Mi Ra; Devarkar, Swapnil C.; Schweibenz, Brandon; Crynen, Gogce C.; Garcia-Ordonez, Ruben D.; Pascal, Bruce D.; Novick, Scott J.; Patel, Smita S.; Marcotrigiano, Joseph; Griffin, Patrick R.

Highly efficient 5′ capping of mitochondrial RNA with NAD+ and NADH by yeast and human mitochondrial RNA polymerase

ELIFE

IF0

2018-12-12

OAAI

Bird, Jeremy G.; Basu, Urmimala; Kuster, David; Ramachandran, Aparna; Grudzien-Nogalska, Ewa; Towheed, Atif; Wallace, Douglas C.; Kiledjian, Megerditch; Temiakov, Dmitry; Patel, Smita S.; Ebright, Richard H.; Nickels, Bryce E.

RIG-I Uses an ATPase-Powered Translocation-Throttling Mechanism for Kinetic Proofreading of RNAs and Oligomerization

MOLECULAR CELL

IF16.6

2018-10-01

OAAI

Devarkar, Swapnil C.; Schweibenz, Brandon; Wang, Chen; Marcotrigiano, Joseph; Patel, Smita S.

研究方向