未登录

T

Timothy C. Humphrey

University of Oxford

H指数:25

被引数:2,297

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Transcription termination counteracts DNA damage after WEE1 inhibition

WEE1抑制后转录终止对抗DNA损伤

Nucleic Acids Research

IF13.1

2026-02-100

PRE

Prime Editing of ATRX point mutations in glioblastoma reveals lethal dependencies and targetable vulnerabilities

ATRX基因点突变的体细胞编辑揭示了致命依赖性及可靶向的脆弱性

IF13.4

2025-11-010

OAAI

Elevated reactive oxygen species can drive the alternative lengthening of telomeres pathway in ATRX-null cancers

升高的活性氧可以驱动ATRX-null癌症中的端粒替代性延长途径。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-02-081

OA

Isoform Switching Regulates the Response to Ionizing Radiation Through SRSF1

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

IF6.5

2024-08-010

OAAI

A National audit of the care of patients with acute kidney injury in England and Wales in 2019 and the association with patient outcomes

CLINICAL MEDICINE

IF3.9

2024-03-010

OAAI

A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation

IF3.4

2023-08-014

OAAI

Break-induced loss of heterozygosity in fission yeast:: Dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2727

OAAI

Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast

NUCLEIC ACIDS RESEARCH

IF13.1

2023-03-231

OAAI

Ionizing Radiation Drives Key Regulators of Antigen Presentation and a Global Expansion of the Immunopeptidome

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2022-11-0111

OAAI

The role of histone H3K36me3 writers, readers and erasers in maintaining genome stability

组蛋白H3K36me3写入器、读码器和橡皮擦在维持基因组稳定性中的作用

IF2.7

2022-11-0116

OAAI

Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication

IF3.7

2021-07-069

OAAI

The Challenge of Combining Chemo- and Radiotherapy with Checkpoint Kinase Inhibitors

CLINICAL CANCER RESEARCH

IF10.2

2021-02-1516

OAAI

Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks

NUCLEIC ACIDS RESEARCH

IF13.1

2019-12-1210

OAAI

Misrepair in Context: TGFβ Regulation of DNA Repair

FRONTIERS IN ONCOLOGY

IF3.3

2019-08-2732

OAAI

An essential role for dNTP homeostasis following CDK-induced replication stress

JOURNAL OF CELL SCIENCE

IF3.6

2019-03-2515

OAAI

Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity

NUCLEIC ACIDS RESEARCH

IF13.1

2018-07-0914

OAAI

Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription

IF6.9

2017-09-0124

OAAI

MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-07-0334

OAAI

A role for human homologous recombination factors in suppressing microhomology-mediated end joining

人类同源重组因子在抑制微同源介导的末端连接中的作用

NUCLEIC ACIDS RESEARCH

IF13.1

2016-04-2985

OAAI

WEE1 inhibition selectively kills histone H3K36me3-deficient cancers by dNTP starvation

CANCER RESEARCH

IF16.6

2016-01-140

PRE