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Disruption of polyunsaturated fatty acid biosynthesis drives and death Kanefsky, Joice; Basse, Mary; Sokei, Judith; di Martino, Orsola; Valin, Liana; Jaspers, Yorrick; Martinez, Esteban; Huhn, Jacklyn; Di Marcantonio, Daniela; Magee, Jeffrey A.; Goldman, Aaron R.; Tang, Hsin-Yao; Ferraro, Francesca; Kemp, Stephan; Wiest, David L.; Sykes, Stephen M. 分享 收藏
Quantitative, titratable and high-throughput reporter assays to measure DNA double strand break repair activity in cells Rajendra, Eeson; Grande, Diego; Mason, Bethany; Di Marcantonio, Daniela; Armstrong, Lucy; Hewitt, Graeme; Elinati, Elias; Galbiati, Alessandro; Boulton, Simon J.; Heald, Robert A.; Smith, Graeme C. M.; Robinson, Helen M. R. 分享 收藏
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors TET2和DNMT3A突变对DNA修复和白血病细胞对PARP抑制剂的敏感性产生不同的影响 Maifrede, Silvia; Le, Bac Viet; Nieborowska-Skorska, Margaret; Golovine, Konstantin; Sullivan-Reed, Katherine; Dunuwille, Wangisa M. B.; Nacson, Joseph; Hulse, Michael; Keith, Kelsey; Madzo, Jozef; Caruso, Lisa Beatrice; Gazze, Zachary; Lian, Zhaorui; Padella, Antonella; Chitrala, Kumaraswamy N.; Bartholdy, Boris A.; Matlawska-Wasowska, Ksenia; Di Marcantonio, Daniela; Simonetti, Giorgia; Greiner, Georg; Sykes, Stephen M.; Valent, Peter; Paietta, Elisabeth M.; Tallman, Martin S.; Fernandez, Hugo F.; Litzow, Mark R.; Minden, Mark D.; Huang, Jian; Martinelli, Giovanni; Vassiliou, George S.; Tempera, Italo; Piwocka, Katarzyna; Johnson, Neil; Challen, Grant A.; Skorski, Tomasz 分享 收藏
ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia Di Marcantonio, Daniela; Martinez, Esteban; Kanefsky, Joice S.; Huhn, Jacklyn M.; Gabbasov, Rashid; Gupta, Anushk; Krais, John J.; Peri, Suraj; Tan, YinFei; Skorski, Tomasz; Dorrance, Adrienne; Garzon, Ramiro; Goldman, Aaron R.; Tang, Hsin-Yao; Johnson, Neil; Sykes, Stephen M. 分享 收藏
The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22 Stanek, Timothy J.; Gennaro, Victoria J.; Tracewell, Mason A.; Di Marcantonio, Daniela; Pauley, Kristen L.; Butt, Sabrina; McNair, Christopher; Wang, Feng; Kossenkov, Andrew, V; Knudsen, Karen E.; Butt, Tauseef; Sykes, Stephen M.; McMahon, Steven B. 分享 收藏
BRCA1 Mutational Complementation Induces Synthetic Viability Nacson, Joseph; Di Marcantonio, Daniela; Wang, Yifan; Bernhardy, Andrea J.; Clausen, Emma; Hua, Xiang; Cai, Kathy Q.; Martinez, Esteban; Feng, Wanjuan; Callen, Elsa; Wu, Wei; Gupta, Gaorav P.; Testa, Joseph R.; Nussenzweig, Andre; Sykes, Stephen M.; Johnsons, Neil 分享 收藏
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance (vol 24, 3513, 2018) Nacson, Joseph; Krais, John J.; Bernhardy, Andrea J.; Clausen, Emma; Feng, Wanjuan; Wang, Yifan; Nicolas, Emmanuelle; Cai, Kathy Q.; Tricarico, Rossella; Hua, Xiang; DiMarcantonio, Daniela; Martinez, Esteban; Zong, Dali; Handorf, Elizabeth A.; Bellacosa, Alfonso; Testa, Joseph R.; Nussenzweig, Andre; Gupta, Gaorav P.; Sykes, Stephen M.; Johnson, Neil 分享 收藏
BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance Nacson, Joseph; Krais, John J.; Bernhardy, Andrea J.; Clausen, Emma; Feng, Wanjuan; Wang, Yifan; Nicolas, Emmanuelle; Cai, Kathy Q.; Tricarico, Rossella; Hua, Xiang; DiMarcantonio, Daniela; Martinez, Esteban; Zong, Dali; Handorf, Elizabeth A.; Bellacosa, Alfonso; Testa, Joseph R.; Nussenzweig, Andre; Gupta, Gaorav P.; Sykes, Stephen M.; Johnson, Neil 分享 收藏
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia Rudat, S.; Pfaus, A.; Cheng, Y. Y.; Holtmann, J.; Ellegast, J. M.; Buehler, C.; Di Marcantonio, D.; Martinez, E.; Goellner, S.; Wickenhauser, C.; Mueller-Tidow, C.; Lutz, C.; Bullinger, L.; Milsom, M. D.; Sykes, S. M.; Froehling, S.; Scholl, C. 分享 收藏
The-2518 A/G polymorphism of the monocyte chemoattractant protein-1 as a candidate genetic predisposition factor for secondary myelofibrosis and biomarker of disease severity Masselli, Elena; Carubbi, Cecilia; Cambo, Benedetta; Pozzi, Giulia; Gobbi, Giuliana; Mirandola, Prisco; Follini, Elena; Pagliaro, Luca; Di Marcantonio, Daniela; Bonatti, Francesco; Percesepe, Antonio; Sykes, Stephen M.; Aversa, Franco; Vitale, Marco 分享 收藏
Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia Di Marcantonio, Daniela; Martinez, Esteban; Sidoli, Simone; Vadaketh, Jessica; Nieborowska-Skorska, Margaret; Gupta, Anushk; Meadows, Jacob Michael; Ferraro, Francesca; Masselli, Elena; Challen, Grant A.; Milsom, Michael D.; Schoell, Claudia; Frohling, Stefan; Balachandran, Siddharth; Skorski, Tomasz; Garcia, Benjamin A.; Mirandola, Prisco; Gobbi, Giuliana; Garzon, Ramiro; Vitale, Marco; Sykes, Stephen M. 分享 收藏
MLL-AF9 leukemias are sensitive to PARP1 inhibitors combined with cytotoxic drugs MLL-AF9白血病对PARP1抑制剂联合细胞毒性药物敏感 Maifrede, Silvia; Martinez, Esteban; Nieborowska-Skorska, Margaret; Di Marcantonio, Daniela; Hulse, Michael; Le, Bac Viet; Zhao, Huaqing; Piwocka, Katarzyna; Tempera, Italo; Sykes, Stephen M.; Skorski, Tomasz 分享 收藏
Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells Nieborowska-Skorska, Margaret; Sullivan, Katherine; Dasgupta, Yashodhara; Podszywalow-Bartnicka, Paulina; Hoser, Grazyna; Maifrede, Silvia; Martinez, Esteban; Di Marcantonio, Daniela; Bolton-Gillespie, Elisabeth; Cramer-Morales, Kimberly; Lee, Jaewong; Li, Min; Slupianek, Artur; Gritsyuk, Daniel; Cerny-Reiterer, Sabine; Seferynska, Ilona; Stoklosa, Tomasz; Bullinger, Lars; Zhao, Huaqing; Gorbunova, Vera; Piwocka, Katarzyna; Valent, Peter; Civin, Curt I.; Muschen, Markus; Dick, John E.; Wang, Jean C. Y.; Bhatia, Smita; Bhatia, Ravi; Eppert, Kolja; Minden, Mark D.; Sykes, Stephen M.; Skorski, Tomasz 分享 收藏
JUN is a key transcriptional regulator of the unfolded protein response in acute myeloid leukemia Zhou, C.; Martinez, E.; Di Marcantonio, D.; Solanki-Patel, N.; Aghayev, T.; Peri, S.; Ferraro, F.; Skorski, T.; Scholl, C.; Frohling, S.; Balachandran, S.; Wiest, D. L.; Sykes, S. M. 分享 收藏
PKCε as a novel promoter of skeletal muscle differentiation and regeneration Di Marcantonio, D.; Galli, D.; Carubbi, C.; Gobbi, G.; Queirolo, V.; Martini, S.; Merighi, S.; Vaccarezza, M.; Maffulli, N.; Sykes, S. M.; Vitale, M.; Mirandola, P. 分享 收藏
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