Martin Oti - Publications, H-index & Citations

Martin Oti

boehringer ingelheim

21H指数

52论文数

2.5K被引数

收录论文 23

发表时间

STARR-CRAAVT: A platform to identify cell type-specific regulatory elements for next-generation gene therapy STARR-CRAAVT：用于识别下一代基因治疗中细胞类型特异性调控元件的平台

iScience

IF4.1

2026-03-25

OAAI

Robert Becker; Priyanka Choudhury; Martin Oti; Youssef Fouani; Benjamin Strobel; Stephanie Ketterer; Simon Rumpel; John Park; Sebastian Kreuz; Udo Maier; Stefan Michelfelder; Christian Schön

Genetic Inactivation of the Serotonin Transporter Dysregulates Expression of Neurotransmission Genes and Genome-Wide DNA Methylation Levels in the Medial Prefrontal Cortex of Male Rats During Postnatal Development 5-羟色胺转运蛋白的遗传失活扰乱了雄性大鼠在出生后发育期间内侧前额叶皮质中神经递质基因的表达和全基因组DNA甲基化水平。

Developmental Neurobiology

IF2.3

2025-06-08

OAAI

Yvet Kroeze; Martin Oti; Roel H. M. Cooijmans; Ellen van Beusekom; Leonie I. Kroeze; Anthonieke Middelman; Hans van Bokhoven; Sharon M. Kolk; Judith R. Homberg; Huiqing Zhou

AAV yield, bioactivity, and particle heterogeneity are impacted by genome size and non-coding DNA elements AAV产量、生物活性和颗粒异质性受基因组大小和非编码DNA元件的影响。

Molecular Therapy Methods & Clinical Development

IF4.7

2025-06-02

OAAI

Gina Blahetek; Benjamin Lindner; Martin Oti; Christian Schön; Benjamin Strobel

Mapping administration route-dependent transduction profiles of commonly used AAV variants in mice by barcode amplicon sequencing 通过条形码扩增子测序绘制常用AAV变体在小鼠中与给药途径相关的转导谱图

MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT

IF4.7

2025-06-01

OAAI

Sarah Abele; Gregorio Alanis-Lobato; Martin Oti; Werner Rust; Dragica Blazevic; Jenny Danner-Liskus; Christine Mayer; Gudrun Zimmermann; Kai Zuckschwerdt; Tanja Schönberger; Peter Gross; Charlotte Lempp; Stefan Michelfelder; Benjamin Strobel

An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo

SCIENTIFIC REPORTS

IF3.9

2023-04-25

OAAI

Chan, Ya-Chien; Kienle, Eike; Oti, Martin; Di Liddo, Antonella; Mendez-Lago, Maria; Aschauer, Dominik F.; Peter, Manuel; Pagani, Michaela; Arnold, Cosmas; Vonderheit, Andreas; Schoen, Christian; Kreuz, Sebastian; Stark, Alexander; Rumpel, Simon

Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis 通过JNK-iASPP-AP1轴抑制突变Ras和炎症驱动的皮肤肿瘤发生

CELL REPORTS

IF6.9

2022-10-01

OAAI

Al Moussawi, Khatoun; Chung, Kathryn; Carroll, Thomas M.; Osterburg, Christian; Smirnov, Artem; Lotz, Rebecca; Miller, Paul; Dedeic, Zinaida; Zhong, Shan; Oti, Martin; Kouwenhoven, Evelyn N.; Asher, Ruth; Goldin, Robert; Tellier, Michael; Murphy, Shona; Zhou, Huiqing; Dotsch, Volker; Lu, Xin

TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network

MOLECULAR CELL

IF16.6

2019-06-01

OAAI

Seruggia, Davide; Oti, Martin; Tripathi, Pratibha; Canver, Matthew C.; LeBlanc, Lucy; Di Giammartino, Dafne C.; Bullen, Michael J.; Nefzger, Christian M.; Sun, Yu Bo Yang; Farouni, Rick; Polo, Jose M.; Pinello, Luca; Apostolou, Effie; Kim, Jonghwan; Orkin, Stuart H.; Das, Partha Pratim

Mutant p63 Affects Epidermal Cell Identity through Rewiring the Enhancer Landscape

CELL REPORTS

IF6.9

2018-12-01

OAAI

Qu, Jieqiong; Tanis, Sabine E. J.; Smits, Jos P. H.; Kouwenhoven, Evelyn N.; Oti, Martin; van den Bogaard, Ellen H.; Logie, Colin; Stunnenberg, Hendrik G.; van Bokhoven, Hans; Mulder, Klaas W.; Zhou, Huiqing

Establishing normal metabolism and differentiation in hepatocellular carcinoma cells by culturing in adult human serum

SCIENTIFIC REPORTS

IF3.9

2018-08-03

OAAI

Steenbergen, Rineke; Oti, Martin; ter Horst, Rob; Tat, Wilson; Neufeldt, Chris; Belovodskiy, Alexandr; Chua, Tiing Tiing; Cho, Woo Jung; Joyce, Michael; Dutilh, Bas E.; Tyrrell, D. Lorne

Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2017-05-01

OAAI

Ngcungcu, Thandiswa; Oti, Martin; Sitek, Jan C.; Haukanes, Bjorn I.; Linghu, Bolan; Bruccoleri, Robert; Stokowy, Tomasz; Oakeley, Edward J.; Yang, Fan; Zhu, Jiang; Sultan, Marc; Schalkwijk, Joost; van Vlijmen-Willems, Ivonne M. J. J.; von der Lippe, Charlotte; Brunner, Han G.; Ersland, Kari M.; Grayson, Wayne; Buechmann-Moller, Stine; Sundnes, Olav; Nirmala, Nanguneri; Morgan, Thomas M.; van Bokhoven, Hans; Steen, Vidar M.; Hull, Peter R.; Szustakowski, Joseph; Staedtler, Frank; Zhou, Huiqing; Fiskerstrand, Torunn; Ramsay, Michele

Sequence variation between 462 human individuals fine-tunes functional sites of RNA processing

SCIENTIFIC REPORTS

IF3.9

2016-09-12

OAAI

Ferreira, Pedro G.; Oti, Martin; Barann, Matthias; Wieland, Thomas; Ezquina, Suzana; Friedlander, Marc R.; Rivas, Manuel A.; Esteve-Codina, Anna; Rosenstiel, Philip; Strom, Tim M.; Lappalainen, Tuuli; Guigo, Roderic; Sammeth, Michael

CTCF-mediated chromatin loops enclose inducible gene regulatory domains CTCF介导的染色质环包围可诱导的基因调控域

BMC GENOMICS

IF3.7

2016-03-22

OAAI

Oti, Martin; Falck, Jonas; Huynen, Martijn A.; Zhou, Huiqing

A homozygous FITM2 mutation causes a deafness-dystonia syndrome with motor regression and signs of ichthyosis and sensory neuropathy

DISEASE MODELS & MECHANISMS

IF3.3

2016-01-01

OAAI

Seco, Celia Zazo; Castells-Nobau, Anna; Joo, Seol-hee; Schraders, Margit; Foo, Jia Nee; van der Voet, Monique; Velan, S. Sendhil; Nijhof, Bonnie; Oostrik, Jaap; de Vrieze, Erik; Katana, Radoslaw; Mansoor, Atika; Huynen, Martijn; Szklarczyk, Radek; Oti, Martin; Tranebjaerg, Lisbeth; van Wijk, Erwin; Scheffer-de Gooyert, Jolanda M.; Siddique, Saadat; Baets, Jonathan; de Jonghe, Peter; Kazmi, Syed Ali Raza; Sadananthan, Suresh Anand; van de Warrenburg, Bart P.; Khor, Chiea Chuen; Goepfert, Martin C.; Qamar, Raheel; Schenck, Annette; Kremer, Hannie; Siddiqi, Saima

Systematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts

HUMAN GENETICS

IF3.6

2015-11-11

OAAI

Conte, Federica; Oti, Martin; Dixon, Jill; Carels, Carine E. L.; Rubini, Michele; Zhou, Huiqing

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation

EMBO REPORTS

IF6.2

2015-06-01

137

OAAI

Kouwenhoven, Evelyn N.; Oti, Martin; Niehues, Hanna; van Heeringen, Simon J.; Schalkwijk, Joost; Stunnenberg, Hendrik G.; van Bokhoven, Hans; Zhou, Huiqing

Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila

PLOS GENETICS

IF3.7

2013-10-31

OAAI

Oortveld, Merel A. W.; Keerthikumar, Shivakumar; Oti, Martin; Nijhof, Bonnie; Fernandes, Ana Clara; Kochinke, Korinna; Castells-Nobau, Anna; van Engelen, Eva; Ellenkamp, Thijs; Eshuis, Lilian; Galy, Anne; van Bokhoven, Hans; Habermann, Bianca; Brunner, Han G.; Zweier, Christiane; Verstreken, Patrik; Huynen, Martijn A.; Schenck, Annette

De Novo Mutations in the Genome Organizer CTCF Cause Intellectual Disability

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2013-07-01

155

OAAI

Gregor, Anne; Oti, Martin; Kouwenhoven, Evelyn N.; Hoyer, Juliane; Sticht, Heinrich; Ekici, Arif B.; Kjaergaard, Susanne; Rauch, Anita; Stunnenberg, Hendrik G.; Uebe, Steffen; Vasileiou, Georgia; Reis, Andre; Zhou, Huiqing; Zweier, Christiane

Genome-Wide Profiling of p63 DNA-Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus

PLOS GENETICS

IF3.7

2010-08-19

163

OAAI

Kouwenhoven, Evelyn N.; van Heeringen, Simon J.; Tena, Juan J.; Oti, Martin; Dutilh, Bas E.; Alonso, M. Eva; de la Calle-Mustienes, Elisa; Smeenk, Leonie; Rinne, Tuula; Parsaulian, Lilian; Bolat, Emine; Jurgelenaite, Rasa; Huynen, Martijn A.; Hoischen, Alexander; Veltman, Joris A.; Brunner, Han G.; Roscioli, Tony; Oates, Emily; Wilson, Meredith; Manzanares, Miguel; Luis Gomez-Skarmeta, Jose; Stunnenberg, Hendrik G.; Lohrum, Marion; van Bokhoven, Hans; Zhou, Huiqing

The Biological Coherence of Human Phenome Databases

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2009-12-01

OAAI

Oti, Martin; Huynen, Martijn A.; Brunner, Han G.

Conservation of divergent transcription in fungi

TRENDS IN GENETICS

IF16.3

2008-05-01

PREAI

Kensche, Philip R.; Oti, Martin; Dutilh, Bas E.; Huynen, Martijn A.

研究方向