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A

Ahmed A. Al‐Karmalawy

horus university

51H指数
232论文数
7.2K被引数
收录论文 126
发表时间
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Covalent Molecular Glues: Mechanisms, Design Principles, and Emerging Therapeutic Opportunities in Targeted Protein Degradation共价分子胶：靶向蛋白降解中的机制、设计原则及新兴治疗机遇
errArchiv der Pharmazie
IF3.6
err2026-05-22
err0
PREAI
errAhmed A. Al-Karmalawy; Mohamed Ibrahim Attia; Tarek A. Yousef; Mohammed Bashar Al-Qazzan; Mohammed Al-Akeedi; Arwa Omar Al Khatib; Samia S. Hawas
err分享
err收藏
Discovery of Caralluma-derived pregnane glycosides as potent and selective cholinesterase inhibitors: integrated in silico and in vitro evaluation从卡勒鲁玛属植物中发现的孕甾烷糖苷作为强效且选择性胆碱酯酶抑制剂的发现：整合体外与计算机模拟评价
errrsc adv.
IF0
err2026-05-15
err0
errOAAI
errAhmed A. Al-Karmalawy; Mohamed Ibrahim Attia; Radwan Alnajjar; Riham A. El-Shiekh; Arwa Omar Al Khatib; Tarek A. Yousef; Essam Abdel-Sattar
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Designing Telomerase Inhibitors for Cancer Therapy: Mechanistic Insights, Medicinal Chemistry Strategies, Challenges, and Future Directions设计用于癌症治疗的端粒酶抑制剂：机制见解、药物化学策略、挑战和未来方向
errArchiv der Pharmazie
IF3.6
err2026-05-12
err0
PREAI
errAhmed A. Al-Karmalawy; Mohamed Ibrahim Attia; Marwa Sharaky; Arwa Omar Al Khatib; Tarek A. Yousef; Samia S. Hawas
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Designing the Next Generation of Antibiotics: Structure, SAR, and Strategy in Medicinal Chemistry (2000-2025)设计下一代抗生素：药物化学中的结构、构效关系与策略（2000-2025）
errMedicinal Research Reviews
IF11.6
err2026-05-01
err0
PREAI
errAl-Karmalawy, Ahmed A.; Al-Dakhil, Abdullah; Ashour, Nada A.; Yousef, Tarek A.; Mabrouk, Samar S.; Al Khatib, Arwa Omar; Hawas, Samia S.
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Integrated metabolite profiling and molecular docking reveal anti-aging potential of Clerodendrum infortunatum L. fractions整合代谢物组学和分子对接揭示Clerodendrum infortunatum L. 分离物的抗衰老潜力
errScientific Reports
IF3.9
err2026-04-22
err0
errOAAI
errFatma Atef; Mostafa A. Abdelkawy; Basma M. Eltanany; Laura Pont; Ahmed A. Al-Karmalawy; Fernando Benavente; Inas Y. Younis; Asmaa M. Otify
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Antiviral activity and chemical characterization of Egyptian Ziziphus spina-christi against human respiratory viruses抗病毒活性和化学表征：埃及Ziziphus spina-christi对人类呼吸道病毒的作用
errScientific Reports
IF3.9
err2026-04-19
err0
errOAAI
errAmany Elkhrsawy; Omnia Kutkat; Yassmin Moatasim; Mohamed S. Refaey; Ahmed A. Al-Karmalawy; Eman Elabd; Amr Keshta; Kamal Shaltout; Rabeh El-Shesheny
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Hybrid benzylidene thiazolidine-2; 4-diones as potent apoptosis-inducing anticancer agents: design-driven optimization; cytotoxic profiling; and mechanistic validation in prostate cancer杂化肉苄基噻唑烷二酮类作为强效诱导凋亡的抗肿瘤剂：设计驱动优化、细胞毒性表征及在前列腺癌中的机制验证
errrsc adv.
IF0
err2026-04-17
err0
errOAAI
errSaad Shaaban †; Samia S. Hawas †; Marwa Sharaky; Hussein Ba-Ghazal; Ayman Abo Elmaaty; Khadra B. Alomari; Mohamed Alaasar; Asma M. Elsharif; Fatema S. Alatawi; Mohamed Alaa Mohamed; Arwa Omar Al Khatib; Ahmed A. Al-Karmalawy
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Targeting the Menin–KMT2A Interface: Medicinal Chemistry Rules Governing Reversible, Covalent, and Degrader Inhibitors靶向Menin–KMT2A界面：可逆性、共价性和降解剂抑制剂相关的药物化学规则
errChemical Biology & Drug Design
IF3.3
err2026-04-04
err0
PREAI
errAhmed A. Al-Karmalawy; Mohamed E. Eissa; Tarek A. Yousef; Marwa Sharaky; Arwa Omar Al Khatib; Samia S. Hawas
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PTC-Assisted Chemoselective S-Alkylation of 5-Mercapto-1,3,4-Oxadiazol Derivative: Multi-Target Anticancer via EGFR, Telomerase, and Thymidylate Synthase Inhibition With Apoptosis Induction相转移催化剂辅助的5-巯基-1,3,4-噁二唑衍生物的选择性S-烷基化：通过抑制EGFR、端粒酶和胸苷酸合酶实现多靶点抗癌作用并诱导凋亡
errDrug Development Research
IF4.2
err2026-03-29
err0
PREAI
errZakaria, Asmaa; Al-Karmalawy, Ahmed A.; Hawas, Samia S.; Ali, Ali Khalil; Elsayed, Galal A.; Al Khatib, Arwa Omar; Abbass, Eslam M.
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Synthesis, characterization, molecular modelling, and antimicrobial evaluation of novel drug–polymer composites grafted with polyvinylpyrrolidone新型药物-聚合物复合材料接枝聚乙烯吡咯烷酮的合成、表征、分子建模及抗菌活性评价
errJournal of Molecular Structure
IF4.7
err2026-03-03
err0
PREAI
errZahraa Mokhtar; Mohamed E. Eissa; Mohammed Bashar Al-Qazzan; Violet Kasabri; Mohammed Al-Akeedi; Sana Hitur Awad; Tarek A. Yousef; Ahmed A. Al-Karmalawy
err分享
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Targeting cell cycle and apoptotic pathways with newly synthesized diselenide-linked imidazolone analogues with strong CDK6-targeting potential
errrsc adv.
IF0
err2026-02-05
err0
errOAAI
errMarwa Abdel-Motaal †; Saad Shaaban †; Samia S. Hawas †; Asma M. Elsharif; Marwa Sharaky; Fatema S. Alatawi; Mohamed E. Eissa; Arwa Omar Al Khatib; Hany M. Abd El-Lateef; Medhat Asem; Ahmed A. Al-Karmalawy
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Organoselenium-based Schiff bases and amidic acid derivatives as promising anticancer agents targeting breast cancer by downregulating BCL-2: design; synthesis; and biological evaluation
errrsc adv.
IF0
err2026-02-02
err0
errOAAI
errSaad Shaaban; Samia S. Hawas; Asma M. Elsharif; Marwa Sharaky; Hussein Ba-Ghazal; Mohamed Alaasar; Fatema S. Alatawi; Khadra B. Alomari; Mohamed E. Eissa; Arwa Omar Al Khatib; Radwan Alnajjar; Ahmed A. Al-Karmalawy
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Bridging mechanism and design: modern medicinal chemistry approaches to thymidylate synthase inhibitors桥接机制和设计: 胸苷酸合酶抑制剂的现代药物化学方法
errrsc adv.
IF0
err2026-01-30
err0
errOAAI
errAhmed A. Al-Karmalawy; Mohamed E. Eissa; Tarek A. Yousef; Arwa Omar Al Khatib; Samia S. Hawas
err分享
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Editorial Expression of Concern: Bioactive fraction from Plumeria obtusa L. attenuates LPS‑induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF‑MS and molecular docking编者按：Plumeria obtusa L.的生物活性组分减轻LPS诱导的小鼠急性肺损伤和在RAW 264.7巨噬细胞中的炎症：LC/QToF-MS与分子对接
errInflammopharmacology
IF5.3
err2025-12-03
err0
errOAAI
errYousra T. Eloutify; Riham A. El‑Shiekh; Khaled Meselhy Ibrahim; Ahmed R. Hamed; Ahmed A. Al‑Karmalawy; Aya A. Shokry; Yasmine H. Ahmed; Bharathi Avula; Kumar Katragunta; Ikhlas A. Khan; Meselhy R. Meselhy
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Multi-target design of fused cyclic pyrimidine-2-thione candidates as DNA intercalators and topoisomerase I/II inhibitors融合型环状嘧啶-2-硫酮候选物的多靶点设计作为DNA嵌入剂和拓扑异构酶I/II抑制剂
errFuture Medicinal Chemistry
IF3.4
err2025-12-01
err0
PREAI
errKhalil, Mahmoud S.; Al-Karmalawy, Ahmed A.; Abo Elmaaty, Ayman; Elsayed, Galal A.; Hassan, A. M. A.
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Exploring the apoptosis-inducing potential of Syzygium cimini leaves in cancer treatment; LC-ESI-MS/MS analysis, biological assessments, and computational studies探究Syzygium cimini叶片在癌症治疗中的促凋亡潜力；LC-ESI-MS/MS分析、生物学评估和计算研究
errScientific African
IF3.3
err2025-11-24
err0
errOAAI
errAhmed A. Al-Karmalawy; Mohamed E. Eissa; Rehab F. Taher; Tarek A. Yousef; Arwa Omar Al Khatib; Marwa Sharaky; Radwan Alnajjar; Haidy A. Abbas
err分享
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Leveraging the Fragment Merging Approach for Synthetizing Novel Selanyl Phenyl Acetamide Thiazolidinedione Hybrids Endowed With Apoptotic Potential for Cancer Treatment利用片段融合方法合成具有抗癌凋亡潜力的新型硒基苯基乙酰胺噻唑烷二酮杂化物
errDrug Development Research
IF4.2
err2025-11-17
err0
PREAI
errSaad Shaaban; Ayman Abo Elmaaty; Aya Yaseen Mahmood Alabdali; Hussein Ba-Ghazal; Marwa Sharaky; Mohamed Alaa Mohamed; Mai A. E. Mourad; Mohamed Alaasar; Fatema Suliman Alatawi; Tarek A. Yousef; Arwa Omar Al Khatib; Ahmed A. Al-Karmalawy
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Design and development of potent roflumilast analogues targeting PDE-4B: selectivity and pharmacokinetic insights靶向PDE-4B的高效罗氟司特类似物的设计与开发：选择性及药代动力学见解
errBioorganic Chemistry
IF4.7
err2025-11-04
err0
PREAI
errAhmed M. Moussa; Heba Abdelrasheed Allam; Ahmed A. Al-Karmalawy; Abdelrahman K. Salem; Radwan Alnajjar; Sally T. Mahmoud; Marwa A. Fouad; Mohamed K. El-Ashrey
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Design; synthesis; and anticancer evaluation of novel pyrazole–thiophene hybrid derivatives as multitarget inhibitors of wild EGFR; mutant (T790M) EGFR; and VEGFR-2设计、合成及对新型吡唑-噻吩杂合衍生物作为野生型EGFR、突变型(T790M)EGFR和VEGFR-2多靶点抑制剂的抗癌活性评价
errRSC Adv.
IF0
err2025-10-22
err0
errOAAI
errMohammed N. Sallam †; Ahmed A. Al-Karmalawy †; Eslam M. Abbass; Samia S. Hawas; Abeer M. El-Naggar; A. M. A. Hassan
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Comprehensive phytochemical mapping and biomedical evaluation of Lawsonia inermis L: a potential natural treatment for diabetic foot ulcers with wound healing and antimicrobial effects综合植物化学成分分析与生物医学评价： Lawsonia inermis L 作为一种具有创面愈合和抗菌作用的糖尿病足溃疡潜在天然治疗方法
errFitoterapia
IF2.6
err2025-10-17
err0
PREAI
errSafaa M. Kotb; Mai M. Farid; Ahmed A. Al-Karmalawy; Magdy A.H. Zahran; Briksam S. Mohamed; Abdelnaser A. Gadallah; Bishoy El-Aarag
err分享
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研究方向

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D
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