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Sergei V. Strelkov

KU Leuven

H指数:41

被引数:8,215

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De novo design of proteinaceous binders targeting the LEDGF PWWP domain

从头设计靶向LEDGF PWWP结构域的蛋白质结合剂

Protein Science

IF5.2

2026-09-270

PRE

High-Affinity Nanobody Against the LEDGF PWWP Domain Inhibits Chromatin Binding In Vitro

高亲和力纳米抗体针对LEDGF PWWP结构域在体外抑制染色质结合

IF4.8

2026-05-130

OAAI

DDtrek: A PyMOL-Based Management System for 3D Structural Data Series

DDtrek: 一个基于PyMOL的3D结构数据系列管理系统

IF4.3

2025-05-160

OA

Rational fragment-based design of compounds targeting the PWWP domain of the HRP family

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-12-012

PRE

Molecular structure of soluble vimentin tetramers (vol 13, 8841, 2023)

SCIENTIFIC REPORTS

IF3.9

2024-11-200

OAAI

A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors

MICROBIOLOGY SPECTRUM

IF3.8

2024-03-053

OAAI

Molecular structure of soluble vimentin tetramers

SCIENTIFIC REPORTS

IF3.9

2023-05-3115

OAAI

Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip

COMMUNICATIONS BIOLOGY

IF5.1

2022-08-293

OAAI

Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors

RSC CHEMICAL BIOLOGY

IF3.1

2022-01-013

OAAI

Molecular Interactions Driving Intermediate Filament Assembly

分子相互作用驱动中间丝组装

IF5.2

2021-09-1727

OAAI

Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-02-0114

OAAI

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

IF4.6

2020-10-162

OAAI

Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-09-014

OAAI

Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase

靶向酪氨酰-或异亮氨酸-tRNA合成酶的苯基三唑官能化氨基磺酸盐抑制剂

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-08-0111

OAAI

Effect of cataract-associated mutations in the N-terminal domain of αB-crystallin (HspB5)

EXPERIMENTAL EYE RESEARCH

IF2.7

2020-08-019

PREAI

Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions

IF5.2

2020-07-0712

OAAI

Mutations in HspB1 and hereditary neuropathies

CELL STRESS & CHAPERONES

IF3.2

2020-07-0115

OAAI

Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2020-03-0114

OAAI

Lateral A11 type tetramerization in lamins

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2020-01-0125

OAAI

Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases

ACS CHEMICAL BIOLOGY

IF3.8

2019-12-2311

OAAI