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A

Arthur Van Aerschot

KU Leuven

H指数:43

被引数:7,046

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Rational fragment-based design of compounds targeting the PWWP domain of the HRP family

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-12-012

PRE

Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip

COMMUNICATIONS BIOLOGY

IF5.1

2022-08-293

OAAI

Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors

RSC CHEMICAL BIOLOGY

IF3.1

2022-01-013

OAAI

Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-02-0114

OAAI

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

IF4.6

2020-10-162

OAAI

Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-09-014

OAAI

Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase

靶向酪氨酰-或异亮氨酸-tRNA合成酶的苯基三唑官能化氨基磺酸盐抑制剂

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-08-0111

OAAI

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases

ACS CHEMICAL BIOLOGY

IF3.8

2019-12-2311

OAAI

Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases

ANTIBIOTICS-BASEL

IF4.6

2019-10-093

OAAI

Design of reverse transcriptase-specific nucleosides to visualize early steps of HIV-1 replication by click labeling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-08-017

OAAI

Comparative analysis of pyrimidine substituted aminoacyl-sulfamoyl nucleosides as potential inhibitors targeting class I aminoacyl-tRNA synthetases

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-07-019

PREAI

Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2019-07-018

OAAI

Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies

IF4.6

2019-01-289

OAAI

Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-03-0115

OAAI

Aminopurine and aminoquinazoline scaffolds for development of potential dengue virus inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-01-0126

OAAI

A Trojan-Horse Peptide-Carboxymethyl-Cytidine Antibiotic from Bacillus amyloliquefaciens

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2016-11-2927

OAAI

Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2016-10-0138

OAAI

Renaissance in Antibiotic Discovery: Some Novel Approaches for Finding Drugs to Treat Bad Bugs

CURRENT MEDICINAL CHEMISTRY

IF3.5

2015-06-247

OA

1′,5′-Anhydro-L-ribo-hexitol Adenine Nucleic Acids (α-L-HNA-A): Synthesis and Chiral Selection Properties in the Mirror Image World

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2015-04-3013

PREAI

Hybridisation Potential of 1',3'-Di-O-methylaltropyranoside Nucleic Acids

IF4.6

2015-03-032

OAAI