Yanxiang Zhao

the hong kong polytechnic university

H指数:26

被引数:6,391

个人简介

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教育背景

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工作经历

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荣誉奖项

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SERPINB3 enhances NPM1 sumoylation via inhibiting SENP3’s activity and promotes lung tumorigenesis

SERPINB3通过抑制SENP3的活性增强NPM1的SUMO化并促进肺癌发生。

Cell Death & Disease

IF9.6

2025-12-240

OAAI

Autophagy-Targeting Stapled Peptide Utilizes Macropinocytosis for Cell Entry to Potentiate Anti-Proliferative Autosis in Small-Cell Lung Cancer

靶向自噬的嵌合肽利用巨胞饮作用进入细胞，以增强小细胞肺癌中的抗增殖自噬性细胞死亡

Pharmaceutics

IF5.5

2025-11-260

OAAI

NRBF2 homodimerization by its coiled-coil domain strengthens association with the PtdIns3K complex mediated by the MIT domain to promote autophagy

NRBF2通过其卷曲螺旋结构域形成的同源二聚体，增强了与由MIT结构域介导的PtdIns3K复合物的结合，以促进自噬。

Autophagy

IF14.3

2025-11-120

Human YKT6 forms priming complex with STX17 and SNAP29 to facilitate autophagosome-lysosome fusion

CELL REPORTS

IF6.9

2024-02-013

An autophagy-inducing stapled peptide induces mitochondria dysfunction and triggers autotic cell death in triple-negative breast cancer

CELL DEATH DISCOVERY

IF7

2023-08-192

OAAI

The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs

AUTOPHAGY

IF14.3

2023-07-131

PRE

The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression

NATURE COMMUNICATIONS

IF15.7

2023-03-226

OAAI

Unconventional tonicity-regulated nuclear trafficking of NFAT5 mediated by KPNB1, XPOT and RUVBL2

JOURNAL OF CELL SCIENCE

IF3.6

2022-07-125

OAAI

Y Optimization of Beclin 1-Targeting Stapled Peptides by Staple Scanning Leads to Enhanced Antiproliferative Potency in Cancer Cells

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-09-1015

Regulation of Antigenic Variation by Trypanosoma brucei Telomere Proteins Depends on Their Unique DNA Binding Activities

PATHOGENS

IF3.3

2021-07-3011

OAAI

SCIENCE ADVANCES

IF12.5

2021-02-1911

OAAI

TbRAP1 has an unusual duplex DNA binding activity required for its telomere localization and VSG silencing

SCIENCE ADVANCES

IF12.5

2020-09-1811

OAAI

The hydrolytic water molecule of Class A β-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis

SCIENTIFIC REPORTS

IF3.9

2020-06-2323

OAAI

ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway

AUTOPHAGY

IF14.3

2019-07-30145

OAAI

Small molecule inhibits respiratory syncytial virus entry and infection by blocking the interaction of the viral fusion protein with the cell membrane

小分子通过阻断呼吸道合胞病毒融合蛋白与细胞膜的相互作用抑制病毒进入和感染

FASEB JOURNAL

IF4.2

2018-12-2030

OAAI

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-06-0455

OAAI

Modified Penicillin Molecule with Carbapenem- Like Stereochemistry Specifically Inhibits Class C β-Lactamases

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2017-12-0111

OAAI

Crystallographic Snapshots of Class A β-Lactamase Catalysis Reveal Structural Changes That Facilitate β-Lactam Hydrolysis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-03-0124

OAAI

Thermodynamic selectivity of functional agents on zeolite for sodium dodecyl sulfate sequestration

功能剂在沸石上用于十二烷基硫酸钠螯合的热力学选择性

JOURNAL OF HAZARDOUS MATERIALS

IF11.3

2016-11-013

PREAI

Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates

PLOS GENETICS

IF3.7

2015-02-27268

OAAI

Yanxiang Zhao

个人简介

教育背景

工作经历

荣誉奖项

研究方向