Máté Gyimesi - Publications, H-index & Citations

Máté Gyimesi

motorpharma limited

15H指数

51论文数

778被引数

收录论文 33

发表时间

Fragment-based structure-activity relationship analysis of CK-571 reveals non-interacting groups drive smooth muscle myosin selectivity CK-571的基于片段的结构-活性关系分析揭示了非相互作用基团驱动平滑肌肌球蛋白的选择性

European Journal of Medicinal Chemistry

IF5.9

2025-12-16

PREAI

Sharad Kumar Suthar; Tamás Jernei; Csilla Kurdi; Ádam I. Horváth; Anna Ágnes Rauscher; Máté Gyimesi; András Málnási-Csizmadia

Comprehensive SAR Analysis of Actomyolytics, Drug Candidates Targeting the Actomyosin Complex 综合SAR分析：Actomyolytics及靶向Actomyosin复合物的药物候选物

European Journal of Medicinal Chemistry

IF5.9

2025-08-09

OAAI

Sharad Kumar Suthar; Tamás Szimler; Máté Pénzes; Sushmitha Chandrabhas; Anna Á. Rauscher; István Lőrincz; György Hegyi; Csilla Kurdi; Gábor Glatz; Zoltán Szőnyegi; Mihály Kovács; András Szabó; Máté Gyimesi; András Málnási-Csizmadia

The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom's syndrome helicase for efficient disruption of D-loops

NATURE COMMUNICATIONS

IF15.7

2022-02-03

OAAI

Harami, Gabor M.; Palinkas, Janos; SeoI, Yeonee; Kovacs, Zoltan J.; Gyimesi, Mate; Harami-Papp, Hajnalka; Neuman, Keir C.; Kovacs, Mihaly

Chiral HPLC separation of enantiomeric blebbistatin derivatives and racemization analysis in vertebrate tissues

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2021-09-01

PREAI

Suthar, Sharad Kumar; Rauscher, Anna A.; Winternitz, Mate; Gyimesi, Mate; Malnasi-Csizmadia, Andras

First-In-Class Anti-Spastic Drug Candidate (MPH-220) Efficiently Relaxes Spastic Muscles and Improves Motor Functions in Gait Disorder in Preclinical Studies.

STROKE

IF8.9

2021-03-01

PREAI

Gyimesi, Mate; Horvath, Adam; Turos, Demeter; Penzes, Mate; Kurdi, Csilla; Kovacs, Mihaly; Malnasi-Csizmadia, Andras

Direct Myosin-2 Inhibition Restores Cerebral Perfusion in Cortical and Subcortical Regions Resulting in Functional Improvement After Ischemic Stroke.

STROKE

IF8.9

2021-03-01

PREAI

Penzes, Mate; Turos, Demeter; Mathe, Domokos; Rauscher, Anna; Toth, Peter; Ivic, Ivan; Gyimesi, Mate; Doboi, Arpad; Malnasi-Csizmadia, Andras

Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2021-03-01

OAAI

Gyimesi, Mate; Rauscher, Anna A.; Suthar, Sharad Kumar; Hamow, Kamiran A.; Oravecz, Kinga; Lorincz, Istvan; Borhegyi, Zsolt; Deri, Mate T.; Kiss, Adam F.; Monostory, Katalin; Szabo, Pal Tamas; Nag, Suman; Tomasic, Ivan; Krans, Jacob; Tierney, Patrick J.; Kovacs, Mihaly; Kornya, Laszlo; Malnasi-Csizmadia, Andras

Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion

SCIENTIFIC REPORTS

IF3.9

2020-08-07

OAAI

Horvath, Adam, I; Gyimesi, Mate; Varkuti, Boglarka H.; Kepiro, Miklos; Szegvari, Gabor; Lorincz, Istvan; Hegyi, Gyorgy; Kovacs, Mihaly; Malnasi-Csizmadia, Andras

Direct myosin-2 inhibition enhances cerebral perfusion resulting in functional improvement after ischemic stroke

THERANOSTICS

IF13.3

2020-01-01

OAAI

Penzes, Mate; Turos, Demeter; Mathe, Domokos; Szigeti, Krisztian; Hegedus, Nikolett; Rauscher, Anna Agnes; Toth, Peter; Ivic, Ivan; Padmanabhan, Parasuraman; Pal, Gabriella; Dobolyi, Arpad; Gyimesi, Mate; Malnasi-Csizmadia, Andras

Novel Assay Resolves D-Loop Processing Pathways by E-Coli RecQ and Human BLM Helicases

BIOPHYSICAL JOURNAL

IF3.1

2019-02-01

PREAI

Harami, Gabor M.; Palinkas, Janos; Seol, Yeonee; Gyimesi, Mate; Kovacs, Zoltan J.; Neuman, Keir C.; Kovacs, Mihaly

Targeting Myosin by Blebbistatin Derivatives: Optimization and Pharmacological Potential 布比他汀衍生物靶向肌球蛋白: 优化和药理潜力

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2018-09-01

PREAI

Rauscher, Anna A.; Gyimesi, Mate; Kovacs, Mihaly; Malnasi-Csizmadia, Andras

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state

NUCLEIC ACIDS RESEARCH

IF13.1

2018-02-22

OAAI

Spirek, Mario; Mlcouskova, Jarmila; Belan, Ondrej; Gyimesi, Mate; Harami, Gabor M.; Molnar, Eszter; Novacek, Jiri; Kovacs, Mihaly; Krejci, Lumir

RecQ helicase triggers a binding mode change in the SSB-DNA complex to efficiently initiate DNA unwinding

NUCLEIC ACIDS RESEARCH

IF13.1

2017-10-20

OAAI

Mills, Maria; Harami, Gabor M.; Seol, Yeonee; Gyimesi, Mate; Martina, Mate; Kovacs, Zoltan J.; Kovacs, Mihaly; Neuman, Keir C.

Holliday Junction Structure Development for Single-Molecule Visualization

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Gyimesi, Mate; Kovacs, Zoltan; Kovacs, Mihaly

Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination 沿DNA穿梭并通过RecQ解旋酶定向加工D环支持同源重组的质量控制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-01-09

OAAI

Harami, Gabor M.; Seol, Yeonee; In, Junghoon; Ferencziova, Veronika; Martina, Mate; Gyimesi, Mate; Sarlos, Kata; Kovacs, Zoltan J.; Nagy, Nikolett T.; Sun, Yuze; Vellai, Tibor; Neuman, Keir C.; Kovacs, Mihaly

Recent adaptations of fluorescence techniques for the determination of mechanistic parameters of helicases and translocases

METHODS

IF4.3

2016-10-01

PREAI

Gyimesi, Mate; Harami, Gabor M.; Kocsis, Zsuzsa S.; Kovacs, Mihaly

Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations

NUCLEIC ACIDS RESEARCH

IF13.1

2014-12-24

OAAI

Sarlos, Kata; Gyimesi, Mate; Kele, Zoltan; Kovacs, Mihaly