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D

David C. Chan

California Institute of Technology

75H指数
179论文数
4.0W被引数
收录论文 94
发表时间
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Regulation of mitophagy by Fis1 and Fascin1-organized actinFis1和Fascin1组织肌动蛋白对线粒体自噬的调控
errCurrent Biology
IF7.5
err2026-02-24
err0
errOAAI
errShintaro Nakajima; Ting-Yu Wang; Tsui-Fen Chou; Yogaditya Chakrabarty; David C. Chan
err分享
err收藏
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tetherRHOA通过调节VAPB/PTPIP51连接蛋白来调控线粒体-内质网接触位点。
errNature Communications
IF15.7
err2025-12-14
err0
errOAAI
errZheng Yang; Shintaro Nakajima; Hsiuchen Chen; Yogaditya Chakrabarty; Huibao Feng; David C. Chan
err分享
err收藏
Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress假定的PINK1/Parkin激活剂通过使细胞对线粒体应激更敏感来降低自噬的阈值。
errScience Advances
IF12.5
err2025-08-27
err0
PREAI
errWilliam M. Rosencrans; Ryan W. Lee; Logan McGraw; Ian Horsburgh; Ting-Yu Wang; Baiyi Quan; Diana Huynh; Jennifer A. Johnston; David C. Chan; Tsui-Fen Chou
err分享
err收藏
LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetesLONP1调控线粒体蛋白质折叠为理解2型糖尿病中的β细胞衰竭提供了见解
errNature Metabolism
IF20.8
err2025-07-21
err0
errOAAI
errJin Li; Yamei Deng; Marie Gasser; Jie Zhu; Emily M. Walker; Vaibhav Sidarala; Emma C. Reck; Dre L. Hubers; Mabelle B. Pasmooij; Chun-Shik Shin; Khushdeep Bandesh; Eftyhmios Motakis; Siddhi Nargund; Romy Kursawe; Venkatesha Basrur; Alexey I. Nesvizhskii; Michael L. Stitzel; David C. Chan; Guy A. Rutter; Scott A. Soleimanpour
err分享
err收藏
The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria线粒体自噬受体BNIP3和NIX介导隔离膜与线粒体的紧密附着和扩张。
errJOURNAL OF CELL BIOLOGY
IF6.4
err2025-05-13
err0
errOAAI
errYamashita, Shun-ichi; Arai, Ritsuko; Hada, Hiroshi; Padman, Benjamin Scott; Lazarou, Michael; Chan, David C.; Kanki, Tomotake; Waguri, Satoshi
err分享
err收藏
Development of a Signal-integrating Reporter to Monitor Mitochondria-ER Contacts
errACS SYNTHETIC BIOLOGY
IF3.9
err2024-08-20
err0
errOAAI
errYang, Zheng; Chan, David C.
err分享
err收藏
Lipidomics reveals the reshaping of the mitochondrial phospholipid profile in cells lacking OPA1 and mitofusins
errJOURNAL OF LIPID RESEARCH
IF4.1
err2024-06-01
err0
errOAAI
errCastellaneta, Andrea; Losito, Ilario; Porcelli, Vito; Barile, Serena; Maresca, Alessandra; Del Dotto, Valentina; Losacco, Valentina; Guadalupi, Ludovica Sofia; Calvano, Cosima Damiana; Chan, David C.; Carelli, Valerio; Palmieri, Luigi; Cataldi, Tommaso R. I.
err分享
err收藏
Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2024-03-22
err11
PREAI
errYamashita, Shun-ichi; Sugiura, Yuki; Matsuoka, Yuta; Maeda, Rae; Inoue, Keiichi; Furukawa, Kentaro; Fukuda, Tomoyuki; Chan, David C.; Kanki, Tomotake
err分享
err收藏
The HRI branch of the integrated stress response selectively triggers mitophagy
errMOLECULAR CELL
IF16.6
err2024-03-01
err6
errOAAI
errChakrabarty, Yogaditya; Yang, Zheng; Chen, Hsiuchen; Chan, David C.
err分享
err收藏
In situ architecture of Opa1-dependent mitochondrial cristae remodeling
errEMBO JOURNAL
IF8.3
err2024-01-15
err9
errOAAI
errFry, Michelle Y.; Navarro, Paula P.; Hakim, Pusparanee; Ananda, Virly Y.; Qin, Xingping; Landoni, Juan C.; Rath, Sneha; Inde, Zintis; Lugo, Camila Makhlouta; Luce, Bridget E.; Ge, Yifan; Mcdonald, Julie L.; Ali, Ilzat; Ha, Leillani L.; Kleinstiver, Benjamin P.; Chan, David C.; Sarosiek, Kristopher A.; Chao, Luke H.
err分享
err收藏
Control of mitochondrial dynamics by a fusogenic lipid
errTRENDS IN CELL BIOLOGY
IF18.1
err2023-12-01
err0
PREAI
errYang, Zheng; Chan, David C.
err分享
err收藏
SIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err370
errOAAI
errSamant, Sadhana A.; Zhang, Hannah J.; Hong, Zhigang; Pillai, Vinodkumar B.; Sundaresan, Nagalingam R.; Wolfgeher, Donald; Archer, Stephen L.; Chan, David C.; Gupta, Mahesh P.
err分享
err收藏
A Heterozygous Mutation in MFF Associated with a Mild Mitochondrial PhenotypeMFF中与轻度线粒体表型相关的杂合突变
errJOURNAL OF NEUROMUSCULAR DISEASES
IF3.4
err2022-10-28
err2
PREAI
errMurata, Daisuke; Grunseich, Christopher; Iijima, Miho; Chan, David; Corse, Andrea; Hoke, Ahmet; Schindler, Alice; Sesaki, Hiromi; Roda, Ricardo H.
err分享
err收藏
Metabolic reprogramming in the OPA1-deficient cells
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2022-09-14
err4
PREAI
errDai, Wenting; Wang, Zhichao; Wang, Qiong A.; Chan, David; Jiang, Lei
err分享
err收藏
Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria
errNATURE COMMUNICATIONS
IF15.7
err2022-03-24
err30
errOAAI
errYang, Huan; Sibilla, Caroline; Liu, Raymond; Yun, Jina; Hay, Bruce A.; Blackstone, Craig; Chan, David C.; Harvey, Robert J.; Guo, Ming
err分享
err收藏
Solving neurodegeneration: common mechanisms and strategies for new treatments解决神经退行性疾病: 新疗法的常见机制和策略
errMOLECULAR NEURODEGENERATION
IF17.5
err2022-03-21
err123
errOAAI
errWareham, Lauren K.; Liddelow, Shane A.; Temple, Sally; Benowitz, Larry, I; Di Polo, Adriana; Wellington, Cheryl; Goldberg, Jeffrey L.; He, Zhigang; Duan, Xin; Bu, Guojun; Davis, Albert A.; Shekhar, Karthik; La Torre, Anna; Chan, David C.; Canto-Soler, M. Valeria; Flanagan, John G.; Subramanian, Preeti; Rossi, Sharyn; Brunner, Thomas; Bovenkamp, Diane E.; Calkins, David J.
err分享
err收藏
ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1
errEXPERIMENTAL AND MOLECULAR MEDICINE
IF12.9
err2021-11-26
err7
errOAAI
errSonn, Seong Keun; Seo, Seungwoon; Yang, Jaemoon; Oh, Ki Sook; Chen, Hsiuchen; Chan, David C.; Rhee, Kunsoo; Lee, Kyung S.; Yang, Young; Oh, Goo Taeg
err分享
err收藏
Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation
errDEVELOPMENT
IF3.6
err2021-08-12
err18
errOAAI
errVaruzhanyan, Grigor; Ladinsky, Mark S.; Yamashita, Shun-ichi; Abe, Manabu; Sakimura, Kenji; Kanki, Tomotake; Chan, David C.
err分享
err收藏
miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1 (vol 4, 30, 2021)
errCOMMUNICATIONS BIOLOGY
IF5.1
err2021-02-04
err2
errOAAI
errKato, Mitsuo; Abdollahi, Maryam; Tunduguru, Ragadeepthi; Tsark, Walter; Chen, Zhuo; Wu, Xiwei; Wang, Jinhui; Chen, Zhen Bouman; Lin, Feng-Mao; Lanting, Linda; Wang, Mei; Huss, Janice; Fueger, Patrick T.; Chan, David; Natarajan, Rama
err分享
err收藏
Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2021-01-15
err51
errOAAI
errWang, Ruohan; Mishra, Prashant; Garbis, Spiros D.; Moradian, Annie; Sweredoski, Michael J.; Chan, David C.
err分享
err收藏

研究方向

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合作学者
合作期刊
D
Don W. Cleveland
H 指数: 165 · 论文数: 525
C
Christine E. Seidman
H 指数: 151 · 论文数: 709
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H 指数: 141 · 论文数: 1.0K
邓
邓初夏 (Chu‐Xia Deng)
H 指数: 134 · 论文数: 833
P
Philip Leder
H 指数: 133 · 论文数: 472
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