Derek Dang

university of michigan system

H指数:11

被引数:442

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ZFTA-RELA ependymomas make itaconate to epigenetically drive fusion expression

Nature

IF48.5

2026-02-012

PRE

Natarajan, Siva Kumar; Lum, Joanna; Skeans, James Haggerty; Nenwani, Minal; Eyunni, Sanjana; Mota, Mateus; Bayliss, Jill M.; Deogharkar, Akash; Hamanishi, Erin Taya; Pun, Matthew; Sweha, Stefan R.; Hoffman, Simon; Young, Eleanor; Zhang, Qiuyang; Mehta, Rijul; Animasahun, Olamide; Narayanan, Pranav; Sunil, Sushanth; Parolia, Abhijit; Sajjakulnukit, Peter; Panwalkar, Pooja; Doherty, Robert; Clausen, Madison; Dang, Derek; Hawes, Debra; Yang, Fusheng; Santi, Mariarita; Judkins, Alexander R.; Wilson, Yelena; Vigil, Thomas; Franson, Andrea; Mortensen, Richard M.; Ozawa, Tatsuya; Griesinger, Andrea; Holland, Eric C.; Foreman, Nicholas K.; Michealraj, Kulandaimanuvel Antony; Agnihotri, Sameer; Taylor, Michael; Gilbertson, Richard J.; Koschmann, Carl; Chinnaiyan, Arul M.; Lyssiotis, Costas A.; Nagrath, Deepak; Venneti, Sriram

Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis

异柠檬酸脱氢酶1为组3型髓母细胞瘤的铜死亡做准备

Cancer Cell

IF44.5

2025-05-150

PRE

Derek Dang; Akash Deogharkar; John McKolay; Kyle S. Smith; Pooja Panwalkar; Simon Hoffman; Wentao Tian; Sunjong Ji; Ana P. Azambuja; Siva Kumar Natarajan; Joanna Lum; Jill Bayliss; Katie Manzeck; Stefan R. Sweha; Erin Hamanishi; Matthew Pun; Diya Patel; Sagar Rau; Olamide Animasahun; Abhinav Achreja; Martin P. Ogrodzinski; Jutta Diessl; Jennifer Cotter; Debra Hawes; Fusheng Yang; Robert Doherty; Andrea T. Franson; Allison R. Hanaford; Charles G. Eberhart; Eric H. Raabe; Brent A. Orr; Robert J. Wechsler-Reya; Brandon Chen; Costas A. Lyssiotis; Yatrik M. Shah; Sophia Y. Lunt; Ruma Banerjee; Alexander R. Judkins; John R. Prensner; Carl Koschmann; Sebastian M. Waszak; Deepak Nagrath; Marcos Simoes-Costa; Paul A. Northcott; Sriram Venneti

Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

NATURE COMMUNICATIONS

IF15.7

2024-10-170

OAAI

ISOCITRATE DEHYDROGENASE 1 INHIBITION PRIMES GROUP-3 MEDULLOBLASTOMAS FOR CUPROPTOSIS

NEURO-ONCOLOGY

IF13.4

2024-06-180

OAAI

Dang, Derek; McKolay, John; Smith, Kyle; Panwalkar, Pooja; Sweha, Stefan; Natarajan, Siva Kumar; Pun, Matthew J.; Ji, Sunjong; Patel, Diya; Animasahun, Olamide; Achreja, Abhinav; Ogrodzinski, Martin P.; Cotter, Jennifer; Hawes, Debra; Yang, Fusheng; Doherty, Robert; Franson, Andrea T.; Hanaford, Allison R.; Eberhart, Charles G.; Raabe, Eric H.; Chen, Brandon; Lyssiotis, Costas A.; Shah, Yatrik; Lunt, Sophia Y.; Judkins, Alexander R.; Prensner, John; Koschmann, Carl J.; Waszak, Sebastian; Nagrath, Deepak; Northcott, Paul; Venneti, Sriram

Clinical, genomic, and epigenomic analyses of H3K27M-mutant diffuse midline glioma long-term survivors reveal a distinct group of tumors with MAPK pathway alterations

ACTA NEUROPATHOLOGICA

IF9.3

2023-10-1814

OAAI

Roberts, Holly J.; Ji, Sunjong; Picca, Alberto; Sanson, Marc; Garcia, Mekka; Snuderl, Matija; Schueller, Ulrich; Picart, Thiebaud; Ducray, Francois; Green, Adam L.; Nakano, Yoshiko; Sturm, Dominik; Abdullaev, Zied; Aldape, Kenneth; Dang, Derek; Kumar-Sinha, Chandan; Wu, Yi-Mi; Robinson, Dan; Vo, Josh N.; Chinnaiyan, Arul M.; Cartaxo, Rodrigo; Upadhyaya, Santhosh A.; Mody, Rajen; Chiang, Jason; Baker, Suzanne; Solomon, David; Venneti, Sriram; Pratt, Drew; Waszak, Sebastian M.; Koschmann, Carl

β-Catenin-Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer

CANCER RESEARCH

IF16.6

2023-05-023

Mohan, Dipika R.; Borges, Kleiton S.; Finco, Isabella; LaPensee, Christopher R.; Rege, Juilee; Solon, April L.; Little III, Donald W.; Else, Tobias; Almeida, Madson Q.; Dang, Derek; Haggerty-Skeans, James; Apfelbaum, April A.; Vinco, Michelle; Wakamatsu, Alda; Mariani, Beatriz M. P.; Amorim, Larissa Costa; Latronico, Ana Claudia; Mendonca, Berenice B.; Zerbini, Maria Claudia N.; Lawlor, Elizabeth R.; Ohi, Ryoma; Auchus, Richard J.; Rainey, William E.; Marie, Suely K. N.; Giordano, Thomas J.; Venneti, Sriram; Fragoso, Maria Candida Barisson Villares; Breault, David T.; Lerario, Antonio Marcondes; Hammer, Gary D.

Investigating metabolic dependencies of group 3 medulloblastoma

CANCER RESEARCH

IF16.6

2023-04-040

PRE

Epigenetic dedifferentiation as a therapeutic strategy in adrenal cancer

CANCER RESEARCH

IF16.6

2023-04-040

PRE

ZFTA-RELA fusion aberrantly drives glutamine metabolism in lethal pediatric ependymomas

CANCER RESEARCH

IF16.6

2023-04-040

PRE

Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas

针对致死性儿童PFA室管瘤的整合表观遗传和代谢途径

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-10-0630

Panwalkar, Pooja; Tamrazi, Benita; Dang, Derek; Chung, Chan; Sweha, Stefan; Natarajan, Siva Kumar; Pun, Matthew; Bayliss, Jill; Ogrodzinski, Martin P.; Pratt, Drew; Mullan, Brendan; Hawes, Debra; Yang, Fusheng; Lu, Chao; Sabari, Benjamin R.; Achreja, Abhinav; Heon, Jin; Animasahun, Olamide; Cieslik, Marcin; Dunham, Christopher; Yip, Stephen; Hukin, Juliette; Phillips, Joanna J.; Bornhorst, Miriam; Griesinger, Andrea M.; Donson, Andrew M.; Foreman, Nicholas K.; Garton, Hugh J. L.; Heth, Jason; Muraszko, Karin; Nazarian, Javad; Koschmann, Carl; Jiang, Li; Filbin, Mariella G.; Nagrath, Deepak; Kool, Marcel; Korshunov, Andrey; Pfister, Stefan M.; Gilbertson, Richard J.; Allis, C. David; Chinnaiyan, Arul M.; Lunt, Sophia Y.; Bluml, Stefan; Judkins, Alexander R.; Venneti, Sriram

Evidence of disrupted rhombic lip development in the pathogenesis of Dandy-Walker malformation

ACTA NEUROPATHOLOGICA

IF9.3

2021-08-0420

OAAI

SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors

NEURO-ONCOLOGY

IF13.4

2020-02-1224

OAAI

HETEROGENEITY OF BMF AND PBAF SWI/SNT COMPLEX SUBUNITS IN MALIGNANT RHABDOID TUMORS RELATES WITH POLYPHENOTYPIC DIFFERENTIATION AND THE. IMMUNE MICROENVIRONMENT

NEURO-ONCOLOGY