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The Polybrominated Diphenyl Ether Bromoxib Disrupts Nuclear Import and Export by Affecting Nucleoporins of the Nuclear Pore Complex 多溴联苯醚溴oxib通过影响核孔复合体的核孔蛋白来破坏核输入和输出。 Krings, Karina S.; Ritchie, Anastasia; Schmitt, Laura; Hatzfeld, Judith; Totzke, Gudrun; Lenz, Thomas; Mendiburo, Maria Jose; Stork, Bjoern; Teusch, Nicole; Proksch, Peter; Stuehler, Kai; Mueller, Lisa; Wesselborg, Sebastian 分享 收藏
Novel 4-alkoxy Meriolin Congeners Potently Induce Apoptosis in Leukemia and Lymphoma Cells Krings, Karina S.; Wassenberg, Tobias R.; Cea-Medina, Pablo; Schmitt, Laura; Lechtenberg, Ilka; Llewellyn, Tanya R.; Qin, Nan; Gohlke, Holger; Wesselborg, Sebastian; Mueller, Thomas J. J. 分享 收藏
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Targeting mitochondrial metabolism by the mitotoxin bromoxib in leukemia and lymphoma cells Schmitt, Laura; Krings, Karina S.; Wolsing, Andre; Buque, Xabier; Zimmermann, Marcel; Flores-Romero, Hector; Lenz, Thomas; Lechtenberg, Ilka; Peter, Christoph; Stork, Bjoern; Teusch, Nicole; Proksch, Peter; Stuehler, Kai; Garcia-Saez, Ana J.; Reichert, Andreas S.; Aspichueta, Patricia; Bhatia, Sanil; Wesselborg, Sebastian 分享 收藏
Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cells 抗肿瘤治疗影响健康人骨髓间充质干细胞的体外表型和功能 Scherer, Bo; Bogun, Lucienne; Koch, Annemarie; Jaeger, Paul; Maus, Uwe; Schmitt, Laura; Krings, Karina S.; Wesselborg, Sebastian; Haas, Rainer; Schroeder, Thomas; Geyh, Stefanie 分享 收藏
Novel meriolin derivatives potently inhibit cell cycle progression and transcription in leukemia and lymphoma cells via inhibition of cyclin-dependent kinases (CDKs) Schmitt, Laura; Hoppe, Julia; Cea-Medina, Pablo; Bruch, Peter-Martin; Krings, Karina S.; Lechtenberg, Ilka; Driessen, Daniel; Peter, Christoph; Bhatia, Sanil; Dietrich, Sascha; Stork, Bjoern; Fritz, Gerhard; Gohlke, Holger; Mueller, Thomas J. J.; Wesselborg, Sebastian 分享 收藏
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Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2 Schmitt, Laura; Lechtenberg, Ilka; Driessen, Daniel; Flores-Romero, Hector; Skowron, Margaretha A.; Sekeres, Marlena; Hoppe, Julia; Krings, Karina S.; Llewellyn, Tanya R.; Peter, Christoph; Stork, Bjorn; Qin, Nan; Bhatia, Sanil; Nettersheim, Daniel; Fritz, Gerhard; Garcia-Saez, Ana J.; Mueller, Thomas J. J.; Wesselborg, Sebastian 分享 收藏
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Cardiac injection of USSC boosts remuscularization of the infarcted heart by shaping the T-cell response Ding, Zhaoping; Tan, Kezhe; Alter, Christina; Temme, Sebastian; Bouvain, Pascal; Owenier, Christoph; Haensch, Sebastian; Wesselborg, Sebastian; Peter, Christoph; Weidtkamp-Peters, Stefanie; Floegel, Ulrich; Schira-Heinen, Jessica; Stuehler, Kai; Hesse, Julia; Koegler, Gesine; Schrader, Juergen 分享 收藏
The mycotoxin viriditoxin induces leukemia- and lymphoma-specific apoptosis by targeting mitochondrial metabolism 霉菌毒素病毒毒素通过靶向线粒体代谢诱导白血病和淋巴瘤特异性细胞凋亡 Stuhldreier, Fabian; Schmitt, Laura; Lenz, Thomas; Hinxlage, Ilka; Zimmermann, Marcel; Wollnitzke, Philipp; Schliehe-Diecks, Julian; Liu, Yang; Jaeger, Paul; Geyh, Stefanie; Teusch, Nicole; Peter, Christoph; Bhatia, Sanil; Haas, Rainer; Levkau, Bodo; Reichert, Andreas S.; Stuehler, Kai; Proksch, Peter; Stork, Bjoern; Wesselborg, Sebastian 分享 收藏
Heterologously secreted MbxA from Moraxella bovis induces a membrane blebbing response of the human host cell Erenburg, Isabelle N.; Haensch, Sebastian; Chacko, Feby M.; Hamacher, Anna; Wintgens, Sebastian; Stuhldreier, Fabian; Poschmann, Gereon; Spitz, Olivia; Stuehler, Kai; Wesselborg, Sebastian; Hegemann, Johannes; Smits, Sander H. J.; Weidtkamp-Peters, Stefanie; Schmitt, Lutz 分享 收藏
Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells Fin56-induced铁死亡由自噬介导的GPX4降解支持，并与mTOR抑制协同作用杀死膀胱癌细胞 Sun, Yadong; Berleth, Niklas; Wu, Wenxian; Schluetermann, David; Deitersen, Jana; Stuhldreier, Fabian; Berning, Lena; Friedrich, Annabelle; Akguen, Seda; Mendiburo, Maria Jose; Wesselborg, Sebastian; Conrad, Marcus; Berndt, Carsten; Stork, Bjorn 分享 收藏
An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis Schmitz, Katharina; Cox, Jan; Esser, Lea Marie; Voss, Martin; Sander, Katja; Loeffler, Antje; Hillebrand, Frank; Erkelenz, Steffen; Schaal, Heiner; Kaehne, Thilo; Klinker, Stefan; Zhang, Tao; Nagel-Steger, Luitgard; Willbold, Dieter; Seggewiss, Sabine; Schluetermann, David; Stork, Bjoern; Grimmler, Matthias; Wesselborg, Sebastian; Peter, Christoph 分享 收藏
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Induction of New Lactam Derivatives From the Endophytic Fungus Aplosporella javeedii Through an OSMAC Approach Gao, Ying; Stuhldreier, Fabian; Schmitt, Laura; Wesselborg, Sebastian; Guo, Zhiyong; Zou, Kun; Mandi, Attila; Kurtan, Tibor; Liu, Zhen; Proksch, Peter 分享 收藏
First Results from a Screening of 300 Naturally Occurring Compounds: 4,6-dibromo-2-(2′,4′-dibromophenoxy)phenol, 4,5,6-tribromo-2-(2′,4′-dibromophenoxy)phenol, and 5-epi-nakijinone Q as Substances with the Potential for Anticancer Therapy Mayer, Saskia; Prechtl, Marie; Liebfried, Pia; Cadeddu, Ron-Patrick; Stuhldreier, Fabian; Kohl, Matthias; Wenzel, Folker; Stork, Bjoern; Wesselborg, Sebastian; Proksch, Peter; Germing, Ulrich; Haas, Rainer; Jaeger, Paul 分享 收藏
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