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收藏分享 收藏 Cinacalcet Reverses Short QT Interval in Familial Hypocalciuric Hypercalcemia Type 1
Cuny, Thomas; Romanet, Pauline; Goldsworthy, Michelle; Guerin, Carole; Wilkin, Marie; Roche, Philippe; Sebag, Frederic; van Summeren, Lynn E.; Stevenson, Mark; Howles, Sarah A.; Deharo, Jean-Claude; Thakker, Rajesh, V; Taieb, David 分享 收藏 From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemiaSaez-Ayala, Magali; Hoffer, Laurent; Abel, Sebastien; Ben Yaala, Khaoula; Sicard, Benoit; Andrieu, Guillaume P.; Latiri, Mehdi; Davison, Emma K.; Ciufolini, Marco A.; Bremond, Paul; Rebuffet, Etienne; Roche, Philippe; Derviaux, Carine; Voisset, Edwige; Montersino, Camille; Castellano, Remy; Collette, Yves; Asnafi, Vahid; Betzi, Stephane; Dubreuil, Patrice; Combes, Sebastien; Morelli, Xavier 分享 收藏 Discovery of a PDZ Domain Inhibitor Targeting the Syndecan/ Syntenin Protein-Protein Interaction: A Semi-Automated Hit Identification-to-Optimization ApproachHoffer, Laurent; Garcia, Manon; Leblanc, Raphael; Feracci, Mikael; Betzi, Stephane; Ben Yaala, Khaoula; Daulat, Avais M.; Zimmermann, Pascale; Roche, Philippe; Barral, Karine; Morelli, Xavier 分享 收藏 分享 收藏 CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug ModulationCarrasco, Kendall; Montersino, Camille; Derviaux, Carine; Saez-Ayala, Magali; Hoffer, Laurent; Restouin, Audrey; Castellano, Remy; Casassa, Justine; Roche, Philippe; Pasquier, Eddy; Combes, Sebastien; Morelli, Xavier; Collette, Yves; Betzi, Stephane 分享 收藏 Fragment-based drug design targeting syntenin PDZ2 domain involved in exosomal release and tumour spreadGarcia, Manon; Hoffer, Laurent; Leblanc, Raphael; Benmansour, Fatiha; Feracci, Mikael; Derviaux, Carine; Egea-Jimenez, Antonio Luis; Roche, Philippe; Zimmermann, Pascale; Morelli, Xavier; Barral, Karine 分享 收藏 Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loading with syndecan and EpCAM cargosyntenin PDZ2结构域的药理学抑制会损害乳腺癌细胞的活性以及syndecan和EpCAM货物的外泌体负载Leblanc, R.; Kashyap, R.; Barral, K.; Egea-Jimenez, A. L.; Kovalskyy, D.; Feracci, M.; Garcia, M.; Derviaux, C.; Betzi, S.; Ghossoub, R.; Platonov, M.; Roche, P.; Morelli, X.; Hoffer, L.; Zimmermann, Pascale 分享 收藏 Fr-PPIChem: An Academic Compound Library Dedicated to Protein- Protein InteractionsBosc, Nicolas; Muller, Christophe; Hoffer, Laurent; Lagorce, David; Bourg, Stephane; Derviaux, Carine; Gourdel, Marie-Edith; Rain, Jean-Christophe; Miller, Thomas W.; Villoutreix, Bruno O.; Miteva, Maria; Bonnet, Pascal; Morelli, Xavier; Sperandio, Olivier; Roche, Philippe 分享 收藏 A gain-of-function RAC2 mutation is associated with bone marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiencyLagresle-Peyrou, Chantal; Olichon, Aurelien; Sadek, Hanem; Roche, Philippe; Tardy, Claudine; Da Silva, Cindy; Garrigue, Alexandrine; Fischer, Alain; Moshous, Despina; Collette, Yves; Picard, Capucine; Casanova, Jean Laurent; Andre, Isabelle; Cavazzana, Marina 分享 收藏 A divergent CheW confers plasticity to nucleoid-associated chemosensory arraysGuiseppi, Annick; Vicente, Juan Jesus; Herrou, Julien; Byrne, Deborah; Barneoud, Aurelie; Moine, Audrey; Espinosa, Leon; Basse, Marie-Jeanne; Molle, Virginie; Mignot, Tam; Roche, Philippe; Mauriello, Emilia M. F. 分享 收藏 Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcusde Groot, Arjan; Siponen, Marina, I; Magerand, Romaric; Eugenie, Nicolas; Martin-Arevalillo, Raquel; Doloy, Jade; Lemaire, David; Brandelet, Geraldine; Parcy, Francois; Dumas, Renaud; Roche, Philippe; Servant, Pascale; Confalonieri, Fabrice; Arnoux, Pascal; Pignol, David; Blanchard, Laurence 分享 收藏 分享 收藏 分享 收藏 Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis ApproachHoffer, Laurent; Voitovich, Yuliia V.; Raux, Brigitt; Carrasco, Kendall; Muller, Christophe; Fedorov, Aleksey Y.; Derviaux, Carine; Amouric, Agnes; Betzi, Stephane; Horvath, Dragos; Varnek, Alexandre; Collette, Yves; Combes, Sebastien; Roche, Philippe; Morelli, Xavier 分享 收藏 18F-FDOPA PET/CT Imaging of MAX-Related PheochromocytomaTaieb, David; Jha, Abhishek; Guerin, Carole; Pang, Ying; Adams, Karen T.; Chen, Clara C.; Romanet, Pauline; Roche, Philippe; Essamet, Wassim; Ling, Alexander; Quezado, Martha M.; Castinetti, Frederic; Sebag, Frederic; Pacak, Karel 分享 收藏 Modulation of Re-initiation of Measles Virus Transcription at Intergenic Regions by PXD to NTAIL Binding StrengthBloyet, Louis-Marie; Brunel, Joanna; Dosnon, Marion; Hamon, Veronique; Erales, Jenny; Gruet, Antoine; Lazert, Carine; Bignon, Christophe; Roche, Philippe; Longhi, Sonia; Gerlier, Denis 分享 收藏 Pathological and Genetic Characterization of Bilateral Adrenomedullary Hyperplasia in a Patient with Germline MAX MutationRomanet, Pauline; Guerin, Carole; Pedini, Pascal; Essamet, Wassim; Castinetti, Frederic; Sebag, Frederic; Roche, Philippe; Cascon, Alberto; Tischler, Arthur S.; Pacak, Karel; Barlier, Anne; Taieb, David 分享 收藏 Protein-Protein Interaction Inhibition (2P21)-Oriented Chemical Library Accelerates Hit DiscoveryMilhas, Sabine; Raux, Brigitt; Betzi, Stephane; Derviaux, Carine; Roche, Philippe; Restouin, Audrey; Basse, Marie-Jeanne; Rebuffet, Etienne; Lugari, Adrien; Badol, Marion; Kashyap, Rudra; Lissitzky, Jean-Claude; Eydoux, Cecilia; Hamon, Veronique; Gourde, Marie -Edith; Combes, Sebastien; Zimmermann, Pascale; Aurrand-Lions, Michel; Roux, Thomas; Rogers, Catherine; Muller, Susanne; Knapp, Stefan; Trinquet, Eric; Collette, Yves; Guillemot, Jean-Claude; Morelli, Xavier 分享 收藏 
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