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P

Paul M. O’Neill

university of liverpool

61H指数
303论文数
1.5W被引数
收录论文 144
发表时间
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Identification of DC-174 as a Novel Hydroxamic Precandidate for the Development of an Oral Snakebite Treatment将DC-174鉴定为一种新型羟肟酸类先导化合物，用于开发口服蛇咬伤治疗方法
errJournal of Medicinal Chemistry
IF6.8
err2026-04-09
err0
errOAAI
errDaniel J. W. Chong; Laura-Oana Albulescu; Adam Westhorpe; Rachel H. Clare; Amy E. Marriott; Christopher M. Woodley; Ramachandran Gunasekar; Nada Mosallam; Edouard Crittenden; Emma Stars; Charlotte Dawson; Jeroen Kool; Mark C. Wilkinson; Suet C. Leung; Neil G. Berry; Nicholas R. Casewell; Paul M. O’Neill
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err收藏
Second-Generation Anti-Tubercular Squaramides Targeting Complex V of the Respiratory Chain of Mycobacterium tuberculosis Displaying Enhanced Metabolic Stability第二代抗结核环脲类化合物靶向结核分枝杆菌呼吸链复合物V并显示增强的代谢稳定性
errJournal of Medicinal Chemistry
IF6.8
err2026-04-01
err0
errOAAI
errMosallam, Nada; O'Neill, Paul M.; Lisauskaite, Monika; Woodley, Christopher M.; Ardrey, Alison; Jeffreys, Laura N.; Memelis, Ilinca; Almeida, Deepak; Lee, Jin; Converse, Paul J.; Cantillon, Daire; Nuermberger, Eric L.; Bald, Dirk; Biagini, Giancarlo A.; Hong, W. David; Berry, Neil G.; Nixon, Gemma L.
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Autophagy is essential for anti-Wolbachia drug efficacy in Brugia malayi and insect cells自噬对于抗沃尔巴克氏体药物在马来丝虫和昆虫细胞中的疗效至关重要。
errFrontiers in Microbiology
IF4.5
err2026-03-16
err0
errOAAI
errAY Anfal Yousef †; EK Ellen K. G. Masters †; YW Yang Wu; WD W. David Hong; PM Paul M. O’Neill; JD Joseph D. Turner; SA Steve A. Ward; MJ Mark J. Taylor
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Potent Preorganized Pyrazolidine Cyclophilin D Inhibitors Prevent Mitochondrial and Organ Injury in a Mouse Pancreatitis Disease Model强效预组织化的吡唑烷环孢菌素D抑制剂可预防小鼠胰腺炎疾病模型中的线粒体和器官损伤
errJournal of Medicinal Chemistry
IF6.8
err2025-11-10
err0
errOAAI
errMuhammad Awais; Christopher M. Woodley; Liqun Guo; Michael Rogers; Neil Kershaw; Thomas Zacharchenko; Emma Shore; Arjun Kattakayam; Rajarshi Mukherjee; David N. Criddle; Suet C. Leung; Heather Lee; Joshua Burgess-McCann; Konstantin Luzyanin; Neil G. Berry; Svetlana Antonyuk; Lu-Yun Lian; Robert Sutton; Paul M. O’Neill
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Novel antimalarial 3-substituted quinolones isosteres with improved pharmacokinetic properties
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
PREAI
errGe, Siyuan; Jian, Rongchao; Xuan, Qiwei; Zhu, Yingxiang; Ren, Xiaofei; Li, Wenjiao; Chen, Xiaole; Huang, Rui-Kang; Lee, Chi-Sing; Leung, Suet C.; Basilico, Nicoletta; Parapini, Silvia; Taramelli, Donatella; Pinthong, Nattapon; Antonyuk, Svetlana, V; O'Neill, Paul M.; Sheng, Zhaojun; Hong, W. David
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Inhibition of PRC2 enables self-renewal of blastoid-competent naive pluripotent stem cells from chimpanzeePRC2的抑制使具有类囊胚能力的原始态多能干细胞在黑猩猩中实现自我更新
errCELL STEM CELL
IF20.4
err2025-02-01
err0
errOAAI
errHuang, Tao; Radley, Arthur; Yanagida, Ayaka; Ren, Zhili; Carlisle, Francesca; Tahajjodi, Somayyeh; Kim, Dongwan; O'Neill, Paul; Clarke, James; Lancaster, Madeline A.; Heckhausen, Zoe; Zhuo, Jingran; de Sousa, Joao Pedro Agostinho; Hajkova, Petra; von Meyenn, Ferdinand; Imai, Hiroo; Nakauchi, Hiromitsu; Guo, Ge; Smith, Austin; Masaki, Hideki
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Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement
errSCIENTIFIC REPORTS
IF3.9
err2024-05-27
err1
errOAAI
errWatanabe, Seiji; Amporndanai, Kangsa; Awais, Raheela; Latham, Caroline; Awais, Muhammad; O'Neill, Paul M.; Yamanaka, Koji; Hasnain, S. Samar
err分享
err收藏
Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2024-02-01
err2
errOAAI
errHegde, Shrilakshmi; Marriott, Amy E.; Pionnier, Nicolas; Steven, Andrew; Bulman, Christina; Gunderson, Emma; Vogel, Ian; Koschel, Marianne; Ehrens, Alexandra; Lustigman, Sara; Voronin, Denis; Tricoche, Nancy; Hoerauf, Achim; Huebner, Marc P.; Sakanari, Judy; Aljayyoussi, Ghaith; Gusovsky, Fabian; Dagley, Jessica; Hong, David W.; O'Neill, Paul; Ward, Steven A.; Taylor, Mark J.; Turner, Joseph D.
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err收藏
Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum
errRSC CHEMICAL BIOLOGY
IF3.1
err2024-01-01
err7
errOAAI
errLisauskaite, Monika; Nixon, Gemma L.; Woodley, Christopher M.; Berry, Neil G.; Coninckx, Andy; Qie, L. Charlie; Leung, Suet C.; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Ward, Stephen A.; Vadas, Oscar; Soldati-Favre, Dominique; Hong, W. David; O'Neill, Paul M.
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err收藏
Dirofilariasis mouse models for heartworm preclinical research
errFRONTIERS IN MICROBIOLOGY
IF4.5
err2023-06-22
err5
errOAAI
errMarriott, A. E.; Dagley, J. L.; Hegde, S.; Steven, A.; Fricks, C.; DiCosty, U.; Mansour, A.; Campbell, E. J.; Wilson, C. M.; Gusovsky, F.; Ward, S. A.; Hong, W. D.; O'Neill, P.; Moorhead, A.; McCall, S.; McCall, J. W.; Taylor, M. J.; Turner, J. D.
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err收藏
Thiazolide Prodrug Esters and Derived Peptides: Synthesis and Activity噻唑化物前体酯和衍生肽: 合成和活性
errACS BIO & MED CHEM AU
IF4.3
err2023-04-11
err0
errOAAI
errStachulski, Andrew V.; Rossignol, Jean-Francois; Pate, Sophie; Taujanskas, Joshua; Iggo, Jonathan A.; Aerts, Rudi; Pascal, Etienne; Piacentini, Sara; La Frazia, Simone; Santoro, M. Gabriella; van Vooren, Lieven; Sintubin, Liesje; Cooper, Mark; Swift, Karl; O'Neill, Paul M.
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Diastereoselective synthesis of a novel phosphinic peptide as ACE inhibitor: Fragment-based design approach作为ACE抑制剂的新型次膦酸肽的非对映选择性合成: 基于片段的设计方法
errARABIAN JOURNAL OF CHEMISTRY
IF5.2
err2023-02-01
err1
errOAAI
errAbdou, Moaz M.; Dong, Dewen; O'Neill, Paul M.; Amigues, Eric; Matziari, Magdalini
err分享
err收藏
Genome-wide characterization of mitochondrial DNA methylation in human brain人脑线粒体DNA甲基化的全基因组表征
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2023-01-16
err12
errOAAI
errDevall, Matthew; Soanes, Darren M.; Smith, Adam R.; Dempster, Emma L.; Smith, Rebecca G.; Burrage, Joe; Iatrou, Artemis; Hannon, Eilis; Troakes, Claire; Moore, Karen; O'Neill, Paul; Al-Sarraj, Safa; Schalkwyk, Leonard; Mill, Jonathan; Weedon, Michael; Lunnon, Katie
err分享
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Transformation of the Manufacturing Process from Discovery to Kilogram Scale for AWZ1066S: A Highly Specific Anti-Wolbachia Drug Candidate for a Short-Course Treatment of Filariasis
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2023-01-10
err0
errOAAI
errHong, W. David; O'Neill, Paul M.; Taylor, Mark J.; Turner, Joseph D.; Ward, Stephen A.; Gusovsky, Fabian; Benayoud, Farid; Shibuguchi, Nao; Girish, Dixit; Fang, Francis Gerard; Talabhakthla, Ravi Kumar; Vaddi, Anand; Challa, Chiranjeevi; Reddy, Karri Satya Ammi; Kalla, Vijay; Rao, Sugandham Srinivasa; Nagireddi, Durga Mahesh Kumar; Patel, Jayesh; Khile, Anil Shahaji
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Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis
errACS INFECTIOUS DISEASES
IF3.8
err2023-01-06
err16
errOAAI
errJeffreys, Laura N.; Ardrey, Alison; Hafiz, Taghreed A.; Dyer, Lauri-Anne; Warman, Ashley J.; Mosallam, Nada; Nixon, Gemma L.; Fisher, Nicholas E.; Hong, W. David; Leung, Suet C.; Aljayyoussi, Ghaith; Bibby, Jaclyn; V. Almeida, Deepak; Converse, Paul J.; Fotouhi, Nader; Berry, Neil G.; Nuermberger, Eric L.; Upton, Anna M.; O'Neill, Paul M.; Ward, Stephen A.; Biagini, Giancarlo A.
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Recent Advances of DprE1 Inhibitors against Mycobacterium tuberculosis: Computational Analysis of Physicochemical and ADMET Properties
errACS OMEGA
IF4.3
err2022-11-03
err25
errOAAI
errAmado, Patricia S. M.; Woodley, Christopher; Cristiano, Maria L. S.; O'Neill, Paul M.
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Structure-based bioisosteric design, synthesis and biological evaluation of novel pyrimidines as antiplasmodial antifolate agents
errJOURNAL OF SAUDI CHEMICAL SOCIETY
IF5.8
err2022-11-01
err8
errOAAI
errAbdou, Moaz M.; O'Neill, Paul M.; Amigues, Eric; Matziari, Magdalini
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err收藏
Design, Synthesis, and Study of a Novel RXPA380-Proline Hybrid (RXPA380-P) as an Antihypertensive Agent
errACS OMEGA
IF4.3
err2022-09-23
err4
errOAAI
errAbdou, Moaz M.; Dong, Dewen; O'Neill, Paul M.; Amigues, Eric; Matziari, Magdalini
err分享
err收藏
Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials
errBIOLOGY-BASEL
IF3.5
err2022-07-25
err12
errOAAI
errAmporndanai, Kangsa; Pinthong, Nattapon; O'Neill, Paul M.; Hong, W. David; Amewu, Richard K.; Pidathala, Chandrakala; Berry, Neil G.; Leung, Suet C.; Ward, Stephen A.; Biagini, Giancarlo A.; Hasnain, S. Samar; Antonyuk, Svetlana, V
err分享
err收藏
Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
errACS OMEGA
IF4.3
err2022-06-16
err5
errOAAI
errAbdou, Moaz M.; O'Neill, Paul M.; Amigues, Eric; Matziari, Magdalini
err分享
err收藏

研究方向

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合作学者
合作期刊
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Benjamin F. Cravatt
H 指数: 148 · 论文数: 867
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H 指数: 111 · 论文数: 1.4K
S
Sangeeta N. Bhatia
H 指数: 111 · 论文数: 524
J
JeffriesAaron (Jonathan Mill)
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