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CONVENTIONAL TYPE 1 DENDRITIC CELLS ENHANCE NEUROPROTECTION IN PEDIATRIC BRAIN TUMOR RADIOTHERAPY 常规类型1树突状细胞增强儿科脑肿瘤放疗中的神经保护作用 Marco-Sanz, J.; Lacalle, A.; Morales, S.; Nuin, S.; Palacios-Alonso, D.; Beasain, I; Ausejo-Mauleon, I; de la Nava, D.; Hernandez-Osuna, R.; Patino-Garcia, A.; Gallego Perez-Larraya, J.; Huang, A.; Garcia-Osta, A.; Alonso, M.; Labiano, S. 分享 收藏
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Resilience to structural and molecular changes in excitatory synapses in the hippocampus contributes to cognitive function recovery in Tg2576 mice Aguado, Carolina; Badesso, Sara; Martinez-Hernandez, Jose; Martin-Belmonte, Alejandro; Alfaro-Ruiz, Rocio; Fernandez, Miriam; Moreno-Martinez, Ana Esther; Cuadrado-Tejedor, Mar; Garcia-Osta, Ana; Lujan, Rafael 分享 收藏
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Improvement of cognitive function in wild-type and Alzheimer's disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells Casares, Noelia; Alfaro, Maria; Cuadrado-Tejedor, Mar; Lasarte-Cia, Aritz; Navarro, Flor; Vivas, Isabel; Espelosin, Maria; Cartas-Cejudo, Paz; Fernandez-Irigoyen, Joaquin; Santamaria, Enrique; Garcia-Osta, Ana; Lasarte, Juan Jose 分享 收藏
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PLA2G4E, a candidate gene for resilience in Alzheimer's disease and a new target for dementia treatment Perez-Gonzalez, Marta; Mendioroz, Maite; Badesso, Sara; Sucunza, Diego; Roldan, Miren; Espelosin, Maria; Ursua, Susana; Lujan, Rafael; Cuadrado-Tejedor, Mar; Garcia-Osta, Ana 分享 收藏
Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles Rabal, Obdulia; Sanchez-Arias, Juan A.; Cuadrado-Tejedor, Mar; de Miguel, Irene; Perez-Gonzalez, Marta; Garcia-Barroso, Carolina; Ugarte, Ana; Estella-Hermoso de Mendoza, Ander; Saez, Elena; Espelosin, Maria; Ursua, Susana; Tan, Haizhong; Wu, Wei; Xu, Musheng; Pineda-Lucena, Antonio; Garcia-Osta, Ana; Oyarzabal, Julen 分享 收藏
Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer's Disease Cuadrado-Tejedor, Mar; Perez-Gonzalez, Marta; Garcia-Munoz, Cristina; Muruzabal, Damian; Garcia-Barroso, Carolina; Rabal, Obdulia; Segura, Victor; Sanchez-Arias, Juan A.; Oyarzabal, Julen; Garcia-Osta, Ana 分享 收藏
Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy Martier, Raygene; Liefhebber, Jolanda M.; Garcia-Osta, Ana; Miniarikova, Jana; Cuadrado-Tejedor, Mar; Espelosin, Maria; Ursua, Susana; Petry, Harald; van Deventer, Sander J.; Evers, Melvin M.; Konstantinova, Pavlina 分享 收藏
Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors 用于治疗阿尔茨海默病的体内化学探针的发现: 双重磷酸二酯酶5 (PDE5) 和I类组蛋白脱乙酰酶选择性抑制剂 Rabal, Obdulia; Sanchez-Arias, Juan A.; Cuadrado-Tejedor, Mar; de Miguel, Irene; Perez-Gonzalez, Marta; Garcia-Barroso, Carolina; Ugarte, Ana; Estella-Hermoso de Mendoza, Ander; Saez, Elena; Espelosin, Maria; Ursua, Susana; Tan Haizhong; Wei, Wu; Xu Musheng; Garcia-Osta, Ana; Oyarzabal, Julen 分享 收藏
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Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease Rabal, Obdulia; Sanchez-Arias, Juan A.; Cuadrado-Tejedor, Mar; de Miguel, Irene; Perez-Gonzalez, Marta; Garcia-Barroso, Carolina; Ugarte, Ana; Estella-Hermoso de Mendoza, Ander; Saez, Elena; Espelosin, Maria; Ursua, Susana; Tan Haizhong; Wei, Wu; Xu Musheng; Garcia-Osta, Ana; Oyarzabal, Julen 分享 收藏
Immunomodulatory Properties of Carvone Inhalation and Its Effects on Contextual Fear Memory in Mice Lasarte-Cia, Aritz; Lozano, Teresa; Perez-Gonzalez, Marta; Gorraiz, Marta; Iribarren, Kristina; Hervas-Stubbs, Sandra; Sarobe, Pablo; Rabal, Obdulia; Cuadrado-Tejedor, Mar; Garcia-Osta, Ana; Casares, Noelia; Jose Lasarte, Juan 分享 收藏
The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma Aldave, Guillermo; Gonzalez-Huarriz, Marisol; Rubio, Angel; Pablo Romero, Juan; Ravi, Datta; Minana, Belen; Cuadrado-Tejedor, Mar; Garcia-Osta, Ana; Verhaak, Roeland; Xipell, Enric; Martinez-Velez, Naiara; Acanda de la Rocha, Arlet; Puigdelloses, Montserrat; Garcia-Moure, Marc; Marigil, Miguel; Gallego Perez-Larraya, Jaime; Marin-Bejar, Oskar; Huarte, Maite; Carro, Maria Stella; Ferrarese, Roberto; Belda-Iniesta, Cristobal; Ayuso, Angel; Prat-Acin, Ricardo; Pastor, Fernando; Diez-Valle, Ricardo; Tejada, Sonia; Alonso, Marta M. 分享 收藏
Impact of Scaffold Exploration on Novel Dual-Acting Histone Deacetylases and Phosphodiesterase 5 Inhibitors for the Treatment of Alzheimer's Disease Sanchez-Arias, Juan A.; Rabal, Obdulia; Cuadrado-Tejedor, Mar; de Miguel, Irene; Perez-Gonzalez, Marta; Ugartet, Ana; Saez, Elena; Espelosin, Maria; Ursua, Susana; Tan Haizhong; Wu Wei; Xu Musheng; Garcia-Osta, Ana; Oyarzabal, Julen 分享 收藏
Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease Rabal, Obdulia; Sanchez-Arias, Juan A.; Cuadrado-Tejedor, Mar; de Miguel, Irene; Perez-Gonzalez, Marta; Garcia-Barroso, Carolina; Ugarte, Ana; Estella-Hermoso de Mendoza, Ander; Saez, Elena; Espelosin, Maria; Ursua, Susana; Tan Haizhong; Wei, Wu; Xu Musheng; Garcia-Osta, Ana; Oyarzabal, Julen 分享 收藏