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J

Jeffrey S. Derrick

merck & company

H指数:20

被引数:1,918

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Development of a Claisen Condensation in Flow toward the Synthesis of MK-7845

通过流动体系下的克莱森缩合反应合成MK-7845

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2026-03-010

PRE

Asymmetric Synthesis of MK-7845, an Investigational Treatment for COVID-19

MK-7845的不对称合成，新型冠状病毒肺炎的研究性治疗

ORGANIC LETTERS

IF5

2025-10-010

PRE

Larson, Reed T.; Turnbull, Ben W. H.; Moon, Patrick J.; Lehnherr, Dan; Hughes, Jonathan M. E.; Popov, Stasik; Brito, Gilmar A.; Andreani, Teresa; Kim, Suhong; Herbort, James; Sifri, Renee J.; Badir, Shorouk O.; Onyeagusi, Chibueze I.; Deprez, Nicholas R.; Otte, Douglas; Gauthier, Donald R.; Kuhl, Nadine; Ji, Yining; Neel, Andrew J.; Cohen, Ryan D.; Derrick, Jeffrey S.; Bottecchia, Cecilia; Hartmanshenn, Clara; Vargas, David A.; Dal Poggetto, Guilherme; Confer, Alex M.; Zheng, Michelle; Qin, Yangzhong; Vikram, Ajit; Newman, Justin A.; Sakhaei, Zeinab; Drout, Riki J.; Chen, Lu; Wu, Zheng; Castro, Steve; Betancourt, Stella K.; Longia, Gurpreet; Kassim, Brittany; Xu, Yingju; Dunn, Jamie M. McCabe; Marzijarani, Nastaran Salehi

A Combined DFT, Energy Decomposition, and Data Analysis Approach to Investigate the Relationship Between Noncovalent Interactions and Selectivity in a Flexible DABCOnium/Chiral Anion Catalyst System

IF13.1

2022-09-2711

OA

Exchange Coupling Determines Metal-Dependent Efficiency for Iron- and Cobalt-Catalyzed Photochemical CO2 Reduction

IF13.1

2022-07-0126

OA

Templating Bicarbonate in the Second Coordination Sphere Enhances Electrochemical CO2 Reduction Catalyzed by Iron Porphyrins

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-06-2463

OA

Deciphering Distinct Overpotential-Dependent Pathways for Electrochemical CO2 Reduction Catalyzed by an Iron-Terpyridine Complex

INORGANIC CHEMISTRY

IF4.7

2022-04-2213

OA

Controlled Single-Electron Transfer via Metal-Ligand Cooperativity Drives Divergent Nickel-Electrocatalyzed Radical Pathways

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-04-2931

OAAI

Consistent inclusion of continuum solvation in energy decomposition analysis: theory and application to molecular CO2 reduction catalysts

CHEMICAL SCIENCE

IF7.4

2021-01-0149

OAAI

Metal-Ligand Cooperativity via Exchange Coupling Promotes Iron-Catalyzed Electrochemical CO2 Reduction at Low Overpotentials

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-11-1891

OAAI

Regio- and Enantioselective Bromocyclization of Difluoroalkenes as a Strategy to Access Tetrasubstituted Difluoromethylene-Containing Stereocenters

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-04-3063

OA

Advanced Electron Paramagnetic Resonance Studies of a Ternary Complex of Copper, Amyloid-β, and a Chemical Regulator

INORGANIC CHEMISTRY

IF4.7

2018-09-215

PREAI

Regulatory Activities of Dopamine and Its Derivatives toward Metal-Free and Metal-Induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer's Disease

ACS CHEMICAL NEUROSCIENCE

IF3.9

2018-05-2175

PREAI

Positional effects of second-sphere amide pendants on electrochemical CO2 reduction catalyzed by iron porphyrins

CHEMICAL SCIENCE

IF7.4

2018-01-01214

OAAI

Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease

IF3.4

2017-10-0916

OAAI

Supramolecular Porphyrin Cages Assembled at Molecular-Materials Interfaces for Electrocatalytic CO Reduction

ACS CENTRAL SCIENCE

IF10.4

2017-09-1371

OAAI

Mechanistic Insights into Tunable Metal-Mediated Hydrolysis of Amyloid-β Peptides

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2017-01-1863

PREAI

Stereochemistry of metal tetramethylcyclam complexes directed by an unexpected anion effect

DALTON TRANSACTIONS

IF3.3

2017-01-0112

PREAI

Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease

NATURE COMMUNICATIONS

IF15.7

2016-10-1379

OAAI

Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-β, and Oxidative Stress in Alzheimer's Disease

INORGANIC CHEMISTRY

IF4.7

2016-04-2720

PREAI

A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2015-11-1763

OA